diff --git a/src/components/date-range/date-range-test.stories.tsx b/src/components/date-range/date-range-test.stories.tsx
index f0c2eb7577..f2176d88c2 100644
--- a/src/components/date-range/date-range-test.stories.tsx
+++ b/src/components/date-range/date-range-test.stories.tsx
@@ -64,6 +64,10 @@ DateRangeStory.args = {
   allowEmptyValueOnStartDate: undefined,
   allowEmptyValueOnEndDate: undefined,
   labelsInline: false,
+  datePickerStartAriaLabel: "start aria-label",
+  datePickerStartAriaLabelledBy: "start aria-labelledby",
+  datePickerEndAriaLabel: "end aria-label",
+  datePickerEndAriaLabelledBy: "end aria-labelledby",
 };
 
 export const DateRangeCustom = ({
diff --git a/src/components/date-range/date-range.component.tsx b/src/components/date-range/date-range.component.tsx
index ff1dde9a08..fa3bd5e2e4 100644
--- a/src/components/date-range/date-range.component.tsx
+++ b/src/components/date-range/date-range.component.tsx
@@ -118,6 +118,14 @@ export interface DateRangeProps
   isOptional?: boolean;
   /** Date format string to be applied to the date inputs */
   dateFormatOverride?: string;
+  /** Prop to specify the aria-label attribute of the start date picker */
+  datePickerStartAriaLabel?: string;
+  /** Prop to specify the aria-labelledby attribute of the start date picker */
+  datePickerStartAriaLabelledBy?: string;
+  /** Prop to specify the aria-label attribute of the end date picker */
+  datePickerEndAriaLabel?: string;
+  /** Prop to specify the aria-labelledby attribute of the end date picker */
+  datePickerEndAriaLabelledBy?: string;
 }
 
 export const DateRange = ({
@@ -135,6 +143,10 @@ export const DateRange = ({
   endRef,
   required,
   isOptional,
+  datePickerStartAriaLabel,
+  datePickerStartAriaLabelledBy,
+  datePickerEndAriaLabel,
+  datePickerEndAriaLabelledBy,
   ...rest
 }: DateRangeProps) => {
   const { validationRedesignOptIn } = useContext(NewValidationContext);
@@ -373,6 +385,8 @@ export const DateRange = ({
           labelWidth={inlineLabelWidth} // Textbox only applies this when labelsInLine prop is true
           tooltipPosition={tooltipPosition}
           ref={startRef}
+          datePickerAriaLabel={datePickerStartAriaLabel}
+          datePickerAriaLabelledBy={datePickerStartAriaLabelledBy}
         />
         <DateInput
           my={0} // prevents any form spacing being applied
@@ -383,6 +397,8 @@ export const DateRange = ({
           labelWidth={inlineLabelWidth} // Textbox only applies this when labelsInLine prop is true
           tooltipPosition={tooltipPosition}
           ref={endRef}
+          datePickerAriaLabel={datePickerEndAriaLabel}
+          datePickerAriaLabelledBy={datePickerEndAriaLabelledBy}
         />
       </DateRangeContext.Provider>
     </StyledDateRange>
diff --git a/src/components/date-range/date-range.test.tsx b/src/components/date-range/date-range.test.tsx
index b52d4a946a..98909b4d8f 100644
--- a/src/components/date-range/date-range.test.tsx
+++ b/src/components/date-range/date-range.test.tsx
@@ -679,6 +679,50 @@ test("should close the open 'start' picker when the user moves focus to the `end
   expect(within(startDate).queryByRole("grid")).not.toBeInTheDocument();
 });
 
+test("should apply aria-label and aria-labelledby to the date picker region", async () => {
+  const user = userEvent.setup();
+  render(
+    <DateRange
+      startLabel="start"
+      endLabel="end"
+      value={["10/10/2016", "11/11/2016"]}
+      onChange={() => {}}
+      startDateProps={{ disablePortal: true, "data-role": "start" }}
+      endDateProps={{ disablePortal: true, "data-role": "end" }}
+      datePickerStartAriaLabel="start aria-label"
+      datePickerStartAriaLabelledBy="start aria-labelledby"
+      datePickerEndAriaLabel="end aria-label"
+      datePickerEndAriaLabelledBy="end aria-labelledby"
+    />,
+  );
+  const startDate = screen.getByTestId("start");
+  const endDate = screen.getByTestId("end");
+
+  await user.click(screen.getByRole("textbox", { name: "start" }));
+
+  expect(within(startDate).getByRole("region")).toBeVisible();
+  expect(within(startDate).getByRole("region")).toHaveAttribute(
+    "aria-label",
+    "start aria-label",
+  );
+  expect(within(startDate).getByRole("region")).toHaveAttribute(
+    "aria-labelledby",
+    "start aria-labelledby",
+  );
+
+  await user.click(screen.getByRole("textbox", { name: "end" }));
+
+  expect(within(endDate).getByRole("region")).toBeVisible();
+  expect(within(endDate).getByRole("region")).toHaveAttribute(
+    "aria-label",
+    "end aria-label",
+  );
+  expect(within(endDate).getByRole("region")).toHaveAttribute(
+    "aria-labelledby",
+    "end aria-labelledby",
+  );
+});
+
 test("should close the open 'end' picker when the user moves focus to the `start` input", async () => {
   const user = userEvent.setup();
   render(
diff --git a/src/components/date/__internal__/date-picker/date-picker.component.tsx b/src/components/date/__internal__/date-picker/date-picker.component.tsx
index 14a7890b08..b76ee78993 100644
--- a/src/components/date/__internal__/date-picker/date-picker.component.tsx
+++ b/src/components/date/__internal__/date-picker/date-picker.component.tsx
@@ -63,6 +63,10 @@ export interface DatePickerProps {
   pickerTabGuardId?: string;
   /** Callback triggered when the picker is closed */
   onPickerClose?: () => void;
+  /** Prop to specify the aria-label attribute of the date picker */
+  ariaLabel?: string;
+  /** Prop to specify the aria-labelledby attribute of the date picker */
+  ariaLabelledBy?: string;
 }
 
 const popoverMiddleware = [
@@ -85,6 +89,8 @@ export const DatePicker = ({
   setOpen,
   pickerTabGuardId,
   onPickerClose,
+  ariaLabel: datePickerAriaLabel,
+  ariaLabelledBy: datePickerAriaLabelledBy,
 }: DatePickerProps) => {
   const [focusedMonth, setFocusedMonth] = useState<Date | undefined>(
     selectedDays || new Date(),
@@ -226,6 +232,9 @@ export const DatePicker = ({
           onMouseDown={pickerMouseDown}
           onKeyUp={handleKeyUp}
           onKeyDown={handleOnKeyDown}
+          role="region"
+          aria-label={datePickerAriaLabel}
+          aria-labelledby={datePickerAriaLabelledBy}
         >
           <div
             id={pickerTabGuardId}
diff --git a/src/components/date/date.component.tsx b/src/components/date/date.component.tsx
index 85d8755363..663861bb87 100644
--- a/src/components/date/date.component.tsx
+++ b/src/components/date/date.component.tsx
@@ -104,6 +104,10 @@ export interface DateInputProps
   onPickerClose?: () => void;
   /** Date format string to be applied to the date inputs */
   dateFormatOverride?: string;
+  /** Prop to specify the aria-label attribute of the date picker */
+  datePickerAriaLabel?: string;
+  /** Prop to specify the aria-labelledby attribute of the date picker */
+  datePickerAriaLabelledBy?: string;
 }
 
 export const DateInput = React.forwardRef<HTMLInputElement, DateInputProps>(
@@ -137,6 +141,8 @@ export const DateInput = React.forwardRef<HTMLInputElement, DateInputProps>(
       inputName,
       onPickerClose,
       onPickerOpen,
+      datePickerAriaLabel,
+      datePickerAriaLabelledBy,
       ...rest
     }: DateInputProps,
     ref,
@@ -541,6 +547,8 @@ export const DateInput = React.forwardRef<HTMLInputElement, DateInputProps>(
           setOpen={setOpen}
           pickerTabGuardId={pickerTabGuardId.current}
           onPickerClose={onPickerClose}
+          ariaLabel={datePickerAriaLabel}
+          ariaLabelledBy={datePickerAriaLabelledBy}
         />
       </StyledDateInput>
     );