_r_val_hub_intro.qmd

# 👋 Who We Are {transition="none-in slide-out"}

```{=html}
<style>
.panel {
  font-size: 0.6em;
  background: rgba(0.75, 0.75, 0.75, 0.1);
  padding: 1%;
  margin: 1%;
  border-radius: 0.5em;
  border-bottom: solid 0.2em rgba(1, 1, 1, 0.1);
}

.center {
  --r-heading-margin: auto;
  width: fit-content;
}

.person {
  font-weight: bold;
  font-size: 0.8em;
  margin: 1em 0 0.5em 0;
}

.person p {
  display: inline;
}

.person:before {
  display: inline;
  content: "👤 ";
}

.badge-pill {
  font-weight: bold;
  background: var(--r-link-color);
  color: white;
  border-radius: 1em;
  padding: 0 0.5em;
}
</style>
```

::: { style="font-size: 0.7em;" }
> The ***R Validation Hub*** is a collaboration to support the adoption of R
> within a biopharmaceutical regulatory setting ([pharmaR.org](https://www.pharmaR.org))
:::

* Grew out of **R/Pharma 2018**
* Led by participants from **~10 organizations**
* With frequent involvement from health authorities (primarily the FDA)
* And subscribers from **~60 organizations** spanning multiple industries

## 🤝 Affiliates: ![](assets/camis.png){height="1.2em" width="1.2em" style="margin: 0 0.2em; border-radius: 50%; object-fit: cover; background: #CBC; vertical-align: middle;"} PSI/AIMS (CAMIS) {transition="slide-in slide-out"}

::::: {.columns}
:::: {.column width="65%"}
::: { style="font-size: 0.6em;" }
> **C**omparing **A**nalysis **M**ethod **I**mplementations in **S**oftware  
> A cross-industry group formed of members from PHUSE, PSI, and ASA.
:::

::: { style="font-size: 0.7em;" }
- Released a [white paper](https://phuse.s3.eu-central-1.amazonaws.com/Deliverables/Data+Visualisation+%26+Open+Source+Technology/WP077.pdf) providing guidance on appropriate use of stats methods, for example:
  * Don't default to the defaults
  * Be specific when drafting analysis plans, including precise methods & options
- A resource for knowing the details of methods across languages
:::
::::

:::: {.column width="35%"}
![](assets/CAMIS-white-paper.png)
::::
:::::


## 🤝 Affiliates: ![](assets/camis.png){height="1.2em" width="1.2em" style="margin: 0 0.2em; border-radius: 50%; object-fit: cover; background: #CBC; vertical-align: middle;"} PSI/AIMS (CAMIS) {transition="slide-in slide-out"}

::: {style="font-size: 0.85em"}  
- Currently building a repository of methods comparisons at 
  [psiaims.github.io/CAMIS](https://psiaims.github.io/CAMIS/).
- Check out their 
  [contributors page](https://psiaims.github.io/CAMIS/contribution.html) to 
  learn how you can get involved!

| Methods            |                    | R   | SAS | Comparison |
| ------------------ | ------------------ | --- | --- | -----------|
| Summary Statistics | Rounding           | [`R`](https://psiaims.github.io/CAMIS/R/rounding.html) | [`SAS`](https://psiaims.github.io/CAMIS/SAS/rounding.html) | [`R` vs `SAS`](https://psiaims.github.io/CAMIS/Comp/r-sas_rounding.html) |
|                    | Summary Statistics | [`R`](https://psiaims.github.io/CAMIS/R/summary-stats.html) | [`SAS`](https://psiaims.github.io/CAMIS/SAS/summary-stats.html) | [`R` vs `SAS`](https://psiaims.github.io/CAMIS/Comp/r-sas-summary-stats.html) |
| ... | ... | ... | ... | ... |

: [CAMIS Comparisons Resources](https://psiaims.github.io/CAMIS/)

:::


## 🤝 Affiliates: ![](assets/r-consortium.png){height="1.2em" style="padding: 0.2em; margin: 0 0.5em 0 0; border-radius: 0.8em; background: #FFF; vertical-align: middle;"} [R Consortium]{.hidden} {transition="slide-in slide-out"}

::: {style="font-size: 0.7em"}
> Works with and provides support to the R Foundation and to the key
> organizations developing, maintaining, distributing and using R software
:::

### Key Activities

* The R Validation Hub
* R Submission Working Group
* R Repositories Working Group (ie CRAN enhancements, future development)

## 👷‍♂️ What We Do ([pharmaR.org](https://www.pharmaR.org)) {transition="slide-in slide-out"}

### Products {.center}

::::: {.columns}
:::: {.column width="29%" .panel}
#### White Paper
Guidance on compliant use of R and management of packages
::::

:::: {.column width="29%" .panel}
#### [New!]{.badge-pill} Repositories

Building a public, validation-ready resource for R packages  

::: {.person}
Coline Zeballos
:::
::::

:::: {.column width="29%" .panel}
#### [New!]{.badge-pill} Communications

Connecting validation experts across the industry

::: {.person}
Juliane Manitz
:::
::::
:::::

::::: {.columns}
:::: {.column width="29%" .panel}
#### [`{riskmetric}`](https://github.com/pharmaR/riskmetric)

Gather and report on risk heuristics to support validation decision-making

::: {.person}
Eric Milliman
:::
::::

:::: {.column width="29%" .panel}
#### [`{riskassessment}`](https://github.com/pharmaR/riskassessment)

A web interface to `{riskmetric}`, supporting review,
annotation and cataloging of decisions

::: {.person}
Aaron Clark
:::
::::

:::: {.column width="29%" .panel}
#### [New!]{.badge-pill} [`{riskscore}`](https://github.com/pharmaR/riskscore)

An R data package capturing risk metrics across all of CRAN

::: {.person}
Aaron Clark
:::
::::
:::::