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citation.bib
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@ARTICLE{Vogelstein2019mgc,
title = "Discovering and deciphering relationships across disparate data
modalities",
author = "Vogelstein, Joshua T and Bridgeford, Eric W and Wang, Qing and
Priebe, Carey E and Maggioni, Mauro and Shen, Cencheng",
abstract = "Understanding the relationships between different properties of
data, such as whether a genome or connectome has information
about disease status, is increasingly important. While existing
approaches can test whether two properties are related, they may
require unfeasibly large sample sizes and often are not
interpretable. Our approach, 'Multiscale Graph Correlation'
(MGC), is a dependence test that juxtaposes disparate data
science techniques, including k-nearest neighbors, kernel
methods, and multiscale analysis. Other methods may require
double or triple the number of samples to achieve the same
statistical power as MGC in a benchmark suite including
high-dimensional and nonlinear relationships, with dimensionality
ranging from 1 to 1000. Moreover, MGC uniquely characterizes the
latent geometry underlying the relationship, while maintaining
computational efficiency. In real data, including brain imaging
and cancer genetics, MGC detects the presence of a dependency and
provides guidance for the next experiments to conduct.",
journal = "Elife",
volume = 8,
month = jan,
year = 2019,
keywords = "computational biology; data science; human; machine learning;
neuroscience; statistics; systems biology",
language = "en"
}
@techreport{Bridgeford2018_mgcpkg,
author = {Bridgeford, Eric W and Shen, Censheng and Wang, Shangsi and Vogelstein, Joshua},
doi = {10.5281/ZENODO.1246967},
month = {may},
title = {{Multiscale Graph Correlation}},
url = {https://zenodo.org/record/1246967},
year = {2018}
}