Giant burrowing mayflies are aquatic insects that have a unique life history. Found throughout North America, these insects emerge by the thousands from lakes and streams throughout the spring and summer to breed. The life of adult mayflies is short-lived—only two days! Females can produce up to 8000 eggs, which are laid on the water’s surface and then sink to the bottom. Naiads (newly-hatched mayflies) live in the water for several months before they emerge, beginning the cycle again.
2024/12/23 - 12/25: study https://www.als.org/
2024/12/26 7:00 - 12/29 11:25: study https://en.wikipedia.org/wiki/ALS
2024/12/29 14:22 - 12/31 23:56: study the paper "RAG-17: A Novel siRNA Conjugate Demonstrating Efficacy in Late-Stage Treatment of SOD1G93A ALS mice"
2025/1/1 0:42 - 1/2 23:50: Intrathecal administration of a novel siRNA modality extends survival and improves motor function in the SOD1G93A ALS mouse model
(why so slow)2025/1/2 23:50 - 1/10 12:00: study the news: SNUG01 is an innovative gene therapy drug developed by Shenji Changhua based on the endogenous neuroprotective molecule SG001 and using adeno-associated virus (AAV) as a vector.
2025/1/10 12:00 - : Khan Academy: High school biology
- 2025/1/10 17:19 - : Unit 1: Unit 1: Ecology and natural systems
2025/1/1 - 1/20 goals: I will continue to study based on the official website: first study the drug pipeline (clinical stage), then the drug pipeline (preclinical stage), followed by preclinical basic research, and then the monthly work updates. I aim to learn all the knowledge on the official website within 20 days (by January 20, 2025) and keep up with the work progress of Cai Lei's team.
To accomplish something, a good plan only accounts for 5%; the remaining 95% depends on how you execute it and how you adjust on the fly according to the actual situation.
“Study hard what interests you the most in the most undisciplined, irreverent and original manner possible.” — Richard P. Feynman
打败死神, 获得永生, 征服宇宙。 有AI的帮助, 人类可以早日实现这些目标。反正我有太多的东西要学, 有太多的事情要做。当然人生短短几十年, 想怎么活, 是个人选择问题, 自己想清楚了, 临死的时候不后悔就够了
Running shirtless in the cold winter wind was incredibly refreshing. Kolmogorov, in his sixties or seventies, could still ski shirtless in the dead of winter, compete with young people, swim in cold water, boxing, and hike for dozens of kilometers. Kolmogorov also advised his students to swim several kilometers before studying mathematics. In terms of academic achievement, I can't compare to Kolmogorov, but in physical fitness, I'd really like to arm wrestle him. I remember an American statistician once said: 'I came to the Soviet Union to find out one thing - is Kolmogorov a person or an entire research institute?' Kolmogorov's productivity is astonishing, but from my analysis, he spent at least a quarter of his life on physical exercise. I firmly believe that physical exercise and high productivity do not conflict; on the contrary, physical exercise aids in the generation and development of brain neurons, thereby promoting more efficient learning and work.
Either die amid endless internal competition or perish while venturing into the unknown. Two ways to die—choose one.