index.html

---
layout: default
description: >-
  The Open Free Energy initiative is dedicated to the development of
  **open-source** tools for **binding free energy** calculations to guide
  pharmaceutical **drug design and discovery**.
bullets:
  - image: 
      src: assets/images/main/code-image.jpg
      alt: "Code from Open Free Energy, in a terminal"
    text: >-
      ## OPEN SOURCE

      Our software is [developed in public on
      GitHub](https://github.com/OpenFreeEnergy) and is released under the permissive
      MIT license.
  - image:
      src: assets/images/main/p381aa.png
      alt: "Ligand in the binding pocket of a protein"
    text: >-
      ## BINDING FREE ENERGY 

      We develop tools that enable our users to easily and efficiently
      calculate binding free energies for networks of molecular systems.
  - image:
      src: assets/images/main/drugDesign1_free.png
      alt: "Network of ligand transformations"
    text: >-
      ## DRUG DESIGN AND DISCOVERY

      Our tools are designed with pharmaceutical lead optimization in mind,
      and we work closely with our board members in industry to develop
      tools that meet the needs of real-world users.
bottom: >-
  ## Open Free Energy is hosted by the [Open Molecular Software
  Foundation](https://omsf.io).
---

<section class="hero">
  <div class="text-container">
    <h1>{{ page.title }}</h1>
    <p class="subtext">{{ page.description | markdownify }}</p>
    <div class="cta button alt">
        <a href="http://try.openfree.energy">Try It Online</a>
    </div>
    {% if page.hero %}
    <div>
      <img src="{{ page.hero.src }}" alt="{{ page.hero.alt }}" />
    </div>
    {% endif %}
  </div>
</section>

<div class="content">
  {% for bullet in page.bullets %}
  <section>
    <div class="container flex">
      <div class="text">
        {{ bullet.text | markdownify }}
      </div>
      <div class="image">
        <img class="main-page-bullet" src="{{ bullet.image.src }}" alt="{{ bullet.image.alt }}" />
      </div>
    </div>
  </section>
  {% endfor %}

  {% if page.bottom %}
  <section class="bottom-cta">
    {{ page.bottom | markdownify }}
  </section>
  {% endif %}