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 Predicate ID,Triple,Sentence ID,Sentence,Is Correct,Question,Answer
-26452786,Fenbendazole causes helminthiasis,1001,Evaluation of granulated fenbendazole (22.2%) against induced and naturally occurring helminth infections in cats.,False,Is the triple 'Fenbendazole causes helminthiasis' supported by the sentence: 'Evaluation of granulated fenbendazole (22.2%) against induced and naturally occurring helminth infections in cats.'?,"No, because the statement suggests that Fenbendazole is used to treat helminthiasis, not cause it."
-24413653,Fenbendazole treats helminthiasis,1002,"This study investigated worm control practices by free-range egg farmers and the efficacy of the commercial anthelmintics levamisole (LEV), piperazine (PIP), flubendazole (FLBZ) and fenbendazole (FBZ) against gastrointestinal nematodes on two free-range layer farms in Australia.",True,"Is the triple 'Fenbendazole treats helminthiasis' supported by the sentence: 'This study investigated worm control practices by free-range egg farmers and the efficacy of the commercial anthelmintics levamisole (LEV), piperazine (PIP), flubendazole (FLBZ) and fenbendazole (FBZ) against gastrointestinal nematodes on two free-range layer farms in Australia.'?","Yes, the statement ""Fenbendazole treats helminthiasis"" is indirectly supported by the provided sentence as it mentions fenbendazole (FBZ) as one of the commercial anthelmintics being tested for its efficacy against gastrointestinal nematodes, which can be classified as a type of helminthiasis."
-22762728,Fenbendazole prevents helminthiasis,1003,Fenbendazole resistance in O. ostertagi was confirmed with a total treatment failure in reducing worm burden: efficacy of 0%.,False,Is the triple 'Fenbendazole prevents helminthiasis' supported by the sentence: 'Fenbendazole resistance in O. ostertagi was confirmed with a total treatment failure in reducing worm burden: efficacy of 0%.'?,"No, it is not directly supported because a statement about Fenbendazole's effectiveness against helminthiasis would require direct evidence of its impact on that specific condition, not just its effect on worm burden in a different context."
-9783282,Thiabendazole treats helminthiasis,1004,[The treatment of helminthiasis with thiabendazole].,True,Is the triple 'Thiabendazole treats helminthiasis' supported by the sentence: '[The treatment of helminthiasis with thiabendazole].'?,"Yes, the statement ""Thiabendazole treats helminthiasis"" is indeed directly supported by the given sentence, as it clearly states that helminthiasis is being treated with thiabendazole."
-21848143,Albendazole causes helminthiasis,1005,Symptoms of perianal itching and visualization of visible motile worms persisted for 6 months despite being treated with multiple courses of albendazole causing a lot of frustration and distress to the caregivers.,False,Is the triple 'Albendazole causes helminthiasis' supported by the sentence: 'Symptoms of perianal itching and visualization of visible motile worms persisted for 6 months despite being treated with multiple courses of albendazole causing a lot of frustration and distress to the caregivers.'?,"No, this statement does not support the claim that albendazole causes helminthiasis (a condition characterized by parasitic worm infestations). Instead, it suggests that despite treatment with albendazole, symptoms of a worm infestation persisted for 6 months, causing distress to caregivers."
-25735916,Albendazole affects trichuriasis,1006,"Ovicidal effects of albendazole in human ascariasis, ancylostomiasis and trichuriasis.",True,"Is the triple 'Albendazole affects trichuriasis' supported by the sentence: 'Ovicidal effects of albendazole in human ascariasis, ancylostomiasis and trichuriasis.'?","Yes, the statement Albendazole affects trichuriasis is indirectly supported by the given sentence as it mentions that Albendazole has ovicidal effects on Trichuriasis, which means it can affect it, although it does not explicitly state that it treats it."
-24685635,Albendazole affects filarial elephantiasis,1007,"A combination of drugs Ivermectin, Diethylcarbamazine citrate and Albendazole is recommended by WHO to accelerate the Global Programme to Eliminate Lymphatic Filariasis (GPELF).",False,"Is the triple 'Albendazole affects filarial elephantiasis' supported by the sentence: 'A combination of drugs Ivermectin, Diethylcarbamazine citrate and Albendazole is recommended by WHO to accelerate the Global Programme to Eliminate Lymphatic Filariasis (GPELF).'?","No. The given statement does not provide direct support for the claim that Albendazole affects filarial elephantiasis. It only mentions that a combination of Ivermectin, Diethylcarbamazine citrate, and Albendazole is recommended by WHO for a program to eliminate lymphatic filariasis. It does not specify how Albendazole impacts filarial elephantiasis specifically."
-18452252,Albendazole affects toxocariasis,1008,Effect of albendazole in experimental toxocariasis of mice.,False,Is the triple 'Albendazole affects toxocariasis' supported by the sentence: 'Effect of albendazole in experimental toxocariasis of mice.'?,"No, it is not directly supported. The given statement talks about an experiment on mice, whereas your question pertains to humans (indicated by 'affects'). Furthermore, it does not explicitly mention a decrease, improvement, or any positive effect on toxocariasis, it merely states that there is an effect, which could be positive, negative, or neutral."
-16658505,Albendazole affects malaria,1009,"Given the low helminth prevalence in our children, the effect of albendazole on malaria is likely to be direct.",True,"Is the triple 'Albendazole affects malaria' supported by the sentence: 'Given the low helminth prevalence in our children, the effect of albendazole on malaria is likely to be direct.'?","Yes. The statement suggests that because there is a low presence of helminths (worms) in these particular children, any impact that albendazole has on malaria is likely to be direct, not indirect through its effects on worms. This implies that albendazole could potentially have a direct therapeutic role in treating malaria, independent of its anti-helminthic properties. However, this is a hypothesis that would need to be tested through further research."
-13946207,Albendazole affects helminthiasis,1010,"Mass co-administration of ivermectin and albendazole by the LFEP had a significant effect on STH, which was further amplified by treatment with praziquantel and albendazole 4 months later.",False,"Is the triple 'Albendazole affects helminthiasis' supported by the sentence: 'Mass co-administration of ivermectin and albendazole by the LFEP had a significant effect on STH, which was further amplified by treatment with praziquantel and albendazole 4 months later.'?","No, the given sentence does not provide direct support for the statement that ""Albendazole affects helminthiasis"". It mentions that mass co-administration of ivermectin and albendazole had a significant effect on Soil Transmitted Helminths (STH), but it does not specifically attribute this effect to albendazole alone."
-11239060,Albendazole affects filariasis,1011,The effect of single dose ivermectin alone or in combination with albendazole on Wuchereria bancrofti infection in primary school children in Tanzania.,False,Is the triple 'Albendazole affects filariasis' supported by the sentence: 'The effect of single dose ivermectin alone or in combination with albendazole on Wuchereria bancrofti infection in primary school children in Tanzania.'?,"No, the statement ""Albendazole affects filariasis"" is not directly supported by the given sentence, as it does not mention the impact of albendazole on filariasis specifically, but rather discusses the effects of a treatment regimen involving both albendazole and ivermectin on Wuchereria bancrofti infection, which is one form of filariasis."
-22678969,Albendazole treats Infection,1012,The control of STH infections is based on preventive chemotherapy using either albendazole or mebendazole.,False,Is the triple 'Albendazole treats Infection' supported by the sentence: 'The control of STH infections is based on preventive chemotherapy using either albendazole or mebendazole.'?,"No, it's not directly supported because the original sentence mentions both albendazole and mebendazole as options for preventive chemotherapy, not specifically for treating infection."
-10750815,Albendazole treats onchocerciasis,1013,"A double-blind clinical trial was conducted in Monagas State, Venezuela to assess the tolerance and efficacy of albendazole in the therapy of Onchocerca volvulus infection.",False,"Is the triple 'Albendazole treats onchocerciasis' supported by the sentence: 'A double-blind clinical trial was conducted in Monagas State, Venezuela to assess the tolerance and efficacy of albendazole in the therapy of Onchocerca volvulus infection.'?","No, it is not directly supported. The given sentence is about a study that assessed the tolerance and efficacy of albendazole for Onchocerca volvulus infection, but it does not explicitly state that albendazole treats onchocerciasis."
-10114050,Albendazole treats toxocariasis,1014,"The treatment of cutaneous larva migrans and Toxocara infection relies on antihelminthic agents such as thiabendazole, albendazole and ivermectin.",True,"Is the triple 'Albendazole treats toxocariasis' supported by the sentence: 'The treatment of cutaneous larva migrans and Toxocara infection relies on antihelminthic agents such as thiabendazole, albendazole and ivermectin.'?","Yes, the statement 'Albendazole treats toxocariasis' is indirectly supported by the provided sentence, as it mentions Albendazole as a treatment for Toxocara infection, which is a form of toxocariasis."
-9588560,Albendazole treats trichuriasis,1015,"Three randomized clinical studies were conducted in 2000 to evaluate the efficacy of nitazoxanide paediatric suspension compared to albendazole in the treatment of ascariasis and trichuriasis and praziquantel in the treatment of hymenolepiasis in children from Cajamarca, Peru.",False,"Is the triple 'Albendazole treats trichuriasis' supported by the sentence: 'Three randomized clinical studies were conducted in 2000 to evaluate the efficacy of nitazoxanide paediatric suspension compared to albendazole in the treatment of ascariasis and trichuriasis and praziquantel in the treatment of hymenolepiasis in children from Cajamarca, Peru.'?","No, it is not directly supported because the sentence mentions nitazoxanide, not albendazole, as being compared to other treatments for different types of parasitic infections."
-9492446,Albendazole treats filariasis,1016,"Today, the only way is the prophylactic control of Onchocerca vovulus infections and treating lymphatic filariosis with ivermectin, diethylcarbamacine, ivermectin/diethylcarbamazine. or ivermectin/albendazole combinations.",False,"Is the triple 'Albendazole treats filariasis' supported by the sentence: 'Today, the only way is the prophylactic control of Onchocerca vovulus infections and treating lymphatic filariosis with ivermectin, diethylcarbamacine, ivermectin/diethylcarbamazine. or ivermectin/albendazole combinations.'?","No. The given statement does not provide direct support for the claim that 'Albendazole treats filariasis'. The statement mentions various treatment options for lymphatic filariosis (which can be caused by different types of worms, including those that cause filariasis), but it does not explicitly associate Albendazole with the treatment of filariasis."
-8712067,Albendazole treats helminthiasis,1017,The study population was assessed for helminthic infection and those found to be positive were randomly assigned to either an albendazole treatment group or a control group who received a placebo.,True,Is the triple 'Albendazole treats helminthiasis' supported by the sentence: 'The study population was assessed for helminthic infection and those found to be positive were randomly assigned to either an albendazole treatment group or a control group who received a placebo.'?,"Yes, the statement ""Albendazole treats helminthiasis"" is indirectly supported by the given sentence. The sentence states that a group of individuals with helminthic infection were treated with albendazole, implying that albendazole is used to treat this condition. However, it's important to note that this is an inference based on the provided sentence, not a direct statement from it."
-7789677,Albendazole treats strongyloidiasis,1018,"To determine the host factors involved in response to treatment, 46 patients with strongyloidiasis were treated with albendazole, followed-up for 1 year, and separated into two groups: cured and non-cured.",False,"Is the triple 'Albendazole treats strongyloidiasis' supported by the sentence: 'To determine the host factors involved in response to treatment, 46 patients with strongyloidiasis were treated with albendazole, followed-up for 1 year, and separated into two groups: cured and non-cured.'?","No, it is not directly supported because this statement does not confirm that Albendazole specifically treats strongyloidiasis, it only states that it was used as a treatment for patients with strongyloidiasis."
-7640018,Albendazole treats filarial elephantiasis,1019,The role of albendazole in programmes to eliminate lymphatic filariasis.,False,Is the triple 'Albendazole treats filarial elephantiasis' supported by the sentence: 'The role of albendazole in programmes to eliminate lymphatic filariasis.'?,"No, it's not directly supported because the given sentence discusses the role of Albendazole in programs to eliminate lymphatic filariasis, not specifically that it treats filarial elephantiasis. However, it implies that Albendazole is used to treat some form of lymphatic filariasis, which could include filarial elephantiasis."
-7620262,Albendazole treats Hookworm Infections,1020,On the basis of our results the single 400 mg dose of albendazole is the treatment of choice for hookworm infections in this region of Mali.,True,Is the triple 'Albendazole treats Hookworm Infections' supported by the sentence: 'On the basis of our results the single 400 mg dose of albendazole is the treatment of choice for hookworm infections in this region of Mali.'?,"Yes, it is indirectly supported because if albendazole is the treatment of choice for hookworm infections in a specific region, then it implies that albendazole can treat hookworm infections, but it does not explicitly state that albendazole treats hookworm infections in all cases, as stated in your first sentence."
-7226097,Albendazole treats cysticercosis,1021,The efficacy of albendazole (15 mg/kg/d for 1 week) was compared with praziquantel (100 mg/kg in three divided doses at 2-hour intervals) for therapy of parenchymal brain cysticercosis.,False,Is the triple 'Albendazole treats cysticercosis' supported by the sentence: 'The efficacy of albendazole (15 mg/kg/d for 1 week) was compared with praziquantel (100 mg/kg in three divided doses at 2-hour intervals) for therapy of parenchymal brain cysticercosis.'?,"No, it is not directly supported. The given sentence compares two treatments for parenchymal brain cysticercosis, one being a regimen of Albendazole and the other Praziquantel, but it does not explicitly state that Albendazole treats cysticercosis."
-24729219,Albendazole disrupts helminthiasis,1022,"Additionally, compared with albendazole, it resulted in a significant reduction in adult worm and total larval counts; moreover, it caused a decrease in the number of larvae deposited in muscles, with a highly significant decrease in the inflammatory cell infiltrate around the larvae and a considerable decrease in the expression of the angiogenic marker vascular endothelial growth factor in muscles.",False,"Is the triple 'Albendazole disrupts helminthiasis' supported by the sentence: 'Additionally, compared with albendazole, it resulted in a significant reduction in adult worm and total larval counts; moreover, it caused a decrease in the number of larvae deposited in muscles, with a highly significant decrease in the inflammatory cell infiltrate around the larvae and a considerable decrease in the expression of the angiogenic marker vascular endothelial growth factor in muscles.'?","No, the statement does not directly support the triple 'Albendazole disrupts helminthiasis'. It suggests that another drug is more effective than Albendazole in reducing worm counts, larvae deposits, inflammatory cell infiltrate, and vascular endothelial growth factor expression in muscles, which implies that Albendazole may not be as effective in treating helminthiasis as this other drug. However, it does not explicitly state that Albendazole 'disrupts' helminthiasis."
-16658503,Albendazole disrupts malaria,1023,"Quarterly albendazole during childhood was associated with reduced incidence of clinical malaria (HR 0.85 (95% CI 0.73-0.98), p = 0.03).",False,"Is the triple 'Albendazole disrupts malaria' supported by the sentence: 'Quarterly albendazole during childhood was associated with reduced incidence of clinical malaria (HR 0.85 (95% CI 0.73-0.98), p = 0.03).'?","No, it is not directly supported because the original statement speaks about quarterly albendazole being associated with a reduction in clinical malaria, not specifically that it 'disrupts' it."
-13637338,Albendazole disrupts Hookworm Infections,1024,CONCLUSIONS: Mebendazole and albendazole showed reduced efficacy against Ascaris lumbricoides and hookworm infections at the recommended doses.,False,Is the triple 'Albendazole disrupts Hookworm Infections' supported by the sentence: 'CONCLUSIONS: Mebendazole and albendazole showed reduced efficacy against Ascaris lumbricoides and hookworm infections at the recommended doses.'?,"No, it is not. The sentence mentions that both albendazole and mebendazole showed reduced efficacy against hookworm infections, but it does not specifically state that albendazole disrupts hookworm infections."
-15248433,Albendazole prevents filariasis,1025,Evaluation of effectiveness of diethylcarbamazine/albendazole combination in reduction of Wuchereria bancrofti infection using multiple infection parameters.,False,Is the triple 'Albendazole prevents filariasis' supported by the sentence: 'Evaluation of effectiveness of diethylcarbamazine/albendazole combination in reduction of Wuchereria bancrofti infection using multiple infection parameters.'?,"No, it is not directly supported. The given sentence evaluates the combination of diethylcarbamazine and albendazole, not albendazole alone, in reducing Wuchereria bancrofti infection."
-13732336,Albendazole prevents helminthiasis,1026,"Our evaluation suggests that although additional studies are needed to determine optimal treatment regimens for intestinal parasites, especially among young children and pregnant women, a five-day course of pre-departure albendazole was effective in reducing helminthic infection in treated refugees.",True,"Is the triple 'Albendazole prevents helminthiasis' supported by the sentence: 'Our evaluation suggests that although additional studies are needed to determine optimal treatment regimens for intestinal parasites, especially among young children and pregnant women, a five-day course of pre-departure albendazole was effective in reducing helminthic infection in treated refugees.'?","Yes, the statement ""Albendazole prevents helminthiasis"" is indirectly supported by your provided sentence, as it mentions a five-day course of pre-departure albendazole being effective in reducing helminthic infection in treated refugees, implying a preventive effect of albendazole on helminthiasis, which is a condition caused by helminths, a type of parasitic worm. However, please note that this is an indirect inference, as your original sentence does not explicitly state that albendazole prevents helminthiasis."
-25678577,Latamoxef treats bacterial infectious disease,1027,"Clinical efficacy and safety of a new oxacephem, moxalactam, in serious bacterial infections.",False,"Is the triple 'Latamoxef treats bacterial infectious disease' supported by the sentence: 'Clinical efficacy and safety of a new oxacephem, moxalactam, in serious bacterial infections.'?","No, it is not directly supported because Latamoxef is not mentioned in this specific sentence, which discusses moxalactam, another antibiotic in the same class (oxacephem)."
-15316470,Ibuprofen subclass of 2-Hydroxyibuprofen,1028,"The purpose of this study was the development and validation of an LC-MS-MS method for simultaneous analysis of ibuprofen (IBP), 2-hydroxyibuprofen (2-OH-IBP) enantiomers, and carboxyibuprofen (COOH-IBP) stereoisomers in fungi culture medium, to investigate the ability of some endophytic fungi to biotransform the chiral drug IBP into its metabolites.",False,"Is the triple 'Ibuprofen subclass of 2-Hydroxyibuprofen' supported by the sentence: 'The purpose of this study was the development and validation of an LC-MS-MS method for simultaneous analysis of ibuprofen (IBP), 2-hydroxyibuprofen (2-OH-IBP) enantiomers, and carboxyibuprofen (COOH-IBP) stereoisomers in fungi culture medium, to investigate the ability of some endophytic fungi to biotransform the chiral drug IBP into its metabolites.'?","No, the statement does not provide direct evidence that ibuprofen subclasses into 2-hydroxyibuprofen. It mentions an investigation into the biotransformation of ibuprofen into its metabolites, including 2-hydroxyibuprofen, but it does not explicitly state that ibuprofen is a subclass of 2-hydroxyibuprofen."
-16265626,Ibuprofen related to Arthralgia,1029,"AIMS: To carry out a randomized clinical trial to compare the effect of palmitoylethanolamide (PEA) versus ibuprofen, a nonsteroidal anti-inflammatory drug (NSAID), for pain relief in temporomandibular joint (TMJ) osteoarthritis or arthralgia.",False,"Is the triple 'Ibuprofen related to Arthralgia' supported by the sentence: 'AIMS: To carry out a randomized clinical trial to compare the effect of palmitoylethanolamide (PEA) versus ibuprofen, a nonsteroidal anti-inflammatory drug (NSAID), for pain relief in temporomandibular joint (TMJ) osteoarthritis or arthralgia.'?","No, the statement does not directly support that ibuprofen is related to arthralgia. Instead, it mentions that ibuprofen is used for pain relief in temporomandibular joint (TMJ) osteoarthritis or arthralgia as part of a study comparing it with palmitoylethanolamide (PEA)."
-14582794,Ibuprofen related to Pain,1030,"We investigated the analgesic efficacy of single doses of ibuprofen, tramadol and pregabalin in menthol-evoked cold pain in a randomized, placebo-controlled four-way cross-over study in 20 healthy volunteers.",False,"Is the triple 'Ibuprofen related to Pain' supported by the sentence: 'We investigated the analgesic efficacy of single doses of ibuprofen, tramadol and pregabalin in menthol-evoked cold pain in a randomized, placebo-controlled four-way cross-over study in 20 healthy volunteers.'?","No, it does not provide direct support for that statement because it does not mention any relationship between Ibuprofen and pain relief specifically in the context of pain caused by a particular condition, menthol-evoked cold pain in this case, but it does suggest that Ibuprofen has some degree of pain relieving properties as it was studied for its analgesic effects."
-11440746,Ibuprofen related to Toothache,1031,Double blind study on emorfazone and ibuprofen in dental pain and inflammation.,False,Is the triple 'Ibuprofen related to Toothache' supported by the sentence: 'Double blind study on emorfazone and ibuprofen in dental pain and inflammation.'?,"No, because the sentence mentions a double-blind study comparing emorfazone with ibuprofen for dental pain and inflammation, but it does not explicitly state that ibuprofen is related to toothache, nor does it state that there is a direct relationship between the two entities mentioned (emorfazone and ibuprofen)."
-9106384,Ibuprofen related to osteoarthritis,1032,Glucosamine sulfate compared to ibuprofen in osteoarthritis of the knee.,False,Is the triple 'Ibuprofen related to osteoarthritis' supported by the sentence: 'Glucosamine sulfate compared to ibuprofen in osteoarthritis of the knee.'?,"No, it is not directly supported because this statement compares glucosamine sulfate with ibuprofen in treating knee osteoarthritis, but it does not provide any information about a direct relationship between ibuprofen and osteoarthritis itself."
-8106985,Ibuprofen related to burn,1033,INTRODUCTION: The anti-inflammatory and anticoagulant effects of ibuprofen and heparin may enhance skin perfusion in cutaneous scald burns.,False,Is the triple 'Ibuprofen related to burn' supported by the sentence: 'INTRODUCTION: The anti-inflammatory and anticoagulant effects of ibuprofen and heparin may enhance skin perfusion in cutaneous scald burns.'?,"No, the statement does not directly support a direct relationship between ibuprofen and burns. It suggests that ibuprofen, due to its anti-inflammatory and anticoagulant effects, may potentially improve skin perfusion in cutaneous scald burns when used in conjunction with heparin. However, it does not explicitly state that ibuprofen is directly related to burns."
-13726345,Ibuprofen causes patent ductus arteriosus,1034,"CONCLUSIONS: Ibuprofen-induced patent ductus arteriosus closure improved pulmonary mechanics, decreased total lung water, increased epithelial sodium channel expression, and decreased the detrimental effects of preterm birth on alveolarization.",False,"Is the triple 'Ibuprofen causes patent ductus arteriosus' supported by the sentence: 'CONCLUSIONS: Ibuprofen-induced patent ductus arteriosus closure improved pulmonary mechanics, decreased total lung water, increased epithelial sodium channel expression, and decreased the detrimental effects of preterm birth on alveolarization.'?","No, it is not directly supported because this conclusion focuses on ibuprofen's role in closing patent ductus arteriosus (PDA) and its effects on pulmonary mechanics, lung water, epithelial sodium channel expression, and alveolarization in preterm births. It does not provide evidence that ibuprofen itself is a cause of PDA, but rather discusses its potential role in treating PDA in preterm infants."
-13653982,Ibuprofen causes Alzheimer disease,1035,Protein profile in neuroblastoma cells incubated with S- and R-enantiomers of ibuprofen by iTRAQ-coupled 2-D LC-MS/MS analysis: possible action of induced proteins on Alzheimer's disease.,False,Is the triple 'Ibuprofen causes Alzheimer disease' supported by the sentence: 'Protein profile in neuroblastoma cells incubated with S- and R-enantiomers of ibuprofen by iTRAQ-coupled 2-D LC-MS/MS analysis: possible action of induced proteins on Alzheimer's disease.'?,"No, this statement does not provide direct support for the claim that ibuprofen causes Alzheimer's disease. The study mentioned investigates the protein profile in neuroblastoma cells when exposed to ibuprofen, but it does not establish a causal relationship between ibuprofen and Alzheimer's disease."
-13133316,Ibuprofen causes peptic ulcer disease,1036,Protective effect of glucosamine against ibuprofen-induced peptic ulcer in rats.,False,Is the triple 'Ibuprofen causes peptic ulcer disease' supported by the sentence: 'Protective effect of glucosamine against ibuprofen-induced peptic ulcer in rats.'?,"No, it is not directly supported. The given sentence suggests that glucosamine has a protective effect against Ibuprofen-induced peptic ulcers in rats, but it does not confirm that Ibuprofen itself causes peptic ulcer disease in rats, let alone in humans."
-12641386,Ibuprofen causes Fever,1037,Ibuprofen-induced fever in Sjogren's syndrome.,False,Is the triple 'Ibuprofen causes Fever' supported by the sentence: 'Ibuprofen-induced fever in Sjogren's syndrome.'?,"No, it is not. The statement ""Ibuprofen-induced fever in Sjogren's syndrome"" does not directly support the claim that ""Ibuprofen causes fever"". The sentence you provided suggests that ibuprofen may induce a fever as a side effect in individuals with Sjogren's syndrome, not that it generally causes a fever in all individuals."
-12482174,Ibuprofen causes pancreatitis,1038,There have been no prior definite cases reported of ibuprofen-induced pancreatitis.,False,Is the triple 'Ibuprofen causes pancreatitis' supported by the sentence: 'There have been no prior definite cases reported of ibuprofen-induced pancreatitis.'?,"No, the statement ""There have been no prior definite cases reported of ibuprofen-induced pancreatitis."" does not support the claim that ""Ibuprofen causes pancreatitis."" In fact, it suggests the opposite, implying that there is no definitive evidence linking ibuprofen to pancreatitis."
-12438812,Ibuprofen causes Toothache,1039,"RESULTS: None of the studies established any of the COX-2 inhibitors as clearly better than ibuprofen, the current gold standard for the treatment of surgically induced dental pain.",False,"Is the triple 'Ibuprofen causes Toothache' supported by the sentence: 'RESULTS: None of the studies established any of the COX-2 inhibitors as clearly better than ibuprofen, the current gold standard for the treatment of surgically induced dental pain.'?","No, it is not directly supported because there is nothing in that statement indicating that ibuprofen can cause toothache."
-12079834,Ibuprofen causes adult acute respiratory distress syndrome,1040,Noncardiogenic pulmonary edema due to ibuprofen.,True,Is the triple 'Ibuprofen causes adult acute respiratory distress syndrome' supported by the sentence: 'Noncardiogenic pulmonary edema due to ibuprofen.'?,"Yes, the statement ""ibuprofen causes adult acute respiratory distress syndrome"" is indirectly supported by the sentence ""noncardiogenic pulmonary edema due to ibuprofen."" Acute respiratory distress syndrome (ARDS) can be a result of noncardiogenic pulmonary edema, which is one of the potential side effects of ibuprofen. However, it's important to note that this doesn't mean every person who takes ibuprofen will develop ARDS, as there are many factors that can contribute to its development."
-11157616,Ibuprofen causes Pain,1041,"In a double-blind cross-over study on 22 healthy subjects the analgesic efficacies of the antipyretic analgesic drugs ibuprofen, dipyrone and paracetamol were tested against placebo using a model of experimentally induced pain.",False,"Is the triple 'Ibuprofen causes Pain' supported by the sentence: 'In a double-blind cross-over study on 22 healthy subjects the analgesic efficacies of the antipyretic analgesic drugs ibuprofen, dipyrone and paracetamol were tested against placebo using a model of experimentally induced pain.'?","No, this statement does not provide direct support for the claim that Ibuprofen causes pain. In fact, it seems to suggest the opposite, as it mentions an experiment where ibuprofen was tested for its analgesic (pain relieving) efficacy against placebo using a model of experimentally induced pain."
-10429873,Ibuprofen causes Hemorrhage,1042,Unaltered ibuprofen-induced faecal blood loss upon coadministration of moclobemide.,False,Is the triple 'Ibuprofen causes Hemorrhage' supported by the sentence: 'Unaltered ibuprofen-induced faecal blood loss upon coadministration of moclobemide.'?,"No, it is not directly supported because the second statement does not explicitly mention hemorrhage, but rather refers to 'faecal blood loss'. While it might suggest a potential connection, it does not provide direct evidence for the claim that 'ibuprofen causes hemorrhage'."
-9800201,Ibuprofen causes arthritic joint disease,1043,The C5a antagonist (1 or 3 mg/kg/day) and/or ibuprofen (30 mg/kg/day) were administered orally on a daily basis either before or after arthritis induction.,False,Is the triple 'Ibuprofen causes arthritic joint disease' supported by the sentence: 'The C5a antagonist (1 or 3 mg/kg/day) and/or ibuprofen (30 mg/kg/day) were administered orally on a daily basis either before or after arthritis induction.'?,"No, this statement does not provide direct support for the claim that ibuprofen causes arthritic joint disease. In fact, it suggests that ibuprofen is being used as a treatment for arthritis, not as a cause."
-8163776,Ibuprofen causes injury,1044,RESULTS: Ketoprofen 50 mg t.d.s. suppressed prostaglandin synthesis to a significantly greater extent than ibuprofen and caused significantly more gastroduodenal injury.,True,Is the triple 'Ibuprofen causes injury' supported by the sentence: 'RESULTS: Ketoprofen 50 mg t.d.s. suppressed prostaglandin synthesis to a significantly greater extent than ibuprofen and caused significantly more gastroduodenal injury.'?,"Yes, the statement suggests that ketoprofen caused more gastroduodenal injury than ibuprofen, implying that ibuprofen may cause some level of gastroduodenal injury, but to a lesser extent than ketoprofen. However, it's important to note that this is an indirect inference, as the sentence does not explicitly state that ibuprofen causes injury."
-26701175,Ibuprofen affects rheumatoid arthritis,1045,The duration of action of sustained-release ibuprofen ('Brufen Retard') was investigated in a 14-day double-blind study involving 14 osteoarthritis and 10 rheumatoid arthritis patients.,False,Is the triple 'Ibuprofen affects rheumatoid arthritis' supported by the sentence: 'The duration of action of sustained-release ibuprofen ('Brufen Retard') was investigated in a 14-day double-blind study involving 14 osteoarthritis and 10 rheumatoid arthritis patients.'?,"No, this statement does not directly support that Ibuprofen affects rheumatoid arthritis. It talks about a study involving patients with osteoarthritis and rheumatoid arthritis, but it does not provide any information about how Ibuprofen specifically impacts rheumatoid arthritis."
-24384432,Ibuprofen affects migraine disorder,1046,This study attempts to investigate the effect of ibuprofen on reducing eye pain and migraine headaches caused by trochleitis.,False,Is the triple 'Ibuprofen affects migraine disorder' supported by the sentence: 'This study attempts to investigate the effect of ibuprofen on reducing eye pain and migraine headaches caused by trochleitis.'?,"No, it is not directly supported as this statement is about a specific investigation related to trochleitis, not a general investigation about all types of migraines caused by different factors."
-23500890,Ibuprofen affects adult acute respiratory distress syndrome,1047,"Ibuprofen suppresses the production of various pro-inflammatory cytokines that are implicated in the ""cytokine storm"" and subsequent ARDS in COVID-19 disease.",False,"Is the triple 'Ibuprofen affects adult acute respiratory distress syndrome' supported by the sentence: 'Ibuprofen suppresses the production of various pro-inflammatory cytokines that are implicated in the ""cytokine storm"" and subsequent ARDS in COVID-19 disease.'?","No, it is not directly supported. While both sentences discuss Ibuprofen's potential impact on inflammation, one does not explicitly state that it affects adult acute respiratory distress syndrome (ARDS). It would require additional evidence to make a direct correlation."
-21214366,Ibuprofen affects bronchopulmonary dysplasia,1048,"After adjusting for covariates, the risk of BPD was associated independently with ibuprofen exposure (odds ratios (OR) 2.296, 95% confidence interval (CI): 1.166-4.522, p = 0.016).",True,"Is the triple 'Ibuprofen affects bronchopulmonary dysplasia' supported by the sentence: 'After adjusting for covariates, the risk of BPD was associated independently with ibuprofen exposure (odds ratios (OR) 2.296, 95% confidence interval (CI): 1.166-4.522, p = 0.016).'?","Yes, the statement does support a relationship between ibuprofen exposure and bronchopulmonary dysplasia (BPD). The odds ratios (OR) 2.296 with a 95% confidence interval (CI): 1.166-4.522 indicate that there is a statistically significant association between ibuprofen exposure and BPD (p = 0.016). However, it's important to note that this does not necessarily imply direct causation, as other factors (covariates) may also be influencing this relationship."
-20886939,Ibuprofen affects Cognitive impairment,1049,The opposite effect of ibuprofen on ethanol-induced cognitive impairment as measured by two lateralized functions is consistent with the reports in tissue and animal models that central nervous system effects of ethanol may be mediated at least in part by prostaglandins.,False,Is the triple 'Ibuprofen affects Cognitive impairment' supported by the sentence: 'The opposite effect of ibuprofen on ethanol-induced cognitive impairment as measured by two lateralized functions is consistent with the reports in tissue and animal models that central nervous system effects of ethanol may be mediated at least in part by prostaglandins.'?,"No, it is not directly supported. This sentence discusses the role of prostaglandins in mediating central nervous system effects of ethanol, not specifically about cognitive impairment caused by Ibuprofen."
-12685801,Description treats Acute suppurative arthritis due to bacteria,2,"This is the first report of septic arthritis in humans caused by this microorganism, and the first description of B. vesicularis infection in an immunocompetent child.",False,"Is the triple 'Description treats Acute suppurative arthritis due to bacteria' supported by the sentence: 'This is the first report of septic arthritis in humans caused by this microorganism, and the first description of B. vesicularis infection in an immunocompetent child.'?","No, it is not directly supported. The given sentence discusses a case report of a child with an infection caused by B. vesicularis, which led to septic arthritis, but it does not provide a detailed description of acute suppurative arthritis caused by this bacterium."
-27481671,Provider treats Chronic pain,3,"Health providers continue to search for ways to explain, predict, and cure the misery caused by chronic pain.",False,"Is the triple 'Provider treats Chronic pain' supported by the sentence: 'Health providers continue to search for ways to explain, predict, and cure the misery caused by chronic pain.'?","No, it is not directly supported because while both sentences discuss chronic pain and healthcare providers, they do not make a direct connection between healthcare providers treating chronic pain with a specific focus on curing it (triple 'Provider treats Chronic Pain'). The second sentence discusses healthcare providers seeking explanations, predictions, and cures for chronic pain in general."
-19423160,Provider treats Sepsis,4,The objective of this review is to determine the effectiveness of provider strategies for the early recognition of clinical deterioration due to sepsis in pediatric patients.,False,Is the triple 'Provider treats Sepsis' supported by the sentence: 'The objective of this review is to determine the effectiveness of provider strategies for the early recognition of clinical deterioration due to sepsis in pediatric patients.'?,"No, it does not seem that way. The given statement discusses determining the effectiveness of 'provider strategies' in recognizing pediatric sepsis, but it does not explicitly state that 'provider treats sepsis' as an outcome."
-18994076,Provider treats transient ischemic attack,5,CONCLUSIONS: Primary and emergency care providers need to review how they can best handle patients presenting with symptoms that could be due to stroke or TIA.,False,Is the triple 'Provider treats transient ischemic attack' supported by the sentence: 'CONCLUSIONS: Primary and emergency care providers need to review how they can best handle patients presenting with symptoms that could be due to stroke or TIA.'?,"No, it is not directly supported because the sentence does not specifically mention a provider treating a transient ischemic attack (TIA), but rather suggests that primary and emergency care providers should improve their handling of patients who present with symptoms that could be due to stroke or TIA."
-18980233,Provider treats obesity disorder,6,"Progress notes were examined to extract need for weight management (WM), patient-provider discussions about risk due to overweight/obesity, recommended lifestyle changes and/or follow-up and WM education.",False,"Is the triple 'Provider treats obesity disorder' supported by the sentence: 'Progress notes were examined to extract need for weight management (WM), patient-provider discussions about risk due to overweight/obesity, recommended lifestyle changes and/or follow-up and WM education.'?","No, it is not directly supported. The given sentence discusses the examination of progress notes to gather information on various aspects of managing overweight/obesity, but it does not explicitly state that a provider is treating an obesity disorder as a result of these actions."
-17192662,Provider treats osteoarthritis,7,"CONCLUSION: Training rural providers to perform knee injections for patients with knee pain secondary to osteoarthritis appears cost effective using the commonly used threshold of $50,000/QALY if more than 20 such patients per year are seen at rural primary care clinics.",False,"Is the triple 'Provider treats osteoarthritis' supported by the sentence: 'CONCLUSION: Training rural providers to perform knee injections for patients with knee pain secondary to osteoarthritis appears cost effective using the commonly used threshold of $50,000/QALY if more than 20 such patients per year are seen at rural primary care clinics.'?","No, it is not directly supported. The conclusion supports that training primary care clinics' providers to administer knee injections is cost-effective, but it does not explicitly state that this treatment is specifically for osteoarthritis, even though it is implied due to mentioning pain secondary to it."
-16604884,Provider treats cerebral palsy,8,"This article describes the results of surveys completed by disability service providers and individuals with CCN due to cerebral palsy, developmental delay, and acquired disabilities.",False,"Is the triple 'Provider treats cerebral palsy' supported by the sentence: 'This article describes the results of surveys completed by disability service providers and individuals with CCN due to cerebral palsy, developmental delay, and acquired disabilities.'?","No, it is not directly supported by the given sentence. The sentence discusses a study involving survey responses from both disability service providers and individuals affected by various disabilities, including cerebral palsy, developmental delay, and acquired disabilities, but it does not explicitly state that a provider treats cerebral palsy."
-15941387,Provider treats Rotavirus infection,9,"We estimated health provider costs, economic costs and quality-adjusted life years (QALYs) lost due to rotavirus infections.",False,"Is the triple 'Provider treats Rotavirus infection' supported by the sentence: 'We estimated health provider costs, economic costs and quality-adjusted life years (QALYs) lost due to rotavirus infections.'?",No. The provided sentence discusses estimating various costs and QALYs lost due to rotavirus infections but it does not explicitly mention that a healthcare provider specifically treats rotavirus infections.
-14457077,Provider treats Fatigue,10,"It seems reasonable to alternate chest compression providers every 2 min, to prevent the loss of effective compressions due to fatigue and to minimise interruptions of chest compressions.",True,"Is the triple 'Provider treats Fatigue' supported by the sentence: 'It seems reasonable to alternate chest compression providers every 2 min, to prevent the loss of effective compressions due to fatigue and to minimise interruptions of chest compressions.'?","Yes, the triple ""Provider treats Fatigue"" is indirectly supported by the given sentence. It suggests that alternating chest compression providers can help mitigate fatigue-related losses in effectiveness and minimize interruptions in CPR, implying that fatigue is a concern that needs addressing through provider rotation."
-13583178,Provider treats stroke disorder,11,"Thus, families must increasingly partner with health service providers to promote their child's health and prevent the development of secondary conditions that may contribute to heart disease, stroke, respiratory diseases, low endurance and emotional difficulties.",False,"Is the triple 'Provider treats stroke disorder' supported by the sentence: 'Thus, families must increasingly partner with health service providers to promote their child's health and prevent the development of secondary conditions that may contribute to heart disease, stroke, respiratory diseases, low endurance and emotional difficulties.'?","No, it is not directly supported. The mentioned secondary conditions that may contribute to heart disease, respiratory diseases, low endurance and emotional difficulties do not explicitly include stroke disorder in this context."
-13583177,Provider treats respiratory system disorder,12,"Thus, families must increasingly partner with health service providers to promote their child's health and prevent the development of secondary conditions that may contribute to heart disease, stroke, respiratory diseases, low endurance and emotional difficulties.",False,"Is the triple 'Provider treats respiratory system disorder' supported by the sentence: 'Thus, families must increasingly partner with health service providers to promote their child's health and prevent the development of secondary conditions that may contribute to heart disease, stroke, respiratory diseases, low endurance and emotional difficulties.'?","No, the sentence does not directly support the statement that a provider specifically treats a respiratory system disorder. It suggests that families should work with healthcare providers to prevent conditions that may contribute to respiratory diseases, among other things."
-13583176,Provider treats heart disorder,13,"Thus, families must increasingly partner with health service providers to promote their child's health and prevent the development of secondary conditions that may contribute to heart disease, stroke, respiratory diseases, low endurance and emotional difficulties.",False,"Is the triple 'Provider treats heart disorder' supported by the sentence: 'Thus, families must increasingly partner with health service providers to promote their child's health and prevent the development of secondary conditions that may contribute to heart disease, stroke, respiratory diseases, low endurance and emotional difficulties.'?","No. The provided sentence discusses the role of families in partnership with health service providers for preventing secondary conditions that contribute to various diseases including those affecting the heart. However, it does not explicitly state that a provider treats a specific heart disorder."
-13436217,Provider treats asthma,14,"CAEs often advised callers (> 75%) to return to their asthma provider for assistance as a result of uncontrolled asthma, medication concerns, a questionable diagnosis, or the need for an action plan.",False,"Is the triple 'Provider treats asthma' supported by the sentence: 'CAEs often advised callers (> 75%) to return to their asthma provider for assistance as a result of uncontrolled asthma, medication concerns, a questionable diagnosis, or the need for an action plan.'?","No, the statement ""Provider treats asthma"" is not explicitly mentioned in the provided sentence about Certified Asthma Educators advising callers with uncontrolled asthma, medication concerns, questionable diagnosis, or need for an action plan."
-13417890,Provider treats Pain,15,"Reasons include: inflexibility by dialysis providers because of reduced profitability, claims that patients oppose the subcutaneous route because of pain at the site of injection, concerns regarding pure red cell aplasia associated with subcutaneous administration, and greater hemoglobin cycling with the subcutaneous route.",False,"Is the triple 'Provider treats Pain' supported by the sentence: 'Reasons include: inflexibility by dialysis providers because of reduced profitability, claims that patients oppose the subcutaneous route because of pain at the site of injection, concerns regarding pure red cell aplasia associated with subcutaneous administration, and greater hemoglobin cycling with the subcutaneous route.'?","No. The statement mentions reasons why there is resistance to subcutaneous administration due to pain at injection site, but it does not explicitly connect this to a provider treating pain as a primary outcome."
-26452787,Fenbendazole treats infectious disease,16,Fenbendazole was effective against induced infections of A tubaeforme and Taen taeniaeformis.,False,Is the triple 'Fenbendazole treats infectious disease' supported by the sentence: 'Fenbendazole was effective against induced infections of A tubaeforme and Taen taeniaeformis.'?,"No, it is not directly supported because the original statement discusses Fenbendazole's effectiveness on specific organisms (A tubaeforme and Taen taeniaeformis), whereas the triple statement generalizes it to all infectious diseases, which is not explicitly stated nor implied in the original statement."
-26452786,Fenbendazole treats helminthiasis,17,Evaluation of granulated fenbendazole (22.2%) against induced and naturally occurring helminth infections in cats.,True,Is the triple 'Fenbendazole treats helminthiasis' supported by the sentence: 'Evaluation of granulated fenbendazole (22.2%) against induced and naturally occurring helminth infections in cats.'?,"Yes, the statement ""Fenbendazole treats helminthiasis"" is indirectly supported by the provided sentence. The phrase ""granulated fenbendazole (22.2%) against induced and naturally occurring helminth infections in cats"" implies that Fenbendazole is used to treat helminth infections in cats, which is what 'helminthiasis' refers to. However, it's important to note that this is an indirect inference, as the original sentence does not explicitly state that Fenbendazole 'treats' helminthiasis, but rather that it is used against it."
-25044562,Fenbendazole treats Intestinal nematode infection,18,"Efficacy of dichlorvos, fenbendazole, and ivermectin in swine with induced intestinal nematode infections.",False,"Is the triple 'Fenbendazole treats Intestinal nematode infection' supported by the sentence: 'Efficacy of dichlorvos, fenbendazole, and ivermectin in swine with induced intestinal nematode infections.'?","No, it is not directly supported by that sentence alone. The statement mentions that Fenbendazole is used in swine with induced intestinal nematode infections but it doesn't explicitly state that Fenbendazole is used to treat intestinal nematode infections in general."
-24521403,Fenbendazole treats Increased reactive oxygen species production,19,"Furthermore, we explored the associated mechanism, and our results showed that analog 6 and fenbendazole could induce oxidative stress by accumulating ROS.",True,"Is the triple 'Fenbendazole treats Increased reactive oxygen species production' supported by the sentence: 'Furthermore, we explored the associated mechanism, and our results showed that analog 6 and fenbendazole could induce oxidative stress by accumulating ROS.'?","Yes, it is indirectly supported as both statements discuss a relationship between Fenbendazole and increased reactive oxygen species (ROS) production, implying a potential treatment role for Fenbendazole in managing oxidative stress. However, it does not explicitly state that Fenbendazole directly treats increased ROS production."
-23706249,Fenbendazole treats Adverse reactions,20,"However, it is known that administration of high, off-label doses of fenbendazole can lead to adverse reactions.",False,"Is the triple 'Fenbendazole treats Adverse reactions' supported by the sentence: 'However, it is known that administration of high, off-label doses of fenbendazole can lead to adverse reactions.'?","No, they are not directly supported by each other. The first statement mentions treating adverse reactions with Fenbendazole, while the second statement discusses adverse reactions as a consequence of administering high doses of Fenbendazole."
-19012088,Fenbendazole treats Immune response,21,Effect of fenbendazole and pyrantel tartrate on the induction of protective immunity in pigs naturally or experimentally infected with Ascaris suum.,False,Is the triple 'Fenbendazole treats Immune response' supported by the sentence: 'Effect of fenbendazole and pyrantel tartrate on the induction of protective immunity in pigs naturally or experimentally infected with Ascaris suum.'?,"No, the statement 'Fenbendazole treats immune response' is not directly supported by the given title 'Effect of Fenbendazole and Pyrantel Tartrate on the Induction of Protective Immunity in Pigs Naturally or Experimentally Infected with Ascaris suum'. The title discusses the impact of Fenbendazole on immunity induction in pigs infected with a specific parasite, not its direct effect on immune response."
-16366394,Fenbendazole treats Apoptosis,22,"This is the first report to demonstrate the inhibition of proteasome function and induction of endoplasmic reticulum stress/reactive oxygen species-dependent apoptosis in human lung cancer cell lines by fenbendazole, which may represent a new class of anticancer agents showing selective toxicity against cancer cells.",True,"Is the triple 'Fenbendazole treats Apoptosis' supported by the sentence: 'This is the first report to demonstrate the inhibition of proteasome function and induction of endoplasmic reticulum stress/reactive oxygen species-dependent apoptosis in human lung cancer cell lines by fenbendazole, which may represent a new class of anticancer agents showing selective toxicity against cancer cells.'?","Yes, the statement ""Fenbendazole treats Apoptosis"" is indirectly supported by this sentence, as it mentions that fenbendazole induces apoptosis in human lung cancer cell lines, which implies that it could potentially be used as a treatment for apoptosis in this context. However, it's important to note that this statement is a simplification and further research would be needed to confirm this potential use in a clinical setting."
-27756813,mebendazole treats granulomatous hepatitis,23,Granulomatous hepatitis due to mebendazole.,True,Is the triple 'mebendazole treats granulomatous hepatitis' supported by the sentence: 'Granulomatous hepatitis due to mebendazole.'?,"Yes, the statement ""mebendazole treats granulomatous hepatitis"" is indirectly supported by the sentence ""Granulomatous hepatitis due to mebendazole."" This is because it indicates that mebendazole can cause granulomatous hepatitis, which suggests that treating with mebendazole could be a way to manage this condition, although it doesn't explicitly state that mebendazole is used to treat this condition. However, it's important to note that medical treatments should always be based on thorough research, professional medical advice, and a comprehensive understanding of the patient's condition."
-27730862,mebendazole treats Cytoplasmic Alteration,24,The cellular changes documented are likely to account for previously described cytoplasmic alterations induced by MBZ.,True,Is the triple 'mebendazole treats Cytoplasmic Alteration' supported by the sentence: 'The cellular changes documented are likely to account for previously described cytoplasmic alterations induced by MBZ.'?,"Yes, it is indirectly supported. The given statement suggests that mebendazole (MBZ) induces cytoplasmic alterations, which aligns with the claim that mebendazole treats cytoplasmic alterations, as treatment often involves reversing or managing the condition. However, it does not directly state that mebendazole is used to treat such alterations, hence it's an indirect support."
-26407395,mebendazole treats infectious disease,25,"A formulation of mebendazole was used to determine the optimal dosage level against induced and/or naturally occurring infections of Toxocara cati, Ancylostoma tubaeforme, and Taenia taeniaeformis in cats.",False,"Is the triple 'mebendazole treats infectious disease' supported by the sentence: 'A formulation of mebendazole was used to determine the optimal dosage level against induced and/or naturally occurring infections of Toxocara cati, Ancylostoma tubaeforme, and Taenia taeniaeformis in cats.'?","No, it is not directly supported because while it mentions that a formulation of mebendazole is used against certain infections in cats, it does not explicitly state that mebendazole treats those infections, nor does it specify that they are infectious diseases."
-26407394,mebendazole treats helminthiasis,26,Anthelmintic activity of mebendazole against induced and naturally occurring helminth infections in cats.,True,Is the triple 'mebendazole treats helminthiasis' supported by the sentence: 'Anthelmintic activity of mebendazole against induced and naturally occurring helminth infections in cats.'?,"Yes, the statement 'Mebendazole treats helminthiasis' is indirectly supported by the provided sentence. This is because the anthelmintic activity of a drug like mebendazole refers to its ability to treat helminthiasis, which is a type of infection caused by parasitic worms (helminths). However, it's important to note that direct support would require a statement explicitly mentioning 'treats' or 'therapy'."
-26245282,mebendazole treats Sedentary,27,"The effects are not rapid, however, for only mebendazole at 500 micrograms/ml treats total inactivity of the fluke within a 12-hr period.",False,"Is the triple 'mebendazole treats Sedentary' supported by the sentence: 'The effects are not rapid, however, for only mebendazole at 500 micrograms/ml treats total inactivity of the fluke within a 12-hr period.'?","No. The given sentence mentions that mebendazole at a specific concentration (500 micrograms/ml) can treat total inactivity of a specific organism (the fluke) within a certain time frame (a 12-hour period). However, it does not provide information about whether mebendazole can treat sedentary behavior in general. Therefore, it does not directly support the statement that mebendazole treats sedentary behavior."
-24434072,mebendazole treats Vascular System Injuries,28,Mebendazole-Induced Blood-Testis Barrier Injury in Mice Testes by Disrupting Microtubules in Addition to Triggering Programmed Cell Death.,False,Is the triple 'mebendazole treats Vascular System Injuries' supported by the sentence: 'Mebendazole-Induced Blood-Testis Barrier Injury in Mice Testes by Disrupting Microtubules in Addition to Triggering Programmed Cell Death.'?,"No, it is not. The given statement discusses mebendazole's effect on the blood-testis barrier, not on vascular system injuries."
-23551876,mebendazole treats Inflammation,29,"Using early models of pancreatic cancer, treatment with mebendazole resulted in less inflammation, decreased dysplasia, with the later stage model additionally showing a decreased tumor burden, less advanced tumors, and a reduction of metastasis.",False,"Is the triple 'mebendazole treats Inflammation' supported by the sentence: 'Using early models of pancreatic cancer, treatment with mebendazole resulted in less inflammation, decreased dysplasia, with the later stage model additionally showing a decreased tumor burden, less advanced tumors, and a reduction of metastasis.'?","No. The given sentence supports that mebendazole can decrease inflammation in a model of pancreatic cancer, but it does not directly support that mebendazole treats inflammation as a general condition outside of this specific context."
-23464334,mebendazole treats Cancer-Related Death,30,"CONCLUSION: Mebendazole and albendazole were shown to cause selective cancer cell death via a mechanism of classical apoptosis and cell cycle arrest, involving the destabilisation of microtubules.",False,"Is the triple 'mebendazole treats Cancer-Related Death' supported by the sentence: 'CONCLUSION: Mebendazole and albendazole were shown to cause selective cancer cell death via a mechanism of classical apoptosis and cell cycle arrest, involving the destabilisation of microtubules.'?","No, it is not directly supported, as this statement discusses how mebendazole causes cancer cell death, but does not mention anything about treating cancer-related deaths specifically."
-21460286,mebendazole treats Increased Apoptosis,31,"CONCLUSIONS: Docetaxel and mebendazole target distinct aspects of the microtubule dynamics, leading to increased apoptosis and reduced tumour growth.",True,"Is the triple 'mebendazole treats Increased Apoptosis' supported by the sentence: 'CONCLUSIONS: Docetaxel and mebendazole target distinct aspects of the microtubule dynamics, leading to increased apoptosis and reduced tumour growth.'?","Yes, the statement is indirectly supported, as it suggests that both docetaxel and mebendazole increase apoptosis, but it does not explicitly state that mebendazole increases apoptosis on its own, nor that it specifically targets increased apoptosis."
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+26452786,Fenbendazole causes helminthiasis,1001,Evaluation of granulated fenbendazole (22.2%) against induced and naturally occurring helminth infections in cats.,False,Is the triple 'Fenbendazole causes helminthiasis' supported by the sentence: 'Evaluation of granulated fenbendazole (22.2%) against induced and naturally occurring helminth infections in cats.'?,"No, the statement 'Fenbendazole causes helminthiasis' is not supported by the given sentence. In fact, it contradicts it, as it suggests that Fenbendazole is used to treat helminth infections (helminthiasis) in cats, not cause them."
+24413653,Fenbendazole treats helminthiasis,1002,"This study investigated worm control practices by free-range egg farmers and the efficacy of the commercial anthelmintics levamisole (LEV), piperazine (PIP), flubendazole (FLBZ) and fenbendazole (FBZ) against gastrointestinal nematodes on two free-range layer farms in Australia.",True,"Is the triple 'Fenbendazole treats helminthiasis' supported by the sentence: 'This study investigated worm control practices by free-range egg farmers and the efficacy of the commercial anthelmintics levamisole (LEV), piperazine (PIP), flubendazole (FLBZ) and fenbendazole (FBZ) against gastrointestinal nematodes on two free-range layer farms in Australia.'?","Yes, the statement is indirectly supported because it mentions that fenbendazole (FBZ) was part of a study investigating its efficacy against gastrointestinal nematodes on two free-range layer farms in Australia, which implies it can be used to treat helminthiasis (a parasitic disease caused by various intestinal worms)."
+22762728,Fenbendazole prevents helminthiasis,1003,Fenbendazole resistance in O. ostertagi was confirmed with a total treatment failure in reducing worm burden: efficacy of 0%.,False,Is the triple 'Fenbendazole prevents helminthiasis' supported by the sentence: 'Fenbendazole resistance in O. ostertagi was confirmed with a total treatment failure in reducing worm burden: efficacy of 0%.'?,"No, it is not directly or indirectly supported. The given sentence discusses a case of treatment failure with Fenbendazole, which suggests that Fenbendazole did not prevent helminthiasis (helminth infection) in this particular instance, but rather failed to reduce worm burden, which is a different aspect from prevention."
+9783282,Thiabendazole treats helminthiasis,1004,[The treatment of helminthiasis with thiabendazole].,True,Is the triple 'Thiabendazole treats helminthiasis' supported by the sentence: '[The treatment of helminthiasis with thiabendazole].'?,"Yes, it is indirectly supported because thiabendazole is mentioned as a treatment for helminthiasis in your provided sentence, which aligns with the statement that thiabendazole treats helminthiasis, though not explicitly stated in your provided sentence."
+21848143,Albendazole causes helminthiasis,1005,Symptoms of perianal itching and visualization of visible motile worms persisted for 6 months despite being treated with multiple courses of albendazole causing a lot of frustration and distress to the caregivers.,False,Is the triple 'Albendazole causes helminthiasis' supported by the sentence: 'Symptoms of perianal itching and visualization of visible motile worms persisted for 6 months despite being treated with multiple courses of albendazole causing a lot of frustration and distress to the caregivers.'?,"No, the statement does not support the idea that albendazole causes helminthiasis (a condition characterized by parasitic worm infestations). In fact, it suggests the opposite: that albendazole was used as a treatment for helminthiasis, but was not successful in eliminating the symptoms in this particular case."
+25735916,Albendazole affects trichuriasis,1006,"Ovicidal effects of albendazole in human ascariasis, ancylostomiasis and trichuriasis.",True,"Is the triple 'Albendazole affects trichuriasis' supported by the sentence: 'Ovicidal effects of albendazole in human ascariasis, ancylostomiasis and trichuriasis.'?","Yes, the triple ""Albendazole affects trichuriasis"" is directly supported by the given sentence as it mentions that Albendazole has ovicidal effects in trichuriasis, which implies that it does affect it."
+24685635,Albendazole affects filarial elephantiasis,1007,"A combination of drugs Ivermectin, Diethylcarbamazine citrate and Albendazole is recommended by WHO to accelerate the Global Programme to Eliminate Lymphatic Filariasis (GPELF).",True,"Is the triple 'Albendazole affects filarial elephantiasis' supported by the sentence: 'A combination of drugs Ivermectin, Diethylcarbamazine citrate and Albendazole is recommended by WHO to accelerate the Global Programme to Eliminate Lymphatic Filariasis (GPELF).'?","Yes, it is indirectly supported because while the sentence does not explicitly state that Albendazole affects filarial elephantiasis, it does mention that Albendazole is part of a recommended treatment for lymphatic filariasis, a condition that can lead to elephantiasis if left untreated."
+18452252,Albendazole affects toxocariasis,1008,Effect of albendazole in experimental toxocariasis of mice.,True,Is the triple 'Albendazole affects toxocariasis' supported by the sentence: 'Effect of albendazole in experimental toxocariasis of mice.'?,"Yes, the triple ""Albendazole affects toxocariasis"" is indirectly supported by the sentence: ""Effect of albendazole in experimental toxocariasis of mice."" This is because the sentence suggests that albendazole has an effect on an experiment related to toxocariasis, implying a potential relationship between the drug and the condition. However, a direct relationship is not explicitly stated in this sentence alone, hence it's an indirect support."
+16658505,Albendazole affects malaria,1009,"Given the low helminth prevalence in our children, the effect of albendazole on malaria is likely to be direct.",True,"Is the triple 'Albendazole affects malaria' supported by the sentence: 'Given the low helminth prevalence in our children, the effect of albendazole on malaria is likely to be direct.'?","Yes, it is indirectly supported. The sentence suggests that since there is a low prevalence of helminths (parasitic worms) among the studied children, administering albendazole (a medication used for treating certain worm infestations) would likely have a direct effect on reducing these worms. This could then potentially have an indirect effect on reducing malaria, as some studies have suggested that certain types of worm infestations might offer some protection against severe malaria symptoms. However, it's important to note that this is an interpretation based on the given sentence; for a more definitive conclusion, one would need to examine the full study or research findings."
+13946207,Albendazole affects helminthiasis,1010,"Mass co-administration of ivermectin and albendazole by the LFEP had a significant effect on STH, which was further amplified by treatment with praziquantel and albendazole 4 months later.",True,"Is the triple 'Albendazole affects helminthiasis' supported by the sentence: 'Mass co-administration of ivermectin and albendazole by the LFEP had a significant effect on STH, which was further amplified by treatment with praziquantel and albendazole 4 months later.'?","Yes, it is indirectly supported. The sentence mentions that mass co-administration of ivermectin and albendazole had a significant effect on Soil Transmitted Helminths (STH), which suggests that albendazole, as part of this treatment, does affect helminthiasis (a condition caused by STH). However, it doesn't explicitly state that albendazole alone has an effect on helminthiasis, which is why it's an indirect support."
+11239060,Albendazole affects filariasis,1011,The effect of single dose ivermectin alone or in combination with albendazole on Wuchereria bancrofti infection in primary school children in Tanzania.,False,Is the triple 'Albendazole affects filariasis' supported by the sentence: 'The effect of single dose ivermectin alone or in combination with albendazole on Wuchereria bancrofti infection in primary school children in Tanzania.'?,"No, the statement does not directly support the triple ""Albendazole affects filariasis"". The study mentioned focuses on the impact of Ivermectin, either used alone or in combination with Albendazole, on Wuchereria bancrofti infection in primary school children in Tanzania, rather than explicitly demonstrating Albendazole's direct effects on filariasis."
+22678969,Albendazole treats Infection,1012,The control of STH infections is based on preventive chemotherapy using either albendazole or mebendazole.,True,Is the triple 'Albendazole treats Infection' supported by the sentence: 'The control of STH infections is based on preventive chemotherapy using either albendazole or mebendazole.'?,"Yes, it is indirectly supported because both albendazole and mebendazole are mentioned as treatments for Soil-transmitted Helminth (STH) infections, implying that albendazole can treat such infections."
+10750815,Albendazole treats onchocerciasis,1013,"A double-blind clinical trial was conducted in Monagas State, Venezuela to assess the tolerance and efficacy of albendazole in the therapy of Onchocerca volvulus infection.",True,"Is the triple 'Albendazole treats onchocerciasis' supported by the sentence: 'A double-blind clinical trial was conducted in Monagas State, Venezuela to assess the tolerance and efficacy of albendazole in the therapy of Onchocerca volvulus infection.'?","Yes, it is indirectly supported because the statement describes a scientific study assessing albendazole's efficacy in treating Onchocerca volvulus infection, which is another term for onchocerciasis."
+10114050,Albendazole treats toxocariasis,1014,"The treatment of cutaneous larva migrans and Toxocara infection relies on antihelminthic agents such as thiabendazole, albendazole and ivermectin.",True,"Is the triple 'Albendazole treats toxocariasis' supported by the sentence: 'The treatment of cutaneous larva migrans and Toxocara infection relies on antihelminthic agents such as thiabendazole, albendazole and ivermectin.'?","Yes, the statement is indirectly supporting that Albendazole can treat Toxocara infection (toxocariasis), as it is listed as an antihelminthic agent effective for such infections, along with thiabendazole and ivermectin, according to your provided sentence."
+9588560,Albendazole treats trichuriasis,1015,"Three randomized clinical studies were conducted in 2000 to evaluate the efficacy of nitazoxanide paediatric suspension compared to albendazole in the treatment of ascariasis and trichuriasis and praziquantel in the treatment of hymenolepiasis in children from Cajamarca, Peru.",True,"Is the triple 'Albendazole treats trichuriasis' supported by the sentence: 'Three randomized clinical studies were conducted in 2000 to evaluate the efficacy of nitazoxanide paediatric suspension compared to albendazole in the treatment of ascariasis and trichuriasis and praziquantel in the treatment of hymenolepiasis in children from Cajamarca, Peru.'?","Yes, it is indirectly supported because the statement mentions a study involving albendazole for treating trichuriasis, although it does not explicitly state that albendazole is effective for treating trichuriasis, it suggests that it was used for that purpose in a scientific study."
+9492446,Albendazole treats filariasis,1016,"Today, the only way is the prophylactic control of Onchocerca vovulus infections and treating lymphatic filariosis with ivermectin, diethylcarbamacine, ivermectin/diethylcarbamazine. or ivermectin/albendazole combinations.",True,"Is the triple 'Albendazole treats filariasis' supported by the sentence: 'Today, the only way is the prophylactic control of Onchocerca vovulus infections and treating lymphatic filariosis with ivermectin, diethylcarbamacine, ivermectin/diethylcarbamazine. or ivermectin/albendazole combinations.'?","Yes, it is indirectly supported because albendazole is mentioned as a component in a treatment combination for lymphatic filariosis (which includes filariasis). However, it's important to note that albendazole alone does not treat filariasis; it's used in combination with other drugs for this purpose."
+8712067,Albendazole treats helminthiasis,1017,The study population was assessed for helminthic infection and those found to be positive were randomly assigned to either an albendazole treatment group or a control group who received a placebo.,True,Is the triple 'Albendazole treats helminthiasis' supported by the sentence: 'The study population was assessed for helminthic infection and those found to be positive were randomly assigned to either an albendazole treatment group or a control group who received a placebo.'?,"Yes, it is indirectly supported because the statement mentions that individuals with a positive diagnosis of helminthic infection were given albendazole, implying that albendazole is used to treat helminthiasis, which is a condition caused by helminths, a type of parasitic worm."
+7789677,Albendazole treats strongyloidiasis,1018,"To determine the host factors involved in response to treatment, 46 patients with strongyloidiasis were treated with albendazole, followed-up for 1 year, and separated into two groups: cured and non-cured.",False,"Is the triple 'Albendazole treats strongyloidiasis' supported by the sentence: 'To determine the host factors involved in response to treatment, 46 patients with strongyloidiasis were treated with albendazole, followed-up for 1 year, and separated into two groups: cured and non-cured.'?","No, it is not directly supported because it does not explicitly state that Albendazole cures strongyloidiasis, but it does provide evidence that it is used as a treatment for strongyloidiasis, making it indirectly supportive."
+7640018,Albendazole treats filarial elephantiasis,1019,The role of albendazole in programmes to eliminate lymphatic filariasis.,True,Is the triple 'Albendazole treats filarial elephantiasis' supported by the sentence: 'The role of albendazole in programmes to eliminate lymphatic filariasis.'?,"Yes, it is indirectly supported. The given sentence suggests that Albendazole is used in programs to eliminate lymphatic filariasis, which is a type of filarial elephantiasis."
+7620262,Albendazole treats Hookworm Infections,1020,On the basis of our results the single 400 mg dose of albendazole is the treatment of choice for hookworm infections in this region of Mali.,True,Is the triple 'Albendazole treats Hookworm Infections' supported by the sentence: 'On the basis of our results the single 400 mg dose of albendazole is the treatment of choice for hookworm infections in this region of Mali.'?,"Yes, the statement ""Albendazole treats Hookworm Infections"" is indirectly supported by your provided sentence, as it suggests that a single dose of Albendazole is an effective treatment for hookworm infections in a specific region, implying that Albendazole has some effect on hookworm infections generally."
+7226097,Albendazole treats cysticercosis,1021,The efficacy of albendazole (15 mg/kg/d for 1 week) was compared with praziquantel (100 mg/kg in three divided doses at 2-hour intervals) for therapy of parenchymal brain cysticercosis.,False,Is the triple 'Albendazole treats cysticercosis' supported by the sentence: 'The efficacy of albendazole (15 mg/kg/d for 1 week) was compared with praziquantel (100 mg/kg in three divided doses at 2-hour intervals) for therapy of parenchymal brain cysticercosis.'?,"No, it is not directly supported because the given sentence does not mention that Albendazole treats cysticercosis, but it does provide evidence that Albendazole is used in the treatment of parenchymal brain cysticercosis, which is a form of cysticercosis."
+24729219,Albendazole disrupts helminthiasis,1022,"Additionally, compared with albendazole, it resulted in a significant reduction in adult worm and total larval counts; moreover, it caused a decrease in the number of larvae deposited in muscles, with a highly significant decrease in the inflammatory cell infiltrate around the larvae and a considerable decrease in the expression of the angiogenic marker vascular endothelial growth factor in muscles.",True,"Is the triple 'Albendazole disrupts helminthiasis' supported by the sentence: 'Additionally, compared with albendazole, it resulted in a significant reduction in adult worm and total larval counts; moreover, it caused a decrease in the number of larvae deposited in muscles, with a highly significant decrease in the inflammatory cell infiltrate around the larvae and a considerable decrease in the expression of the angiogenic marker vascular endothelial growth factor in muscles.'?","Yes, the triple statement is indirectly supported by this sentence as it suggests that Albendazole has an impact on adult worm counts, larval counts, larvae deposits in muscles, inflammatory cell infiltrate around larvae, and expression of vascular endothelial growth factor in muscles which could all be indicative of its disruption of helminthiasis. However, it does not explicitly state that Albendazole disrupts helminthiasis."
+16658503,Albendazole disrupts malaria,1023,"Quarterly albendazole during childhood was associated with reduced incidence of clinical malaria (HR 0.85 (95% CI 0.73-0.98), p = 0.03).",True,"Is the triple 'Albendazole disrupts malaria' supported by the sentence: 'Quarterly albendazole during childhood was associated with reduced incidence of clinical malaria (HR 0.85 (95% CI 0.73-0.98), p = 0.03).'?","Yes, the statement does provide indirect support to the idea that Albendazole may disrupt malaria, as it suggests a correlation between taking Albendazole and a reduced incidence of clinical malaria. However, it does not directly state that Albendazole disrupts malaria, as it implies a preventative effect rather than a disruptive one."
+13637338,Albendazole disrupts Hookworm Infections,1024,CONCLUSIONS: Mebendazole and albendazole showed reduced efficacy against Ascaris lumbricoides and hookworm infections at the recommended doses.,True,Is the triple 'Albendazole disrupts Hookworm Infections' supported by the sentence: 'CONCLUSIONS: Mebendazole and albendazole showed reduced efficacy against Ascaris lumbricoides and hookworm infections at the recommended doses.'?,"Yes, it is indirectly supported because the sentence mentions that albendazole showed reduced efficacy against hookworm infections, which aligns with the idea that albendazole disrupts hookworm infections, but it does not explicitly state that albendazole disrupts hookworm infections."
+15248433,Albendazole prevents filariasis,1025,Evaluation of effectiveness of diethylcarbamazine/albendazole combination in reduction of Wuchereria bancrofti infection using multiple infection parameters.,False,Is the triple 'Albendazole prevents filariasis' supported by the sentence: 'Evaluation of effectiveness of diethylcarbamazine/albendazole combination in reduction of Wuchereria bancrofti infection using multiple infection parameters.'?,"No, it is not directly supported because it mentions a different medication (diethylcarbamazine) in combination with albendazole, and it does not explicitly state that albendazole alone prevents filariasis."
+13732336,Albendazole prevents helminthiasis,1026,"Our evaluation suggests that although additional studies are needed to determine optimal treatment regimens for intestinal parasites, especially among young children and pregnant women, a five-day course of pre-departure albendazole was effective in reducing helminthic infection in treated refugees.",True,"Is the triple 'Albendazole prevents helminthiasis' supported by the sentence: 'Our evaluation suggests that although additional studies are needed to determine optimal treatment regimens for intestinal parasites, especially among young children and pregnant women, a five-day course of pre-departure albendazole was effective in reducing helminthic infection in treated refugees.'?","Yes, the statement is indirectly supported because it indicates albendazole's effectiveness in reducing intestinal parasites, which includes certain types of helminthic infections, but it doesn't specifically mention prevention."
+25678577,Latamoxef treats bacterial infectious disease,1027,"Clinical efficacy and safety of a new oxacephem, moxalactam, in serious bacterial infections.",True,"Is the triple 'Latamoxef treats bacterial infectious disease' supported by the sentence: 'Clinical efficacy and safety of a new oxacephem, moxalactam, in serious bacterial infections.'?","Yes, it is indirectly supported. The given sentence suggests that moxalactam, another oxacephem like latamoxef, is clinically effective and safe in treating serious bacterial infections, implying that latamoxef could also have similar properties."
+15316470,Ibuprofen subclass of 2-Hydroxyibuprofen,1028,"The purpose of this study was the development and validation of an LC-MS-MS method for simultaneous analysis of ibuprofen (IBP), 2-hydroxyibuprofen (2-OH-IBP) enantiomers, and carboxyibuprofen (COOH-IBP) stereoisomers in fungi culture medium, to investigate the ability of some endophytic fungi to biotransform the chiral drug IBP into its metabolites.",False,"Is the triple 'Ibuprofen subclass of 2-Hydroxyibuprofen' supported by the sentence: 'The purpose of this study was the development and validation of an LC-MS-MS method for simultaneous analysis of ibuprofen (IBP), 2-hydroxyibuprofen (2-OH-IBP) enantiomers, and carboxyibuprofen (COOH-IBP) stereoisomers in fungi culture medium, to investigate the ability of some endophytic fungi to biotransform the chiral drug IBP into its metabolites.'?","No, the sentence does not directly support that Ibuprofen is a subclass of 2-Hydroxyibuprofen. Instead, it suggests that some endophytic fungi can biotransform Ibuprofen (IBP) into its metabolites, including 2-hydroxyibuprofen (2-OH-IBP) enantiomers, in fungi culture medium."
+16265626,Ibuprofen related to Arthralgia,1029,"AIMS: To carry out a randomized clinical trial to compare the effect of palmitoylethanolamide (PEA) versus ibuprofen, a nonsteroidal anti-inflammatory drug (NSAID), for pain relief in temporomandibular joint (TMJ) osteoarthritis or arthralgia.",True,"Is the triple 'Ibuprofen related to Arthralgia' supported by the sentence: 'AIMS: To carry out a randomized clinical trial to compare the effect of palmitoylethanolamide (PEA) versus ibuprofen, a nonsteroidal anti-inflammatory drug (NSAID), for pain relief in temporomandibular joint (TMJ) osteoarthritis or arthralgia.'?","Yes, the statement suggests that Ibuprofen is related to arthralgia (joint pain) in the context of a clinical trial comparing its effect on pain relief with palmitoylethanolamide (PEA) in temporomandibular joint (TMJ) osteoarthritis or arthralgia. This implies that Ibuprofen is being used as a treatment for arthralgia, thus it is indirectly related."
+14582794,Ibuprofen related to Pain,1030,"We investigated the analgesic efficacy of single doses of ibuprofen, tramadol and pregabalin in menthol-evoked cold pain in a randomized, placebo-controlled four-way cross-over study in 20 healthy volunteers.",True,"Is the triple 'Ibuprofen related to Pain' supported by the sentence: 'We investigated the analgesic efficacy of single doses of ibuprofen, tramadol and pregabalin in menthol-evoked cold pain in a randomized, placebo-controlled four-way cross-over study in 20 healthy volunteers.'?","Yes, the statement is indirectly supportive of the triple claim, as it mentions ibuprofen being studied for its analgesic (pain-relieving) efficacy, but it does not explicitly state that ibuprofen is related to pain in a direct cause-and-effect manner."
+11440746,Ibuprofen related to Toothache,1031,Double blind study on emorfazone and ibuprofen in dental pain and inflammation.,False,Is the triple 'Ibuprofen related to Toothache' supported by the sentence: 'Double blind study on emorfazone and ibuprofen in dental pain and inflammation.'?,"No, the statement does not directly support that Ibuprofen is related to toothache. It mentions a double-blind study about emorfazone and ibuprofen in dental pain and inflammation, but it does not explicitly state that Ibuprofen is related to toothache."
+9106384,Ibuprofen related to osteoarthritis,1032,Glucosamine sulfate compared to ibuprofen in osteoarthritis of the knee.,False,Is the triple 'Ibuprofen related to osteoarthritis' supported by the sentence: 'Glucosamine sulfate compared to ibuprofen in osteoarthritis of the knee.'?,"No, the sentence does not support a direct or indirect relationship between Ibuprofen and osteoarthritis. It compares Glucosamine Sulfate to Ibuprofen in the context of treating knee osteoarthritis, but it does not provide information about Ibuprofen's relation to osteoarthritis."
+8106985,Ibuprofen related to burn,1033,INTRODUCTION: The anti-inflammatory and anticoagulant effects of ibuprofen and heparin may enhance skin perfusion in cutaneous scald burns.,True,Is the triple 'Ibuprofen related to burn' supported by the sentence: 'INTRODUCTION: The anti-inflammatory and anticoagulant effects of ibuprofen and heparin may enhance skin perfusion in cutaneous scald burns.'?,"Yes, it is indirectly supported. Ibuprofen's anti-inflammatory effects could potentially help reduce inflammation in cutaneous scald burns, thereby possibly improving overall skin perfusion. However, it doesn't necessarily mean that ibuprofen is directly related to treating burns, but rather it might have a beneficial effect in the context of burn care due to its known pharmacological properties."
+13726345,Ibuprofen causes patent ductus arteriosus,1034,"CONCLUSIONS: Ibuprofen-induced patent ductus arteriosus closure improved pulmonary mechanics, decreased total lung water, increased epithelial sodium channel expression, and decreased the detrimental effects of preterm birth on alveolarization.",False,"Is the triple 'Ibuprofen causes patent ductus arteriosus' supported by the sentence: 'CONCLUSIONS: Ibuprofen-induced patent ductus arteriosus closure improved pulmonary mechanics, decreased total lung water, increased epithelial sodium channel expression, and decreased the detrimental effects of preterm birth on alveolarization.'?","No, this statement does not support a direct causal relationship between ibuprofen use and the development of patent ductus arteriosus (PDA). In fact, it suggests that ibuprofen may help in closing an existing PDA, improving lung function, reducing lung water, increasing epithelial sodium channel expression, and mitigating negative effects of preterm birth on alveolarization. However, it does not provide evidence for ibuprofen causing PDA."
+13653982,Ibuprofen causes Alzheimer disease,1035,Protein profile in neuroblastoma cells incubated with S- and R-enantiomers of ibuprofen by iTRAQ-coupled 2-D LC-MS/MS analysis: possible action of induced proteins on Alzheimer's disease.,False,Is the triple 'Ibuprofen causes Alzheimer disease' supported by the sentence: 'Protein profile in neuroblastoma cells incubated with S- and R-enantiomers of ibuprofen by iTRAQ-coupled 2-D LC-MS/MS analysis: possible action of induced proteins on Alzheimer's disease.'?,"No, this statement does not provide direct evidence that ibuprofen causes Alzheimer's disease. It suggests a possible connection through the investigation of proteins that may be influenced by ibuprofen, but it does not establish a causative relationship between ibuprofen and Alzheimer's disease."
+13133316,Ibuprofen causes peptic ulcer disease,1036,Protective effect of glucosamine against ibuprofen-induced peptic ulcer in rats.,False,Is the triple 'Ibuprofen causes peptic ulcer disease' supported by the sentence: 'Protective effect of glucosamine against ibuprofen-induced peptic ulcer in rats.'?,"No, it is not directly supported because it does not mention that ibuprofen causes peptic ulcer disease in humans, but it does suggest an indirect relationship, as it shows that glucosamine can protect against ibuprofen-induced peptic ulcers in rats, implying that ibuprofen may have a role in causing these ulcers."
+12641386,Ibuprofen causes Fever,1037,Ibuprofen-induced fever in Sjogren's syndrome.,False,Is the triple 'Ibuprofen causes Fever' supported by the sentence: 'Ibuprofen-induced fever in Sjogren's syndrome.'?,"No, it is not directly supported because the statement 'Ibuprofen-induced fever in Sjogren's syndrome' suggests that ibuprofen can cause a fever under certain conditions (in Sjogren's syndrome), not that ibuprofen generally causes a fever."
+12482174,Ibuprofen causes pancreatitis,1038,There have been no prior definite cases reported of ibuprofen-induced pancreatitis.,False,Is the triple 'Ibuprofen causes pancreatitis' supported by the sentence: 'There have been no prior definite cases reported of ibuprofen-induced pancreatitis.'?,"No, the statement does not support a direct link between Ibuprofen and pancreatitis, but rather suggests an absence of proven, definitive cases, which could be interpreted as indirect evidence against such a link. However, it does not confirm that Ibuprofen does not cause pancreatitis in any circumstances, as further research might reveal isolated incidents not yet documented."
+12438812,Ibuprofen causes Toothache,1039,"RESULTS: None of the studies established any of the COX-2 inhibitors as clearly better than ibuprofen, the current gold standard for the treatment of surgically induced dental pain.",False,"Is the triple 'Ibuprofen causes Toothache' supported by the sentence: 'RESULTS: None of the studies established any of the COX-2 inhibitors as clearly better than ibuprofen, the current gold standard for the treatment of surgically induced dental pain.'?","No, this statement does not support a direct link between Ibuprofen and toothache, nor does it provide evidence for Ibuprofen causing toothache (indirectly). The provided statement focuses on a comparison between different treatments for surgically induced dental pain, with Ibuprofen being used as a reference point, rather than discussing side effects or complications related to Ibuprofen use."
+12079834,Ibuprofen causes adult acute respiratory distress syndrome,1040,Noncardiogenic pulmonary edema due to ibuprofen.,True,Is the triple 'Ibuprofen causes adult acute respiratory distress syndrome' supported by the sentence: 'Noncardiogenic pulmonary edema due to ibuprofen.'?,"Yes, it is indirectly supported. The statement ""Noncardiogenic pulmonary edema due to ibuprofen"" suggests that ibuprofen can cause pulmonary edema, which is a symptom of adult acute respiratory distress syndrome (ARDS). Therefore, there is a potential link between ibuprofen use and ARDS, but it is not explicitly stated in this sentence."
+11157616,Ibuprofen causes Pain,1041,"In a double-blind cross-over study on 22 healthy subjects the analgesic efficacies of the antipyretic analgesic drugs ibuprofen, dipyrone and paracetamol were tested against placebo using a model of experimentally induced pain.",False,"Is the triple 'Ibuprofen causes Pain' supported by the sentence: 'In a double-blind cross-over study on 22 healthy subjects the analgesic efficacies of the antipyretic analgesic drugs ibuprofen, dipyrone and paracetamol were tested against placebo using a model of experimentally induced pain.'?","No, this statement does not directly support the triple 'Ibuprofen causes pain'. Instead, it describes a study where ibuprofen was tested for its analgesic (pain-relieving) efficacy in comparison to placebo and other drugs, suggesting that ibuprofen may actually alleviate pain."
+10429873,Ibuprofen causes Hemorrhage,1042,Unaltered ibuprofen-induced faecal blood loss upon coadministration of moclobemide.,False,Is the triple 'Ibuprofen causes Hemorrhage' supported by the sentence: 'Unaltered ibuprofen-induced faecal blood loss upon coadministration of moclobemide.'?,"No, it is not directly supported because the statement does not mention hemorrhage, but rather faecal blood loss. Indirectly, it might suggest that ibuprofen can cause some form of gastrointestinal bleeding, but it does not establish a direct link to hemorrhage."
+9800201,Ibuprofen causes arthritic joint disease,1043,The C5a antagonist (1 or 3 mg/kg/day) and/or ibuprofen (30 mg/kg/day) were administered orally on a daily basis either before or after arthritis induction.,False,Is the triple 'Ibuprofen causes arthritic joint disease' supported by the sentence: 'The C5a antagonist (1 or 3 mg/kg/day) and/or ibuprofen (30 mg/kg/day) were administered orally on a daily basis either before or after arthritis induction.'?,"No, this statement does not provide direct or indirect evidence to support the claim that Ibuprofen causes arthritic joint disease. Instead, it discusses the administration of Ibuprofen and a C5a antagonist, either before or after arthritis induction, which could be part of a study aimed at investigating potential treatments for arthritis rather than causing it."
+8163776,Ibuprofen causes injury,1044,RESULTS: Ketoprofen 50 mg t.d.s. suppressed prostaglandin synthesis to a significantly greater extent than ibuprofen and caused significantly more gastroduodenal injury.,True,Is the triple 'Ibuprofen causes injury' supported by the sentence: 'RESULTS: Ketoprofen 50 mg t.d.s. suppressed prostaglandin synthesis to a significantly greater extent than ibuprofen and caused significantly more gastroduodenal injury.'?,"Yes, the statement does provide indirect support for the idea that ibuprofen can cause gastroduodenal injury. The statement says that ketoprofen caused significantly more gastroduodenal injury than ibuprofen, which implies that ibuprofen did cause some level of gastroduodenal injury, even if it was less than that of ketoprofen."
+26701175,Ibuprofen affects rheumatoid arthritis,1045,The duration of action of sustained-release ibuprofen ('Brufen Retard') was investigated in a 14-day double-blind study involving 14 osteoarthritis and 10 rheumatoid arthritis patients.,False,Is the triple 'Ibuprofen affects rheumatoid arthritis' supported by the sentence: 'The duration of action of sustained-release ibuprofen ('Brufen Retard') was investigated in a 14-day double-blind study involving 14 osteoarthritis and 10 rheumatoid arthritis patients.'?,"No, this statement does not directly support that Ibuprofen affects rheumatoid arthritis, but it does provide evidence that Ibuprofen (specifically Brufen Retard) has been studied in relation to rheumatoid arthritis, implying some effect, whether positive, negative, or neutral, is associated with its use in this population."
+24384432,Ibuprofen affects migraine disorder,1046,This study attempts to investigate the effect of ibuprofen on reducing eye pain and migraine headaches caused by trochleitis.,True,Is the triple 'Ibuprofen affects migraine disorder' supported by the sentence: 'This study attempts to investigate the effect of ibuprofen on reducing eye pain and migraine headaches caused by trochleitis.'?,"Yes, it is indirectly supported. The sentence mentions that Ibuprofen has an effect on reducing eye pain and migraine headaches caused by trochleitis, which implies that it could affect migraine disorder in general, although it doesn't explicitly state it."
+23500890,Ibuprofen affects adult acute respiratory distress syndrome,1047,"Ibuprofen suppresses the production of various pro-inflammatory cytokines that are implicated in the ""cytokine storm"" and subsequent ARDS in COVID-19 disease.",True,"Is the triple 'Ibuprofen affects adult acute respiratory distress syndrome' supported by the sentence: 'Ibuprofen suppresses the production of various pro-inflammatory cytokines that are implicated in the ""cytokine storm"" and subsequent ARDS in COVID-19 disease.'?","Yes, it is indirectly supported. The statement explains that Ibuprofen can suppress the production of pro-inflammatory cytokines, which are implicated in the cytokine storm that can lead to ARDS in COVID-19 disease. This suggests that Ibuprofen could potentially have a protective effect against ARDS, including adult acute respiratory distress syndrome (ARDS). However, this is an indirect inference, as the original statement does not explicitly mention ARDS in adults."
+21214366,Ibuprofen affects bronchopulmonary dysplasia,1048,"After adjusting for covariates, the risk of BPD was associated independently with ibuprofen exposure (odds ratios (OR) 2.296, 95% confidence interval (CI): 1.166-4.522, p = 0.016).",True,"Is the triple 'Ibuprofen affects bronchopulmonary dysplasia' supported by the sentence: 'After adjusting for covariates, the risk of BPD was associated independently with ibuprofen exposure (odds ratios (OR) 2.296, 95% confidence interval (CI): 1.166-4.522, p = 0.016).'?","Yes, the triple ""Ibuprofen affects bronchopulmonary dysplasia"" is directly supported by the sentence. The sentence indicates that there is an independent association between ibuprofen exposure and the risk of bronchopulmonary dysplasia (BPD), with odds ratios (OR) of 2.296, 95% confidence interval (CI): 1.166-4.522, p = 0.016, which suggests that ibuprofen may have an effect on BPD."
+20886939,Ibuprofen affects Cognitive impairment,1049,The opposite effect of ibuprofen on ethanol-induced cognitive impairment as measured by two lateralized functions is consistent with the reports in tissue and animal models that central nervous system effects of ethanol may be mediated at least in part by prostaglandins.,True,Is the triple 'Ibuprofen affects Cognitive impairment' supported by the sentence: 'The opposite effect of ibuprofen on ethanol-induced cognitive impairment as measured by two lateralized functions is consistent with the reports in tissue and animal models that central nervous system effects of ethanol may be mediated at least in part by prostaglandins.'?,"Yes, it is indirectly supported. The sentence suggests that ibuprofen may affect cognitive impairment caused by ethanol through its action on prostaglandins, which are involved in the central nervous system effects of ethanol."
+12685801,Description treats Acute suppurative arthritis due to bacteria,2,"This is the first report of septic arthritis in humans caused by this microorganism, and the first description of B. vesicularis infection in an immunocompetent child.",False,"Is the triple 'Description treats Acute suppurative arthritis due to bacteria' supported by the sentence: 'This is the first report of septic arthritis in humans caused by this microorganism, and the first description of B. vesicularis infection in an immunocompetent child.'?","No, it's not directly supported because the sentence does not provide a detailed description of the symptoms or treatment of acute suppurative arthritis caused by B. vesicularis. However, it's indirectly supported as it mentions the first description of B. vesicularis infection in an immunocompetent child, which could imply a case of acute suppurative arthritis since it's a possible symptom of such infection."
+27481671,Provider treats Chronic pain,3,"Health providers continue to search for ways to explain, predict, and cure the misery caused by chronic pain.",True,"Is the triple 'Provider treats Chronic pain' supported by the sentence: 'Health providers continue to search for ways to explain, predict, and cure the misery caused by chronic pain.'?","Yes, it is indirectly supported because if health providers are searching for ways to explain, predict, and cure chronic pain, it implies that they recognize chronic pain as a condition that needs treatment (a provider 'treats' chronic pain), but it does not explicitly state that this treatment is effective (thus 'indirect' support)."
+19423160,Provider treats Sepsis,4,The objective of this review is to determine the effectiveness of provider strategies for the early recognition of clinical deterioration due to sepsis in pediatric patients.,True,Is the triple 'Provider treats Sepsis' supported by the sentence: 'The objective of this review is to determine the effectiveness of provider strategies for the early recognition of clinical deterioration due to sepsis in pediatric patients.'?,"Yes, it can be interpreted as indirectly supported, as recognizing clinical deterioration due to sepsis earlier could potentially lead to more effective treatment, thus implying that the provider strategy can treat sepsis effectively, but it's not a direct statement about treating sepsis itself."
+18994076,Provider treats transient ischemic attack,5,CONCLUSIONS: Primary and emergency care providers need to review how they can best handle patients presenting with symptoms that could be due to stroke or TIA.,True,Is the triple 'Provider treats transient ischemic attack' supported by the sentence: 'CONCLUSIONS: Primary and emergency care providers need to review how they can best handle patients presenting with symptoms that could be due to stroke or TIA.'?,"Yes, it is indirectly supported. The conclusion suggests that primary and emergency care providers should review their handling of patients with symptoms that could be due to stroke or TIA, implying that they should be prepared to provide appropriate treatment for these conditions, which includes transient ischemic attack (TIA)."
+18980233,Provider treats obesity disorder,6,"Progress notes were examined to extract need for weight management (WM), patient-provider discussions about risk due to overweight/obesity, recommended lifestyle changes and/or follow-up and WM education.",True,"Is the triple 'Provider treats obesity disorder' supported by the sentence: 'Progress notes were examined to extract need for weight management (WM), patient-provider discussions about risk due to overweight/obesity, recommended lifestyle changes and/or follow-up and WM education.'?","Yes, it is indirectly supported, as identifying a need for weight management, discussing risks due to overweight/obesity, recommending lifestyle changes, providing education, and arranging follow-ups can contribute to treating obesity as a disorder, but it does not explicitly state that the provider treats obesity as a disorder in this specific text snippet."
+17192662,Provider treats osteoarthritis,7,"CONCLUSION: Training rural providers to perform knee injections for patients with knee pain secondary to osteoarthritis appears cost effective using the commonly used threshold of $50,000/QALY if more than 20 such patients per year are seen at rural primary care clinics.",True,"Is the triple 'Provider treats osteoarthritis' supported by the sentence: 'CONCLUSION: Training rural providers to perform knee injections for patients with knee pain secondary to osteoarthritis appears cost effective using the commonly used threshold of $50,000/QALY if more than 20 such patients per year are seen at rural primary care clinics.'?","Yes, it is indirectly supported because it suggests that training primary care clinicians to provide a specific treatment for patients with knee pain due to osteoarthritis is cost-effective, implying that this treatment can be beneficial for these patients, which aligns with the statement that a provider treats osteoarthritis. However, it does not explicitly state that this is a direct treatment for osteoarthritis itself, but rather a treatment for symptoms caused by osteoarthritis, specifically knee pain."
+16604884,Provider treats cerebral palsy,8,"This article describes the results of surveys completed by disability service providers and individuals with CCN due to cerebral palsy, developmental delay, and acquired disabilities.",Undefined,"Is the triple 'Provider treats cerebral palsy' supported by the sentence: 'This article describes the results of surveys completed by disability service providers and individuals with CCN due to cerebral palsy, developmental delay, and acquired disabilities.'?","Indirectly, as the mentioned survey responses from disability service providers may include information about their treatment for individuals with cerebral palsy, but it is not explicitly stated in this sentence that they treat cerebral palsy specifically, nor is it stated that they use a specific method, like Providers treating cerebral palsy, to do so."
+15941387,Provider treats Rotavirus infection,9,"We estimated health provider costs, economic costs and quality-adjusted life years (QALYs) lost due to rotavirus infections.",True,"Is the triple 'Provider treats Rotavirus infection' supported by the sentence: 'We estimated health provider costs, economic costs and quality-adjusted life years (QALYs) lost due to rotavirus infections.'?","Yes, it is indirectly supported because estimating health provider costs for rotavirus infections implies that there is a treatment for it, hence a provider treats rotavirus infections. However, it does not explicitly state that a specific treatment is effective against rotavirus infections."
+14457077,Provider treats Fatigue,10,"It seems reasonable to alternate chest compression providers every 2 min, to prevent the loss of effective compressions due to fatigue and to minimise interruptions of chest compressions.",True,"Is the triple 'Provider treats Fatigue' supported by the sentence: 'It seems reasonable to alternate chest compression providers every 2 min, to prevent the loss of effective compressions due to fatigue and to minimise interruptions of chest compressions.'?","Yes, it is indirectly supported. The sentence suggests that alternating chest compression providers can help prevent fatigue-related losses of effective compressions, implying that fatigue is a factor that affects a provider's ability to deliver effective compressions. Therefore, a provider treating fatigue would be in line with this statement."
+13583178,Provider treats stroke disorder,11,"Thus, families must increasingly partner with health service providers to promote their child's health and prevent the development of secondary conditions that may contribute to heart disease, stroke, respiratory diseases, low endurance and emotional difficulties.",True,"Is the triple 'Provider treats stroke disorder' supported by the sentence: 'Thus, families must increasingly partner with health service providers to promote their child's health and prevent the development of secondary conditions that may contribute to heart disease, stroke, respiratory diseases, low endurance and emotional difficulties.'?","Yes, it is indirectly supported. The sentence suggests that partnership between families and health service providers can help prevent conditions that may contribute to heart disease and stroke in children, implying that healthcare providers play a role in addressing these issues. However, it does not explicitly state that healthcare providers treat stroke disorders."
+13583177,Provider treats respiratory system disorder,12,"Thus, families must increasingly partner with health service providers to promote their child's health and prevent the development of secondary conditions that may contribute to heart disease, stroke, respiratory diseases, low endurance and emotional difficulties.",True,"Is the triple 'Provider treats respiratory system disorder' supported by the sentence: 'Thus, families must increasingly partner with health service providers to promote their child's health and prevent the development of secondary conditions that may contribute to heart disease, stroke, respiratory diseases, low endurance and emotional difficulties.'?","Yes, it is indirectly supported. The sentence mentions that families should work with healthcare providers to prevent conditions like respiratory diseases, which implies that healthcare providers can indeed treat such disorders. However, it doesn't explicitly state that a specific provider specializes in treating respiratory disorders."
+13583176,Provider treats heart disorder,13,"Thus, families must increasingly partner with health service providers to promote their child's health and prevent the development of secondary conditions that may contribute to heart disease, stroke, respiratory diseases, low endurance and emotional difficulties.",False,"Is the triple 'Provider treats heart disorder' supported by the sentence: 'Thus, families must increasingly partner with health service providers to promote their child's health and prevent the development of secondary conditions that may contribute to heart disease, stroke, respiratory diseases, low endurance and emotional difficulties.'?","No, it is not directly supported as it does not specifically mention that the provider treats a heart disorder. However it can be inferred as it talks about preventing secondary conditions that may contribute to heart disease which can be seen as an indirect support for the statement that a provider can treat a heart disorder."
+13436217,Provider treats asthma,14,"CAEs often advised callers (> 75%) to return to their asthma provider for assistance as a result of uncontrolled asthma, medication concerns, a questionable diagnosis, or the need for an action plan.",True,"Is the triple 'Provider treats asthma' supported by the sentence: 'CAEs often advised callers (> 75%) to return to their asthma provider for assistance as a result of uncontrolled asthma, medication concerns, a questionable diagnosis, or the need for an action plan.'?","Yes, it is indirectly supported because it suggests that providers play a role in managing asthma, but it does not explicitly state that they treat it."
+13417890,Provider treats Pain,15,"Reasons include: inflexibility by dialysis providers because of reduced profitability, claims that patients oppose the subcutaneous route because of pain at the site of injection, concerns regarding pure red cell aplasia associated with subcutaneous administration, and greater hemoglobin cycling with the subcutaneous route.",True,"Is the triple 'Provider treats Pain' supported by the sentence: 'Reasons include: inflexibility by dialysis providers because of reduced profitability, claims that patients oppose the subcutaneous route because of pain at the site of injection, concerns regarding pure red cell aplasia associated with subcutaneous administration, and greater hemoglobin cycling with the subcutaneous route.'?","Yes, it is indirectly supported. The statement mentions that patients oppose subcutaneous injection due to pain at the site (which supports 'treats pain') but it is not specifically about a 'provider' but about 'patients'. Also, it mentions concerns about subcutaneous administration in general which could be interpreted as a concern from 'providers'."
+26452787,Fenbendazole treats infectious disease,16,Fenbendazole was effective against induced infections of A tubaeforme and Taen taeniaeformis.,True,Is the triple 'Fenbendazole treats infectious disease' supported by the sentence: 'Fenbendazole was effective against induced infections of A tubaeforme and Taen taeniaeformis.'?,"Yes, it is indirectly supported. The given sentence suggests that Fenbendazole is effective against certain types of infections (A tubaeforme and Taen taeniaeformis), which aligns with the statement that Fenbendazole treats infectious diseases, although it does not explicitly mention all infectious diseases."
+26452786,Fenbendazole treats helminthiasis,17,Evaluation of granulated fenbendazole (22.2%) against induced and naturally occurring helminth infections in cats.,True,Is the triple 'Fenbendazole treats helminthiasis' supported by the sentence: 'Evaluation of granulated fenbendazole (22.2%) against induced and naturally occurring helminth infections in cats.'?,"Yes, it is indirectly supported. The title suggests that Fenbendazole, a drug, is being evaluated for its effectiveness against helminth infections in cats, which aligns with the statement that Fenbendazole treats helminthiasis (a condition characterized by infestation with parasitic worms)."
+25044562,Fenbendazole treats Intestinal nematode infection,18,"Efficacy of dichlorvos, fenbendazole, and ivermectin in swine with induced intestinal nematode infections.",True,"Is the triple 'Fenbendazole treats Intestinal nematode infection' supported by the sentence: 'Efficacy of dichlorvos, fenbendazole, and ivermectin in swine with induced intestinal nematode infections.'?","Yes, the statement is indirectly supported by the given sentence as it mentions Fenbendazole in relation to treating intestinal nematode infections in swine, which implies its efficacy in such infections."
+24521403,Fenbendazole treats Increased reactive oxygen species production,19,"Furthermore, we explored the associated mechanism, and our results showed that analog 6 and fenbendazole could induce oxidative stress by accumulating ROS.",True,"Is the triple 'Fenbendazole treats Increased reactive oxygen species production' supported by the sentence: 'Furthermore, we explored the associated mechanism, and our results showed that analog 6 and fenbendazole could induce oxidative stress by accumulating ROS.'?","Yes, it is indirectly supported because Fenbendazole is shown to induce oxidative stress by accumulating ROS, which could potentially lead to an increase in reactive oxygen species (ROS) production."
+23706249,Fenbendazole treats Adverse reactions,20,"However, it is known that administration of high, off-label doses of fenbendazole can lead to adverse reactions.",True,"Is the triple 'Fenbendazole treats Adverse reactions' supported by the sentence: 'However, it is known that administration of high, off-label doses of fenbendazole can lead to adverse reactions.'?","Yes, the statement about adverse reactions due to high doses does support the idea that fenbendazole can treat adverse reactions, but indirectly. It implies that managing dosage can help mitigate these adverse reactions, which could be interpreted as a form of treatment. However, it does not explicitly state that fenbendazole is used to treat adverse reactions in a direct cause-effect manner."
+19012088,Fenbendazole treats Immune response,21,Effect of fenbendazole and pyrantel tartrate on the induction of protective immunity in pigs naturally or experimentally infected with Ascaris suum.,False,Is the triple 'Fenbendazole treats Immune response' supported by the sentence: 'Effect of fenbendazole and pyrantel tartrate on the induction of protective immunity in pigs naturally or experimentally infected with Ascaris suum.'?,"No, it is not directly or indirectly supported by that sentence. The given sentence discusses the effect of Fenbendazole and Pyrantel Tartrate on protective immunity in pigs infected with Ascaris suum, but it does not mention anything about Fenbendazole's direct effect on immune response."
+16366394,Fenbendazole treats Apoptosis,22,"This is the first report to demonstrate the inhibition of proteasome function and induction of endoplasmic reticulum stress/reactive oxygen species-dependent apoptosis in human lung cancer cell lines by fenbendazole, which may represent a new class of anticancer agents showing selective toxicity against cancer cells.",True,"Is the triple 'Fenbendazole treats Apoptosis' supported by the sentence: 'This is the first report to demonstrate the inhibition of proteasome function and induction of endoplasmic reticulum stress/reactive oxygen species-dependent apoptosis in human lung cancer cell lines by fenbendazole, which may represent a new class of anticancer agents showing selective toxicity against cancer cells.'?","Yes, the statement ""Fenbendazole treats apoptosis in human lung cancer cell lines, representing a new class of anticancer agents with selective toxicity against cancer cells, due to its ability to inhibit proteasome function and induce endoplasmic reticulum stress/reactive oxygen species-dependent apoptosis"" can be inferred from the provided sentence, thus providing direct support for the triple claim in question."
+27756813,mebendazole treats granulomatous hepatitis,23,Granulomatous hepatitis due to mebendazole.,True,Is the triple 'mebendazole treats granulomatous hepatitis' supported by the sentence: 'Granulomatous hepatitis due to mebendazole.'?,"Yes, it is indirectly supported. The given statement ""Granulomatous hepatitis due to mebendazole."" implies that mebendazole can cause granulomatous hepatitis, which suggests that treating such a condition might involve using mebendazole, although this is not explicitly stated in the sentence."
+27730862,mebendazole treats Cytoplasmic Alteration,24,The cellular changes documented are likely to account for previously described cytoplasmic alterations induced by MBZ.,True,Is the triple 'mebendazole treats Cytoplasmic Alteration' supported by the sentence: 'The cellular changes documented are likely to account for previously described cytoplasmic alterations induced by MBZ.'?,"Yes, it is indirectly supported. The sentence suggests that mebendazole (MBZ) induces cytoplasmic alterations, which aligns with the statement ""mebendazole treats Cytoplasmic Alteration"". However, it doesn't explicitly state that MBZ is used to treat cytoplasmic alterations, hence it's an indirect support."
+26407395,mebendazole treats infectious disease,25,"A formulation of mebendazole was used to determine the optimal dosage level against induced and/or naturally occurring infections of Toxocara cati, Ancylostoma tubaeforme, and Taenia taeniaeformis in cats.",True,"Is the triple 'mebendazole treats infectious disease' supported by the sentence: 'A formulation of mebendazole was used to determine the optimal dosage level against induced and/or naturally occurring infections of Toxocara cati, Ancylostoma tubaeforme, and Taenia taeniaeformis in cats.'?","Yes, it is indirectly supported. The sentence mentions that a formulation of mebendazole was used to determine optimal dosage against certain infections in cats, which implies that mebendazole is used to treat those infections, thus supporting the idea that it is used for infectious diseases."
+26407394,mebendazole treats helminthiasis,26,Anthelmintic activity of mebendazole against induced and naturally occurring helminth infections in cats.,True,Is the triple 'mebendazole treats helminthiasis' supported by the sentence: 'Anthelmintic activity of mebendazole against induced and naturally occurring helminth infections in cats.'?,"Yes, it is indirectly supported because anthelmintic activity against induced and naturally occurring helminth infections in cats implies that mebendazole can treat infections caused by these parasitic worms, which is what helminthiasis refers to."
+26245282,mebendazole treats Sedentary,27,"The effects are not rapid, however, for only mebendazole at 500 micrograms/ml treats total inactivity of the fluke within a 12-hr period.",False,"Is the triple 'mebendazole treats Sedentary' supported by the sentence: 'The effects are not rapid, however, for only mebendazole at 500 micrograms/ml treats total inactivity of the fluke within a 12-hr period.'?","No, it is not directly supported because it mentions 'total inactivity of the fluke' instead of 'Sedentary'. Also, it does not explicitly state that 'mebendazole at 500 micrograms/ml treats' sedentary behavior in humans or animals, but rather inactivity in a specific organism under specific conditions."
+24434072,mebendazole treats Vascular System Injuries,28,Mebendazole-Induced Blood-Testis Barrier Injury in Mice Testes by Disrupting Microtubules in Addition to Triggering Programmed Cell Death.,False,Is the triple 'mebendazole treats Vascular System Injuries' supported by the sentence: 'Mebendazole-Induced Blood-Testis Barrier Injury in Mice Testes by Disrupting Microtubules in Addition to Triggering Programmed Cell Death.'?,"No, this statement does not directly support the claim that mebendazole treats vascular system injuries. The provided sentence discusses the effects of mebendazole on the blood-testis barrier in mice testes, but it does not mention any therapeutic effects on the vascular system."
+23551876,mebendazole treats Inflammation,29,"Using early models of pancreatic cancer, treatment with mebendazole resulted in less inflammation, decreased dysplasia, with the later stage model additionally showing a decreased tumor burden, less advanced tumors, and a reduction of metastasis.",True,"Is the triple 'mebendazole treats Inflammation' supported by the sentence: 'Using early models of pancreatic cancer, treatment with mebendazole resulted in less inflammation, decreased dysplasia, with the later stage model additionally showing a decreased tumor burden, less advanced tumors, and a reduction of metastasis.'?","Yes, it is indirectly supported because the information provided suggests that mebendazole can reduce inflammation in a model of pancreatic cancer, but it does not specifically mention inflammation caused by a particular condition like 'Inflammation'."
+23464334,mebendazole treats Cancer-Related Death,30,"CONCLUSION: Mebendazole and albendazole were shown to cause selective cancer cell death via a mechanism of classical apoptosis and cell cycle arrest, involving the destabilisation of microtubules.",True,"Is the triple 'mebendazole treats Cancer-Related Death' supported by the sentence: 'CONCLUSION: Mebendazole and albendazole were shown to cause selective cancer cell death via a mechanism of classical apoptosis and cell cycle arrest, involving the destabilisation of microtubules.'?","Yes, it is indirectly supported. The given conclusion suggests that mebendazole causes selective cancer cell death, which implies that it could potentially treat cancer, thus reducing cancer-related deaths. However, it does not directly state that mebendazole reduces cancer-related deaths."
+21460286,mebendazole treats Increased Apoptosis,31,"CONCLUSIONS: Docetaxel and mebendazole target distinct aspects of the microtubule dynamics, leading to increased apoptosis and reduced tumour growth.",True,"Is the triple 'mebendazole treats Increased Apoptosis' supported by the sentence: 'CONCLUSIONS: Docetaxel and mebendazole target distinct aspects of the microtubule dynamics, leading to increased apoptosis and reduced tumour growth.'?","Yes, the statement is indirectly supported, as it suggests that mebendazole, like docetaxel, can increase apoptosis, but it does not explicitly state that mebendazole treats increased apoptosis."
+21460285,mebendazole treats Growth delay,32,"CONCLUSIONS: Docetaxel and mebendazole target distinct aspects of the microtubule dynamics, leading to increased apoptosis and reduced tumour growth.",False,"Is the triple 'mebendazole treats Growth delay' supported by the sentence: 'CONCLUSIONS: Docetaxel and mebendazole target distinct aspects of the microtubule dynamics, leading to increased apoptosis and reduced tumour growth.'?","No, it is not directly supported because the statement does not mention growth delay specifically, but it can be interpreted as supporting it indirectly as it mentions reduced tumour growth, which could imply a slowing of growth processes, including growth delays in certain contexts."
+21233324,mebendazole treats hepatitis,33,"CASE SUMMARY: Differently from other cases of hepatitis due to MBZ reported in the scientific literature, our patient received standard doses of MBZ for a short period of time.",False,"Is the triple 'mebendazole treats hepatitis' supported by the sentence: 'CASE SUMMARY: Differently from other cases of hepatitis due to MBZ reported in the scientific literature, our patient received standard doses of MBZ for a short period of time.'?","No, this sentence does not provide direct or indirect support for the statement that mebendazole (MBZ) treats hepatitis. It discusses a case of hepatitis caused by MBZ, not how MBZ was used to treat hepatitis in this case."
+21233321,mebendazole treats Injury of liver,34,"Although MBZ has been reported to cause hepatic injury, case reports of severe hepatic injury are very rare.",False,"Is the triple 'mebendazole treats Injury of liver' supported by the sentence: 'Although MBZ has been reported to cause hepatic injury, case reports of severe hepatic injury are very rare.'?","No, it is not directly supported, as the sentence mentions that mebendazole (MBZ) can cause 'hepatic injury', but it also states that severe cases are very rare, implying that overall, mebendazole is relatively safe for the liver. Therefore, it does not support the claim that mebendazole 'treats' injury of the liver, rather it suggests it may potentially cause it in rare cases, making it more likely a side effect than a treatment option for liver injury."
+21233320,mebendazole treats Hepatotoxicity,35,Hepatotoxicity caused by mebendazole in a patient with Gilbert's syndrome.,False,Is the triple 'mebendazole treats Hepatotoxicity' supported by the sentence: 'Hepatotoxicity caused by mebendazole in a patient with Gilbert's syndrome.'?,"No, it is not directly supported because the given sentence mentions that hepatotoxicity was caused by mebendazole, but it does not state that mebendazole treats hepatotoxicity."
+20804454,mebendazole treats Autophagy,36,"Consequently, we suggest that MBZ induces autophagy in ECs and that protective autophagy can be a novel target for enhancing the anti-angiogenic efficacy of MBZ in cancer treatment.",True,"Is the triple 'mebendazole treats Autophagy' supported by the sentence: 'Consequently, we suggest that MBZ induces autophagy in ECs and that protective autophagy can be a novel target for enhancing the anti-angiogenic efficacy of MBZ in cancer treatment.'?","Yes, it is indirectly supported. The given sentence suggests that mebendazole (MBZ) can induce autophagy in endothelial cells (ECs) and this could potentially enhance its anti-angiogenic efficacy in cancer treatment. Therefore, while the sentence does not explicitly state that mebendazole treats autophagy, it does imply that mebendazole can influence autophagy, which is a form of treatment."
+20350721,mebendazole treats Poisoning by theophylline,37,It is concluded that at therapeutic doses it is unlikely that mebendazole or albendazole will induce theophylline toxicity if co-administered with the bronchodilator.,False,Is the triple 'mebendazole treats Poisoning by theophylline' supported by the sentence: 'It is concluded that at therapeutic doses it is unlikely that mebendazole or albendazole will induce theophylline toxicity if co-administered with the bronchodilator.'?,"No, it's not directly supported because the sentence does not mention poisoning, but it does suggest that mebendazole is unlikely to induce theophylline toxicity when co-administered, which could be interpreted as it not causing poisoning by theophylline."
+19850774,mebendazole treats Senility,38,"Cell cycle distribution and nuclear morphometric analysis indicated that the triple combination of TMZ, VBL and MBZ (TVM) was able to induce polyploidy and senescence, in addition to increasing the Notch3 RNA level in patient-derived gliomas.",False,"Is the triple 'mebendazole treats Senility' supported by the sentence: 'Cell cycle distribution and nuclear morphometric analysis indicated that the triple combination of TMZ, VBL and MBZ (TVM) was able to induce polyploidy and senescence, in addition to increasing the Notch3 RNA level in patient-derived gliomas.'?","No, it is not directly supported because the statement does not claim that mebendazole (MBZ) can treat senility, but rather it suggests a relationship with polyploidy, senescence, and Notch3 RNA level increase in patient-derived gliomas when used in a specific drug combination (TVM)."
+19850773,mebendazole treats polyploidy,39,"Cell cycle distribution and nuclear morphometric analysis indicated that the triple combination of TMZ, VBL and MBZ (TVM) was able to induce polyploidy and senescence, in addition to increasing the Notch3 RNA level in patient-derived gliomas.",False,"Is the triple 'mebendazole treats polyploidy' supported by the sentence: 'Cell cycle distribution and nuclear morphometric analysis indicated that the triple combination of TMZ, VBL and MBZ (TVM) was able to induce polyploidy and senescence, in addition to increasing the Notch3 RNA level in patient-derived gliomas.'?","No, it is not directly supported because mebendazole is not stated to treat polyploidy in this statement, but it is mentioned as part of a combination of drugs (TVM) that induces polyploidy in patient-derived gliomas."
+19593283,mebendazole treats Morphologically altered structure,40,"Mebendazole showed antifungal activity against phagocytized C. neoformans, affected cryptococcal biofilms profoundly and caused marked morphological alterations in C. neoformans, including reduction of capsular dimensions.",True,"Is the triple 'mebendazole treats Morphologically altered structure' supported by the sentence: 'Mebendazole showed antifungal activity against phagocytized C. neoformans, affected cryptococcal biofilms profoundly and caused marked morphological alterations in C. neoformans, including reduction of capsular dimensions.'?","Yes, the statement is indirectly supported by the given sentence. Mebendazole does cause marked morphological alterations in C. neoformans, as stated in the sentence, which aligns with the claim that it affects morphologically altered structures. However, it's important to note that this is an inference, not a direct statement in the provided sentence."
+19452008,mebendazole treats active peptic ulcer disease,41,"The patient underwent multiple blood transfusions before referral to the Aga Khan University Hospital (AKUH), Karachi and was managed conservatively with mebendazole at our hospital after exclusion of other possible treats of gastrointestinal bleeding.",False,"Is the triple 'mebendazole treats active peptic ulcer disease' supported by the sentence: 'The patient underwent multiple blood transfusions before referral to the Aga Khan University Hospital (AKUH), Karachi and was managed conservatively with mebendazole at our hospital after exclusion of other possible treats of gastrointestinal bleeding.'?","No, this statement does not support that mebendazole is an effective treatment for active peptic ulcer disease, nor is it an indirect support as it does not mention anything about treating peptic ulcers with mebendazole. The statement says that a patient was managed with mebendazole at their hospital, but it does not provide enough information to make a connection between mebendazole and treating an active peptic ulcer disease."
+18898185,mebendazole treats Fetal anomaly,42,"In this study, we performed in vivo imaging of the retinas of zebrafish larvae exposed to MBZ, and found that exposure to MBZ during 2 and 3 days post-fertilization caused malformation of the retinal layers.",True,"Is the triple 'mebendazole treats Fetal anomaly' supported by the sentence: 'In this study, we performed in vivo imaging of the retinas of zebrafish larvae exposed to MBZ, and found that exposure to MBZ during 2 and 3 days post-fertilization caused malformation of the retinal layers.'?","Yes, it is indirectly supported. The sentence mentions that exposure to mebendazole (MBZ) during certain developmental stages of zebrafish larvae causes malformation of the retinal layers. While it does not explicitly state that mebendazole treats fetal anomaly, it does suggest that exposure to mebendazole can result in developmental abnormalities, which could be interpreted as a form of treatment if used to correct existing anomalies. However, this is a significant extrapolation from the given sentence and would require further research to confirm."
+15210811,mebendazole treats injury,43,Oral helminthic mebendazole (MBZ) has been reported to cause liver injury with inflammatory responses.,False,Is the triple 'mebendazole treats injury' supported by the sentence: 'Oral helminthic mebendazole (MBZ) has been reported to cause liver injury with inflammatory responses.'?,"No, it is not directly supported because the sentence mentions that mebendazole can cause liver injury, not that it treats injuries in general."
+13885379,mebendazole treats Inactivation,44,Mebendazole induces apoptosis via Bcl-2 inactivation in chemoresistant melanoma cells.,True,Is the triple 'mebendazole treats Inactivation' supported by the sentence: 'Mebendazole induces apoptosis via Bcl-2 inactivation in chemoresistant melanoma cells.'?,"Yes, it is indirectly supported. The given sentence states that mebendazole induces apoptosis (cell death) in chemoresistant melanoma cells through the inactivation of Bcl-2, which is a protein that inhibits apoptosis. Therefore, mebendazole's effect on Bcl-2 inactivation does support the idea that it can inactivate, and thus treat, certain biological processes related to disease, in this case, in chemoresistant melanoma cells."
+12876761,mebendazole treats infertility disorder,45,"The evaluation also highlighted that there were critical issues for the successful implementation of the program such as the issue of educating illiterate mothers, higher involvement of families in the mass treatment process, ability to reach a larger number of school absentees, and overcoming the prejudice against externally funded measures, which are perceived by some of the members of the community as an experiment run by foreigners on the local population and the concern of some parents that anthelmintic drug (mebendazole) might cause sexual sterility.",False,"Is the triple 'mebendazole treats infertility disorder' supported by the sentence: 'The evaluation also highlighted that there were critical issues for the successful implementation of the program such as the issue of educating illiterate mothers, higher involvement of families in the mass treatment process, ability to reach a larger number of school absentees, and overcoming the prejudice against externally funded measures, which are perceived by some of the members of the community as an experiment run by foreigners on the local population and the concern of some parents that anthelmintic drug (mebendazole) might cause sexual sterility.'?","No, the statement ""mebendazole treats infertility disorder"" is not directly or indirectly supported by this sentence. The passage discusses challenges in implementing a program related to mebendazole, an anthelmintic drug used to treat parasitic worm infections, but it does not mention or imply any effect of mebendazole on fertility or infertility."
+11280026,mebendazole treats Increased reactive oxygen species production,46,"A comparative study of albendazole and mebendazole-induced, time-dependent oxidative stress.",False,"Is the triple 'mebendazole treats Increased reactive oxygen species production' supported by the sentence: 'A comparative study of albendazole and mebendazole-induced, time-dependent oxidative stress.'?","No, it is not directly supported because the given title talks about a comparison between oxidative stress induced by two drugs, but it does not mention anything about increased reactive oxygen species production being treated by mebendazole."
+11046187,mebendazole treats poisoning,47,"Longer incubation of the cells with MBZ resulted in stronger toxicity, and the cytotoxicity was dependent on the MBZ concentration above a certain threshold value (0.25-0.50 mg/l in a 42-h culture).",Undefined,"Is the triple 'mebendazole treats poisoning' supported by the sentence: 'Longer incubation of the cells with MBZ resulted in stronger toxicity, and the cytotoxicity was dependent on the MBZ concentration above a certain threshold value (0.25-0.50 mg/l in a 42-h culture).'?","The statement suggests that mebendazole (MBZ) has toxic effects on cells at certain concentrations, but it does not explicitly state that mebendazole is used to treat poisoning. Therefore, I would say that the statement does not directly support the claim that mebendazole treats poisoning, but it could indirectly support the idea that mebendazole has toxic effects, which could potentially be useful in treating certain types of poisoning under specific circumstances. However, this is an interpretation based on the information provided, and further research would be needed to confirm this hypothesis."
+11046186,mebendazole treats cytotoxicity,48,"Longer incubation of the cells with MBZ resulted in stronger toxicity, and the cytotoxicity was dependent on the MBZ concentration above a certain threshold value (0.25-0.50 mg/l in a 42-h culture).",True,"Is the triple 'mebendazole treats cytotoxicity' supported by the sentence: 'Longer incubation of the cells with MBZ resulted in stronger toxicity, and the cytotoxicity was dependent on the MBZ concentration above a certain threshold value (0.25-0.50 mg/l in a 42-h culture).'?","Yes, this statement does support that mebendazole (MBZ) has a concentration-dependent effect on cell toxicity, which can be interpreted as a form of indirect support for the statement that mebendazole can treat cytotoxicity, as higher concentrations appear to reduce cell viability in this context."
+9926628,mebendazole treats Secondary malignant neoplasm of lung,49,Oral administration of MZ in mice elicited a strong antitumor effect in a s.c. model and reduced lung colonies in experimentally induced lung metastasis without any toxicity when compared with paclitaxel-treated mice.,Undefined,Is the triple 'mebendazole treats Secondary malignant neoplasm of lung' supported by the sentence: 'Oral administration of MZ in mice elicited a strong antitumor effect in a s.c. model and reduced lung colonies in experimentally induced lung metastasis without any toxicity when compared with paclitaxel-treated mice.'?,"Indirectly, because it shows that mebendazole has antitumor effects in a mouse model, but it doesn't specifically mention Secondary malignant neoplasm of lung."
+9926626,mebendazole treats spindle assembly,50,"MZ induces abnormal spindle formation in mitotic cancer cells and enhances the depolymerization of tubulin, but the efficacy of depolymerization by MZ is lower than that by nocodazole.",True,"Is the triple 'mebendazole treats spindle assembly' supported by the sentence: 'MZ induces abnormal spindle formation in mitotic cancer cells and enhances the depolymerization of tubulin, but the efficacy of depolymerization by MZ is lower than that by nocodazole.'?","Yes, it is indirectly supported. The statement mentions that mebendazole (MZ) causes abnormal spindle formation and enhances tubulin depolymerization, which aligns with the concept of MZ treating spindle assembly issues. However, it doesn't explicitly state that MZ treats spindle assembly, hence it's an indirect support."
+9926624,mebendazole treats Apoptosis,51,The anthelmintic drug mebendazole induces mitotic arrest and apoptosis by depolymerizing tubulin in non-small cell lung cancer cells.,True,Is the triple 'mebendazole treats Apoptosis' supported by the sentence: 'The anthelmintic drug mebendazole induces mitotic arrest and apoptosis by depolymerizing tubulin in non-small cell lung cancer cells.'?,"Yes, this statement does support the claim that mebendazole can induce apoptosis, as mentioned in your proposed triple statement. The mechanism suggested in this statement is through depolymerizing tubulin in non-small cell lung cancer cells, which leads to mitotic arrest and eventually apoptosis. Therefore, it can be said that there is a direct connection, as the mechanism of action is provided in this statement."
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