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DESCRIPTION
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Package: PathAnalyser
Title: ER & HER2 Pathway Activity Analysis For Breast Cancer
Transcriptomic Datasets
Version: 1.0.0
Authors@R: c(
person("Taniya", "Pal", , "Taniya.Pal.094@cranfield.ac.uk", role = "aut"),
person("Rishabh", "Kaushik", , "rishabh.kaushik.126@cranfield.ac.uk", role = "aut"),
person("Yi-Hsuan", "Lee", , "yi-hsuan.lee@cranfield.ac.uk", role = "aut"),
person("Ozlem", "Karadeniz", , "ozlem.karadeniz.283@cranfield.ac.uk", role = "aut"),
person("Justice", "Iheanyichi", , "j.iheanyichi.616@cranfield.ac.uk", role = "aut"),
person("Anisha", "Thind", , "a.thind@cranfield.ac.uk", role = c("aut", "cre")),
person("Alexey", "Larionov", , "alexey.larionov@cranfield.ac.uk", role = "dgs"),
person("Cranfield University", role = "cph")
)
Description: PathAnalyser provides an assessment of molecular pathway
activity in transcriptomic datasets. The classification algorithm
employed by PathAnalyser implements Gene GSVA to classify samples in a
transcriptomic dataset by pathway activity using a gene signature.
Currently, the package provides built-in data for assessment of ER &
HER2 pathway activity in breast cancer transcriptomic datasets,
however the PathAnalyser functionality could also be applied to gene
signatures and/or transcriptomic datasets in non-oncological contexts.
License: MIT + file LICENSE
URL: https://github.com/ozlemkaradeniz/PathAnalyser
BugReports: https://github.com/ozlemkaradeniz/PathAnalyser/issues
Depends:
GSVA,
R (>= 2.10)
biocView:
Imports:
edgeR,
ggfortify,
ggplot2,
limma,
plotly,
reader,
reshape2
Suggests:
BiocStyle,
knitr,
rmarkdown,
testthat,
magick,
qpdf
VignetteBuilder:
knitr
Encoding: UTF-8
LazyData: true
LazyDataCompression: xz
Roxygen: list(markdown = TRUE)
RoxygenNote: 7.1.2.9000