DESCRIPTION

Package: OptimalGoldstandardDesigns
Type: Package
Title: Design Parameter Optimization for Gold-Standard Non-Inferiority Trials
Version: 1.0.1
Authors@R: c(person("Jan", "Meis", role = c("aut", "cre"), email="meis@imbi.uni-heidelberg.de", comment = c(ORCID = "0000-0001-5407-7220")))
Description: Methods to calculate optimal design parameters
    for one- and two-stage three-arm group-sequential gold-standard
    non-inferiority trial designs
    with or without binding or nonbinding futility boundaries,
    as described in Meis et al. (2023) <doi:10.1002/sim.9630>.
License: GPL (>= 3)
Encoding: UTF-8
Depends:
    R (>= 3.5)
Imports:
    nloptr,
    mvtnorm,
    cli,
    dplyr,
    tibble,
    Rdpack
Suggests: 
    testthat (>= 3.0.0),
    here,
    knitr,
    rmarkdown,
    covr,
    fpCompare,
    mnormt,
    future.apply
Config/testthat/edition: 3
RoxygenNote: 7.2.3
Roxygen: list(markdown = TRUE)
RdMacros: Rdpack
Collate: 
    'OptimalGoldstandardDesigns-package.R'
    'pmv_upper_smaller_slower_fix.R'
    'conditional_probability_functions.R'
    'design_display_functions.R'
    'global_constants.R'
    'design_helper_functions.R'
    'objective_functions.R'
    'optimization_methods.R'
    'table_format_functions.R'
VignetteBuilder: knitr
URL: https://github.com/jan-imbi/OptimalGoldstandardDesigns