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convey PL ~ DP regression model #24

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mlin opened this issue Nov 10, 2020 · 0 comments
Open

convey PL ~ DP regression model #24

mlin opened this issue Nov 10, 2020 · 0 comments
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enhancement New feature or request

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@mlin
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mlin commented Nov 10, 2020

To help with approximate reconstruction of genotype likelihoods from binned DP (when downstream tools strictly require them to be present even in non-variant cells):

  1. during encoding, calculate regression coefficients for PL[1] and PL[2] on binned DP
  2. include them in the output file, perhaps in the header (but that'd require a second pass)
  3. optionally use them to fill out approximate PL vectors during decoding
@mlin mlin added the enhancement New feature or request label Nov 10, 2020
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