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alias:: APSGN, AGN | ||
ICD-11_Code:: | ||
|
||
- ## Etiology | ||
background-color:: blue | ||
- ### Causative Agents | ||
- Group A beta haemolytic streptococci (past infections) | ||
- ### Risk Factors | ||
- ## Epidemiology | ||
background-color:: blue | ||
- ### Incidence | ||
- ### Prevalence | ||
- ### Demographics | ||
- Age: 5-12 years | ||
- Uncommon before 3 years | ||
- ### Geographic Distribution | ||
- ## Pathophysiology | ||
background-color:: blue | ||
- ### Mechanism of Disease | ||
- After infection y group A beta haemolytic streptococci, antibody produced against the streptococcal antigens. | ||
- Antigen-antibody complexes are thus formed in the blood, deposited in the glomeruli, where they incite glomerular inflammation and activate the complement cascade. | ||
- As a result of this inflammation, the following clinico-pathological events occur | ||
- ### Affected Systems/Organs | ||
- ((67384d80-0fa9-407a-bf72-a40fed3e85c6)) | ||
- ## Clinical Features | ||
background-color:: blue | ||
- ### Signs and Symptoms | ||
- #### Symptoms | ||
- History of skin or throat infection: May be present, 1-6 weeks prior to disease manifestations. | ||
- Variable manifestations related to severity of renal involvement ranging from | ||
- Asymptomatic microscopic haematuria with normal renal function to acute kidney injury (AKI) | ||
- Scanty high coloured urine, may have anuria | ||
- Puffiness of face | ||
- Fever: Uncommon, but may have low grade fever | ||
- Non-specific symptoms : malaise, lethargy, headache or vomiting may be present | ||
- Sometimes, patients may present with features of comolications like | ||
- ((67384e8c-b398-4d12-99be-78ae8deece2d)) | ||
- #### Signs | ||
- Periorbital swelling, and of face also | ||
- Pallor : Mild | ||
- Skin : Evidence of [[Scabies]] or Scars of previous infected scabies | ||
- Oedema : Present | ||
- Blood Pressure : High | ||
- Features of [[Left Heart Failure]] | ||
- ### Stages or Classification | ||
- ### Diagnostic Criteria | ||
- Based on typical C/F and supportive laboratory findings. | ||
- ## Diagnosis | ||
background-color:: blue | ||
- ### Clinical Diagnosis | ||
- #### Classical Presentation | ||
- Evidence of Edema with History of Sore Throat examination | ||
- Associated with scabies | ||
- High Blood Pressure | ||
- Features of [[Left Heart Failure]], [[Hypertensive Encephalopathy]], [[Renal Failure]] | ||
- #### Probable Diagnosis | ||
- ### Laboratory Tests | ||
- ((67385fe9-5fab-4115-843c-17cd3c424e76)) | ||
- ### Imaging Studies | ||
- ((67385ffd-3281-4b85-86ec-8a36c9df2689)) | ||
- ### Differential Diagnosis | ||
- ### Confirmation of Diagnosis | ||
- ## Management and Treatment | ||
background-color:: blue | ||
- ### Counselling | ||
- Counsel parents about the nature of the disaese, its complications, treatment and prognosis | ||
- ### Medical Treatment | ||
- Bed Rest | ||
- Diet : Restriction of | ||
- Protein to 0.5 gm/kg/day | ||
- Salt : No added salt in the diet | ||
- Potassium ($$\ce{K+}$$) & $$\ce{K+}$$ rich food and fruits | ||
- Fluid : 400 $$ml/m^2$$ + Output of previous day | ||
- Diuretics : Frusemide (1-2 mg/kg/day) | ||
- Antibiotics | ||
- Oral Phenoxymethyl Penicillin (50 mg/kg/day) in 4 divided doses for 10 days | ||
- >Penicillin does not alter the course of the disease but it prevents spreading of remaining nephritogenic strain of sreptococcus to the contacts | ||
- Antihypertensives | ||
- For rapid reduction of BP | ||
- Nifedipine (0.3-0.5 mg/kg) sublingual | ||
- For maintenance of normal BP | ||
- Captopril (0.25-6 mg/kg/day) in 2-4 doses | ||
- Nifedipine (0.25-0.5 mg/kg/day) in 2-4 doses | ||
- ### Surgical Options | ||
- ### Lifestyle and Dietary Recommendations | ||
- ### Follow-up | ||
- Daily to assess clinical response and to search for any complications | ||
- ## Prognosis | ||
background-color:: blue | ||
- ### Expected Course | ||
- #### With Treatment | ||
- complete recovery in >95% cases | ||
- Recurrence is rare | ||
- #### Without Treatment | ||
- ### Survival Rates | ||
- #### With Treatment | ||
- #### Without Treatment | ||
- ### Quality of Life Considerations | ||
- ## Complications | ||
background-color:: blue | ||
- ### Possible Complications | ||
- ### Long-term Effects | ||
- ## Prevention | ||
background-color:: blue | ||
- ### Health Education | ||
- ### Community Approach | ||
- ### Screening Programs | ||
- ### Lifestyle Modifications | ||
- ## Patient Education and Support | ||
background-color:: blue | ||
- ### Educational Resources | ||
- ### Support Groups | ||
- ### Counseling Options | ||
- ## Recent Research and Developments | ||
background-color:: blue | ||
- ### Ongoing Clinical Trials | ||
- ### Recent Advances | ||
- ## Key Literature | ||
background-color:: blue | ||
- ## Guidelines and Protocols | ||
background-color:: blue |
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- alias:: | ||
ICD-11_Code:: | ||
- ## Etiology | ||
background-color:: blue | ||
- ### Causative Agents | ||
- ### Risk Factors | ||
- ## Epidemiology | ||
background-color:: blue | ||
- ### Incidence | ||
- ### Prevalence | ||
- ### Demographics | ||
- ### Geographic Distribution | ||
- ## Pathophysiology | ||
background-color:: blue | ||
- ### Mechanism of Disease | ||
- ### Affected Systems/Organs | ||
- ## Clinical Features | ||
background-color:: blue | ||
- ### Signs and Symptoms | ||
- #### Symptoms | ||
- #### Signs | ||
- ### Stages or Classification | ||
- ### Diagnostic Criteria | ||
- ## Diagnosis | ||
background-color:: blue | ||
- ### Clinical Diagnosis | ||
- #### Classical Presentation | ||
- #### Probable Diagnosis | ||
- ### Laboratory Tests | ||
- ### Imaging Studies | ||
- [[ECG]] | ||
- Low voltage | ||
- Poor R wave progression | ||
- Tall P waves | ||
- Unusual QRS axis | ||
- ### Differential Diagnosis | ||
- ### Confirmation of Diagnosis | ||
- ## Management and Treatment | ||
background-color:: blue | ||
- ### Medical Treatment | ||
- ### Surgical Options | ||
- ### Lifestyle and Dietary Recommendations | ||
- ### Follow-up | ||
- ## Prognosis | ||
background-color:: blue | ||
- ### Expected Course | ||
- #### With Treatment | ||
- #### Without Treatment | ||
- ### Survival Rates | ||
- #### With Treatment | ||
- #### Without Treatment | ||
- ### Quality of Life Considerations | ||
- ## Complications | ||
background-color:: blue | ||
- ### Possible Complications | ||
- ### Long-term Effects | ||
- ## Prevention | ||
background-color:: blue | ||
- ### Health Education | ||
- ### Community Approach | ||
- ### Screening Programs | ||
- ### Lifestyle Modifications | ||
- ## Patient Education and Support | ||
background-color:: blue | ||
- ### Educational Resources | ||
- ### Support Groups | ||
- ### Counseling Options | ||
- ## Recent Research and Developments | ||
background-color:: blue | ||
- ### Ongoing Clinical Trials | ||
- ### Recent Advances | ||
- ## Key Literature | ||
background-color:: blue | ||
- ## Guidelines and Protocols | ||
background-color:: blue |
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Original file line number | Diff line number | Diff line change |
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@@ -0,0 +1,72 @@ | ||
- alias:: | ||
ICD-11_Code:: | ||
- ## Etiology | ||
background-color:: blue | ||
- ### Causative Agents | ||
- ### Risk Factors | ||
- ## Epidemiology | ||
background-color:: blue | ||
- ### Incidence | ||
- ### Prevalence | ||
- ### Demographics | ||
- ### Geographic Distribution | ||
- ## Pathophysiology | ||
background-color:: blue | ||
- ### Mechanism of Disease | ||
- ### Affected Systems/Organs | ||
- ## Clinical Features | ||
background-color:: blue | ||
- ### Signs and Symptoms | ||
- #### Symptoms | ||
- #### Signs | ||
- ### Stages or Classification | ||
- [[Hepatic Encephalopathy]] | ||
- [[Hypertensive Encephalopathy]] | ||
- ### Diagnostic Criteria | ||
- ## Diagnosis | ||
background-color:: blue | ||
- ### Clinical Diagnosis | ||
- #### Classical Presentation | ||
- #### Probable Diagnosis | ||
- ### Laboratory Tests | ||
- ### Imaging Studies | ||
- ### Differential Diagnosis | ||
- ### Confirmation of Diagnosis | ||
- ## Management and Treatment | ||
background-color:: blue | ||
- ### Medical Treatment | ||
- ### Surgical Options | ||
- ### Lifestyle and Dietary Recommendations | ||
- ### Follow-up | ||
- ## Prognosis | ||
background-color:: blue | ||
- ### Expected Course | ||
- #### With Treatment | ||
- #### Without Treatment | ||
- ### Survival Rates | ||
- #### With Treatment | ||
- #### Without Treatment | ||
- ### Quality of Life Considerations | ||
- ## Complications | ||
background-color:: blue | ||
- ### Possible Complications | ||
- ### Long-term Effects | ||
- ## Prevention | ||
background-color:: blue | ||
- ### Health Education | ||
- ### Community Approach | ||
- ### Screening Programs | ||
- ### Lifestyle Modifications | ||
- ## Patient Education and Support | ||
background-color:: blue | ||
- ### Educational Resources | ||
- ### Support Groups | ||
- ### Counseling Options | ||
- ## Recent Research and Developments | ||
background-color:: blue | ||
- ### Ongoing Clinical Trials | ||
- ### Recent Advances | ||
- ## Key Literature | ||
background-color:: blue | ||
- ## Guidelines and Protocols | ||
background-color:: blue |
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- Causes | ||
- [[AGN]] | ||
- [[IgA Nephropathy]] | ||
- [[Renal Tuberculosis]] | ||
- [[Renal calculi]] | ||
- [[Wilms Tumour]] | ||
- [[Coagulopathy]] | ||
- [[SLE]], [[HSP]], [[UTI]] |
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