diff --git a/marimo/_runtime/runtime.py b/marimo/_runtime/runtime.py
index 27030a0ff67..9c204c6771e 100644
--- a/marimo/_runtime/runtime.py
+++ b/marimo/_runtime/runtime.py
@@ -549,6 +549,13 @@ def _update_runtime_from_user_config(self, config: MarimoConfig) -> None:
         ):
             self.package_manager = create_package_manager(package_manager)
 
+            if self._should_update_script_metadata():
+                # All marimo notebooks depend on the marimo package; if the
+                # notebook already has marimo as a dependency, or an optional
+                # dependency group with marimo, such as marimo[sql], this is a
+                # NOOP.
+                self._update_script_metadata(["marimo"])
+
         if (
             autoreload_mode == "lazy" or autoreload_mode == "autorun"
             # Pyodide doesn't support hot module reloading