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DESCRIPTION
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Package: netOmics
Title: Multi-Omics (time-course) network-based integration and interpretation
Version: 1.5.1
Authors@R:
person(given = "Antoine", family = "Bodein", role = c("aut", "cre"), email = "antoine.bodein.1@ulaval.ca")
Description: netOmics is a multi-omics networks builder and explorer.
It uses a combination of network inference algorithms and and knowledge-based graphs to build multi-layered networks.
The package can be combined with timeOmics to incorporate time-course expression data and build sub-networks from multi-omics kinetic clusters.
Finally, from the generated multi-omics networks, propagation analyses allow the identification of missing biological functions (1),
multi-omics mechanisms (2) and molecules between kinetic clusters (3). This helps to resolve complex regulatory mechanisms.
License: GPL-3
Encoding: UTF-8
LazyData: false
Roxygen: list(markdown = TRUE)
RoxygenNote: 7.2.3
VignetteBuilder: knitr
Depends: R (>= 4.1)
Imports:
dplyr,
ggplot2,
igraph,
magrittr,
minet,
purrr,
tibble,
tidyr,
AnnotationDbi,
GO.db,
RandomWalkRestartMH,
gprofiler2,
methods,
stats
Suggests:
mixOmics,
timeOmics,
tidyverse,
BiocStyle,
testthat,
covr,
rmarkdown,
knitr
biocViews: GraphAndNetwork, Software, TimeCourse, WorkflowStep, SystemsBiology, NetworkInference, Network
URL: https://github.com/abodein/netOmics
BugReports: https://github.com/abodein/netOmics/issues