fever and murphy

kamranmuazzam · Oct 9, 2024 · 5ea6a0f · 5ea6a0f
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diff --git a/assets/2-Figure1-1_1728441460583_0.png b/assets/2-Figure1-1_1728441460583_0.png
diff --git a/pages/Fever.md b/pages/Fever.md
@@ -1,12 +1,12 @@
 alias:: hyperthermia,  pyrexia
-definition:: A body temperature of 38 ºC or higher is considered a fever
+definition:: A body temperature of 38 ºC (100.4 ºF) or higher is considered a fever
 
-- Associations
+- ## Associations
+  collapsed:: true
 	- Associated Signs and Symptoms
 		- | **Symptom** | **Sensitivity (%)** | **Specificity (%)** |
-		  | ---- | ---- | ---- |
+		  |--|--|--|
 		  | **Headache** | 60 - 70% | 50 - 60% |
-		  | **Myalgia** | 50 - 60% | 70 - 80% |
 		  | **Chills / Shivering** | 40 - 60% | 60 - 70% |
 		  | **Fatigue** | 50 - 70% | 40 - 50% |
 		  | **Nausea** | 20 - 40% | 60 - 70% |
@@ -15,46 +15,72 @@ definition:: A body temperature of 38 ºC or higher is considered a fever
 		  | **Loss of Appetite** | 40 - 60% | 50 - 60% |
 		  | **Dizziness** | 10 - 20% | 50 - 60% |
 		  | **Dehydration** | 20 - 40% | 60 - 70% |
-		- | **Symptom** | **Sensitivity (%)** (People with fever who have the symptom) | **Specificity (%)** (People with the symptom who develop fever) |
-		  | ---- | ---- | ---- | ---- |
-		  | **Headache** | 60 - 70% | 50 - 60% |
-		  | **[[Myalgia]]** | 50 - 60% | 70 - 80% |
-		  | **Chills / Shivering** | 40 - 60% | 60 - 70% |
-		  | **Fatigue** | 50 - 70% | 40 - 50% |
-		  | **Nausea** | 20 - 40% | 60 - 70% |
-		  | **Vomiting** | 15 - 30% | 70 - 80% |
-		  | **Sweating** | 30 - 50% | 50 - 60% |
-		  | **Loss of Appetite** | 40 - 60% | 50 - 60% |
-		  | **Dizziness / Lightheadedness** | 10 - 20% | 50 - 60% |
-		  | **Dehydration** | 20 - 40% | 60 - 70% |
 	- Associated conditions
-		- | **Condition** | **Sensitivity (%)** | **Specificity (%)** |
-		  | ---- | ---- | ---- |
-		  | **Infections (Overall)** | 90 - 95% | 85 - 90% |
-		  | **Viral Infections** | 80 - 90% | 60 - 70% |
-		  | **Bacterial Infections** | 70 - 80% | 75 - 85% |
-		  | **Fungal and Parasitic Infections** | 40 - 60% | 80 - 90% |
-		  | **Inflammatory Conditions** | 20 - 40% | 90 - 95% |
-		  | **Autoimmune Diseases (e.g., Lupus)** | 20 - 30% | 95% |
-		  | **Inflammatory Bowel Disease** | 10 - 20% | 90 - 95% |
-		  | **Heat-related Illness (Heatstroke)** | 60 - 70% | 80 - 90% |
-		  | **Drug Reactions / Fever** | 5 - 10% | 95% |
-		  | **Cancer (e.g., Hematologic)** | 10 - 20% | 90 - 95% |
-		  | **Endocrine Disorders (e.g., Hyperthyroidism)** | 5 - 10% | 90 - 95% |
-		  | **Post-vaccination Fever** | 1 - 5% | 95 - 98% |
-		- | **Condition** | **Sensitivity (%)** (People with fever who have the condition) | **Specificity (%)** (People with the condition who develop fever) |
-		  | ---- | ---- | ---- | ---- |
-		  | **Infections (Overall)** | 90 - 95% | 85 - 90% |
-		  | **Viral Infections** | 60 - 70% | 80 - 90% |
-		  | **Bacterial Infections** | 20 - 30% | 70 - 80% |
-		  | **Fungal and Parasitic Infections** | 5 - 10% | 40 - 60% |
-		  | **Inflammatory Conditions** | 10 - 20% | 20 - 40% |
-		  | **Autoimmune Diseases (e.g., Lupus)** | 5 - 10% | 20 - 30% |
-		  | **Inflammatory Bowel Disease** | 2 - 5% | 10 - 20% |
-		  | **Heatstroke** | 5 - 10% | 100% |
-		  | **Drug Reactions / Fever** | 1 - 3% | 5 - 10% |
-		  | **Cancer (e.g., Hematologic)** | 1 - 2% | 10 - 20% |
-		  | **Endocrine Disorders (e.g., Hyperthyroidism)** | <1% | 5 - 10% |
-		  | **Post-vaccination Fever** | <1% | 1 - 5% |
+		- | **Condition** | **Sensitivity (%)**| **Specificity (%)**  |**Association**|
+		  |--|--|--|--|
+		  | **Infections (Overall)** | 90 - 95% | 85 - 90% |85-90%|
+		  | **Viral Infections** | 60 - 70% | 60 - 70% |80-90%|
+		  | **Bacterial Infections** | 20 - 30% | 70 - 80% |75-85%|
+		  | **Fungal and Parasitic Infections** | 5 - 10% | 40 - 60% |80-90%|
+		  | **Inflammatory Conditions** | 10 - 20% | 20 - 40% |90-95%|
+		  | **Autoimmune Diseases (e.g., Lupus)** | 5 - 10% | 20 - 30% |95%|
+		  | **Inflammatory Bowel Disease** | 2 - 5% | 10 - 20% |90-95%|
+		  | **Heatstroke** | 5 - 10% | 100% |100%|
+		  | **Drug Reactions / Fever** | 1 - 3% | 5 - 10% |95%|
+		  | **Cancer (e.g., Hematologic)** | 1 - 2% | 10 - 20% |90-95%|
+		  | **Endocrine Disorders (e.g., Hyperthyroidism)** | <1% | 5 - 10% |90-95%|
+		  | **Post-vaccination Fever** | <1% | 1 - 5% |95-98%|
 - > Note : A fever is not an illness by itself, but, rather, a sign that something is not right within the body.
--
+- ## Classification
+	- |Type of Fever|Temperature|
+	  |--|--|
+	  |Low-grade Fever|100.4 ºF - 102.2 ºF (38 ºC - 39 ºC)|
+	  |Moderate Fever|102.2 ºF - 104 ºF (39 ºC - 40 ºC)|
+	  |High Fever|>104 ºF (>40 ºC)|
+	- |Type of Fever|Duration|
+	  |--|--|
+	  |Acute Fever|<7 days|
+	  |Subacute Fever|7-14 days|
+	  |Chronic Fever|>14 days|
+	- |Type of Fever|Pattern|
+	  |--|--|
+	  |Intermittent Fever|Fever episodes alternate with periods of normal temperature (e.g., [[Malaria]]).|
+	  |Remittent Fever|Fever fluctuates but does not return to normal (e.g., [[Typhoid]] )|
+	  |Continuous Fever|Fever remains consistently elevated (e.g., [[Pneumonia]] )|
+	  |Relapsing Fever|Episodes of fever occur intermittently with periods of normal temperature (e.g., [[Lyme Disease]] )|
+	- TODO Replasing Fever example
+	  :LOGBOOK:
+	  CLOCK: [2024-10-09 Wed 08:31:20]--[2024-10-09 Wed 08:31:21] =>  00:00:01
+	  CLOCK: [2024-10-09 Wed 08:31:21]--[2024-10-09 Wed 08:31:21] =>  00:00:00
+	  CLOCK: [2024-10-09 Wed 08:31:25]--[2024-10-09 Wed 08:31:25] =>  00:00:00
+	  :END:
+	-
+- ## Pathophysiology
+	- ![2-Figure1-1.png](../assets/2-Figure1-1_1728441460583_0.png){:height 591, :width 301}
+- ## Symptomatic Management
+  collapsed:: true
+	- Pharmacolgical
+		- Antipyretics
+			- [[Paracetamol]]
+			- [[NSAIDS]]
+		- [[Corticosteroids]]
+		- [[Antibiotics]]
+	- Non Pharmacological
+		- Hydration
+		- Physical Cooling Methods
+			- Luke-warm sponge baths
+				- avoid cold baths, as it can cause shivering and rise in temperature (do not submerge in ice bath even if sever rise of temperature, this is not a move, and it can be counterintuitive)
+				- avoid alcohol application all over the body, this can lead to alcohol poisoning
+				- monitor for shivering
+			- Cooling baths, sponge (forehead, neck, armpits, groin)
+		- Comfort Measures
+			- Rest
+			- Light Clothing
+		- Ventilation
+		- Diet : easily digestible food, focus on nutrition & hydration
+- ## Complications
+	- Dehydration
+	- Febrile seizures in young children
+	- Organ Dysfucntion
+	- Rhabdomyolysis
+	- Hyperthermia
diff --git a/pages/Murphy's Sign.md b/pages/Murphy's Sign.md
@@ -0,0 +1,16 @@
+- Procedure
+	- Patient Positioning : Usually lying in supine position
+	- Four of digits of left hand are placed parallel to the lower ribs, while the thumb is pressed on the the intersection of midclavicular line and transplyloric plane
+	- Patient is asked to take a deep breath
+- Murphy's Sign is positive if the patient experiences pain and abruptly stops inhaling due to tenderness (catch hold breathing)
+- Positive Interpretation
+	- [[Acute cholecystitis]]
+- False Positives
+	- Acute Hepatitis
+	- Liver abscess
+	- Perihepatic abscess
+	- Perforated peptic ulcer
+	- Pancreatitis (rare)
+- Sensitivity & Specificity
+	- Sensitivity : 60-97%
+	- Specificity : 80-95%
diff --git a/pages/Sings & Symptoms.md b/pages/Sings & Symptoms.md
@@ -1,4 +1,4 @@
-- LATER [[Fever]]
+- DONE [[Fever]]
   :LOGBOOK:
   CLOCK: [2024-10-08 Tue 23:59:33]--[2024-10-08 Tue 23:59:34] =>  00:00:01
   CLOCK: [2024-10-08 Tue 23:59:36]--[2024-10-08 Tue 23:59:37] =>  00:00:01

diff --git a/pages/Typhoid Fever.md b/pages/Typhoid Fever.md
@@ -1,4 +1,4 @@
-alias:: Enteric Fever
+alias:: Enteric Fever, Typhoid
 
 - ICD-11 Code:
 - ## Etiology