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Update src/docs/multiomics_submission.md
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Co-authored-by: Sandy Rogers <sandyr@ebi.ac.uk>
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Ales-ibt and SandyRogers authored Mar 5, 2024
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Expand Up @@ -37,7 +37,7 @@ A useful feature of the BioSamples repository is that samples generated from the

The HoloFood project adopts a 'hologenomic' approach to enhance the efficiency of food production systems. This approach focuses on comprehending the biomolecular and physiological processes influenced by integrating feed additives and innovative sustainable feeds in farm animals. Holofood leverages various cutting-edge technologies to explore the intricate interactions between animals and their respective gut microbiomes on multiple molecular levels. Samples and data generated by the HoloFood project can be accessed through the [Holofood Data Portal](https://www.holofooddata.org/).

Multi-omics data generated from both animal host and microbiome, along with physiochemical and physiological data, have been deposited into the BioSamples database and other relevant repositories. To avoid multiple levels of nested relationships, the authors opt for assigning a BioSamples ID to each animal and linking it to the corresponding biological samples through ‘DERIVED FROM’ relationships. For instance, animal [`SAMEA112905287`](https://www.ebi.ac.uk/biosamples/samples/SAMEA112905287) has 8 derived samples with external links to other repositories when relevant (see [Figure 2](@SAMEA112905287_example)). Examples of samples with “derived from” relationships to animal `SAMEA112905287` are host genomics (linked to the ENA), metagenomic assembly (linked to the ENA), and metabolomic (linked to MetaboLights). Other animal samples can also have associated transcriptomics (ENA), metatranscriptomics (ENA), inflammatory markers (stored in BioSamples), or histological data (stored in BioSamples).
Multi-omics data generated from both animal host and microbiome, along with physiochemical and physiological data, have been deposited into the BioSamples database and other relevant repositories. To avoid multiple levels of nested relationships, the authors opt for assigning a BioSamples ID to each animal and linking it to the corresponding biological samples through ‘DERIVED FROM’ relationships. For instance, animal [`SAMEA112905287`](https://www.ebi.ac.uk/biosamples/samples/SAMEA112905287) has 8 derived samples with external links to other repositories when relevant (see (@SAMEA112905287_example)). Examples of samples with “derived from” relationships to animal `SAMEA112905287` are host genomics (linked to the ENA), metagenomic assembly (linked to the ENA), and metabolomic (linked to MetaboLights). Other animal samples can also have associated transcriptomics (ENA), metatranscriptomics (ENA), inflammatory markers (stored in BioSamples), or histological data (stored in BioSamples).

[Figure 2. Example of an animal sample having multiple derived samples associated with it](images/multiomics/SAMEA112905287_example.png){#SAMEA112905287_example .tall-figure fig-align="left"}

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