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Error in downloading and unpacking unafold-3.8.tar.gz #6

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hafizmtalha opened this issue Dec 20, 2018 · 3 comments
Open

Error in downloading and unpacking unafold-3.8.tar.gz #6

hafizmtalha opened this issue Dec 20, 2018 · 3 comments

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@hafizmtalha
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I m trying to install silve, and this tool tries to download and unpack unafold-3.8.tar.gz. But the links it is using seems to be not available anymore. Kindly provide the alternative link.

@buske
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buske commented Dec 20, 2018

Dear @hafizmtalha, unfortunately, the owners of UNAfold have changed the license and stopped distributing it freely. The UNAfold website says you need to obtain the software from ibridge. Unfortunately, there is no other way to download it. To still use SilVA, just use the version without the folding features (which removes the dependency on UNAfold and ViennaRNA): http://compbio.cs.toronto.edu/silva/release/silva-1.1.1-nofolding.tar.gz

@hafizmtalha
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hafizmtalha commented Dec 20, 2018 via email

@rescuz
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rescuz commented Jul 12, 2024

Thanks for your reply. I want to make sure whether the nofolding version of silva-1.1.1 cannot predict the synonymous variants in chrY. Because I met the mention "Removing variants on chromosome Y" in the stdout.
The detailed information labeled below:
"
Found 44535 synonymous variants (1730 dropped)
Removing variants on chromosome Y...
Left with 0 variants...
Annotating with 1000 Genomes Project allele frequency...
Loading optimized table from: /data/Project/AI/methods/scripts/pathogenicity/SYN/silva-1.1.1-nofolding/data/1000gp.refGene.pkl
Filtering by allele frequency [0, 0.05]...
Left with 0 variants...
Annotating with mRNA sequence...
Loading genes from pickled file: /data/Project/AI/methods/scripts/pathogenicity/SYN/silva-1.1.1-nofolding/data/refGene.pkl
Annotating features from MRNA files...
Error encountered! "

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