diff --git a/courses/migrations/0053_reactivate_wrong_program_enrollments.py b/courses/migrations/0053_reactivate_wrong_program_enrollments.py
new file mode 100644
index 0000000000..4a5ebd7d37
--- /dev/null
+++ b/courses/migrations/0053_reactivate_wrong_program_enrollments.py
@@ -0,0 +1,31 @@
+# Generated by Django 3.2.25 on 2024-08-05 14:45
+
+from django.db import migrations
+
+
+def deactivate_program_enrollments(apps, schema_editor):
+    """Deactivate all Enrollments for this not yet live program 18.03x Differential Equations
+    and activate back for Differential Calculus"""
+    ProgramEnrollments = apps.get_model("courses", "ProgramEnrollment")
+    enrollments = ProgramEnrollments.objects.filter(
+        program__readable_id="program-v1:MITxT+18.01x"
+    )
+    for enrollment in enrollments:
+        enrollment.active = True
+        enrollment.save()
+
+    enrollments = ProgramEnrollments.objects.filter(
+        program__readable_id="program-v1:MITxT+18.03x"
+    )
+    for enrollment in enrollments:
+        enrollment.active = False
+        enrollment.save()
+
+class Migration(migrations.Migration):
+    dependencies = [
+        ("courses", "0052_deactivate_enrollments"),
+    ]
+
+    operations = [
+        migrations.RunPython(deactivate_program_enrollments, migrations.RunPython.noop),
+    ]