signs & symptoms starting and some minor changes

assets/Symptom_to_Diagnosis_An_Evidence_Based_Guide_1725966752688_0.edn

@@ -32,4 +32,4 @@
                           :page 324},
                :content {:text "Edema"},
                :properties {:color "red"}}],
- :extra {:page 6}}
+ :extra {:page 324}}

logseq/.recycle/journals_2024_09_03.md

@@ -0,0 +1,2 @@
+-
+-

logseq/.recycle/journals_2024_10_08.md

@@ -0,0 +1,2 @@
+-
+-

pages/Advanced Medical Sciences.md

@@ -1,4 +1,6 @@
 - [[Medicine]]
 - [[Surgery]]
 - [[Gynaecology & Obsetrics]]
-- [[Disease]]
+- [[Disease]]
+- LATER [[Sings & Symptoms]]
+-

pages/Clubbing.md

@@ -0,0 +1,53 @@
+definition:: It is the bulbous enlargement of the terminal phalanges due to proliferation of connective tissue.
+
+- Grades of Clubbing
+	- |Grade||Features|
+	  |--|--|--|
+	  |Grade 1|Fluctuation|Normal Appearance and Angle Nail bed Fluctuation|
+	  |Grade 2|Obliteration|Obliteration of Lovibond angle|
+	  |Grade 3|Drumstick|Increased Curvature of Nails, Parrot Beak or Drumstick Appearance|
+	  |Grade 4|HPOA|Swelling in all Directions Hypertrophic Osteoarthropathy|
+- Pathophysiology
+	- Neurogenic
+	- Hypoxia
+		- lower oxygenation of tissue causes VEGF which increases neovasculature
+	- Platelet derived growth factor
+		- Megakaryocytes in normal physiology enter the pulmonary capillaries and split into smaller platelets
+		- If they skip pulmonary capillaries due to Pathology of Lung, it gets clogged in the systemic capillaries, which then causes release of PDGF and VEGF
+	- Mutation
+		- Mutation of HPGD Gene (Autosomal Dominant)
+		- Dysfunction of 15 PGDH enzyme
+		- Failure to metabolize PGE2
+		- Increased blood flow, and connective tissue proliferation
+- Etiology
+	- Respiratory
+		- Bronchial Carcinoma (more commonly large cell than small cell)
+		- Chronic suppurative lung disease
+			- Bronchiectasis
+			- Lung Abscess
+			- Chronic empyema
+		- Pulmonary Fibrosis
+			- Idiopathic pulmonary fibrosis
+			- Cystic fibrosis
+			- Fibrosing Alveolitis
+		- Asbestosis
+		- Sarcoidosis
+	- Cardiac
+		- Fallot Tetralogy
+		- Eisenmenger Syndrome
+		- Subactute Bacterial Endocarditis
+		- Left Atrial Myxoma
+	- GI
+		- IBD
+		- Cirrhosis
+		- Coliac Disease
+		- GI Lymphoma
+		- PBC
+	- Idiopathic
+		- Familial usually before puberty
+	- Rare
+		- Thyroid Acropachy
+		- Pregnancy
+		- Unilateral clubbing
+		- Bronchial arteovenous aneurysm
+		- Axillary artery aneurysm

pages/Euler's Formula.md

@@ -0,0 +1,16 @@
+- $$z = \cos\theta + i\sin\theta$$
+- $$\frac{dz}{d\theta} = -\sin\theta + i\cos\theta$$
+-
+- $$\frac {dz}{d\theta} = i\cos\theta + i^2 \sin \theta$$
+- $$\frac {dz}{d\theta} = i (\cos\theta + i\sin\theta)$$
+- $$\frac {dz}{d\theta} = iz$$
+- $$\frac {1} {z} \space dz = i \space d\theta$$
+- $$\ln(z) = i \theta + c$$
+- if, $\theta = 0$, then,  $z = \cos\theta + i\sin\theta = 1$
+	- $\ln(1) = i \cdot 0 + c$
+	- $\therefore c = 0$
+	-
+-
+- $$\ln(z) = i \theta$$
+- $$z = e^{i\theta} $$
+- $$e^{i\theta} = \cos\theta + i\sin\theta$$

pages/Homines.md

@@ -0,0 +1,73 @@
+- Alexander Fleming
+- Alexander Ogston
+	- Scottish surgeon
+- Antoni Van Leeuwenhoek
+- Atkins
+- Blaise Pascal
+	- `Experience favors the mind prepared`
+- Cecil B. DeMille
+	- In Hollywood, he created sagas
+- Celsus
+	- Roman Encyclopedist, 1st Century AD
+- Charles Mantoux
+	- French Physician
+- Christie
+- Claude Bernard
+- Clemens von Priquitto
+- Councilman
+- Dr Jilani
+	- `Autoimmunity is the cause while Hypersensitivity is the effect` (Autoimmunity ⇒ Hypersensitivity)
+- Fannie Eilshemius
+- Ferdinand Cohn
+- Friedrich August von Hayek
+	- `We shall not grow wiser before we learn that much that we have done was very foolish`
+- George M. Sternberg
+- Ignaz Semmelweis
+	- `The battle against childbed fever... has cost me the best years of my life... But despite all the opposition, I will not give up the struggle... for I believe with unshakeable conviction that the truth will finally triumph`
+		- Hungarian Academy of Sciences (1865)
+	-
+	- Semmelweis reflex
+- John Tyndall
+- Joseph Lister
+- Lafleur
+- Lambl
+- Losch
+- Louis Pasteur
+	- [~Father of](https://www.remnote.com/doc/maW5zBBhnMwDsQNLf?isPin=false) [Moder Microbiology](https://www.remnote.com/doc/N9UM40q9QvekIG4hQ?isPin=false)
+- Munch Petersen
+- Namira Yamin Ylma
+	- `Manush bodlayena`
+	- `Dudh vaat kahini`
+- Paul Elrich
+	- invented salvarsan
+		- against syphilis
+		- was denounced by church claiming that he brought cure for a punishment from god
+	- chain theory
+- Plato
+	- `Ἐν μὲν οὖν τῇ διαλεκτικῇ οὐ τὸ σκότος οὐδὲ τὸ φῶς ζητεῖ ὁ φιλόσοφος γνῶναι, ἀλλὰ τὸ αὐτὸ τἀγαθόν`
+		- In the dialectic, the philosopher does not seek knowledge of darkness or light, but rather the knowledge of the Good itself.
+- Robert Hooke
+- Robert Koch
+- Rudolph Virchow
+	- [~Father of](https://www.remnote.com/doc/maW5zBBhnMwDsQNLf?isPin=false) [Pathology](https://www.remnote.com/doc/mstqo3aJXMAhF9NH2?isPin=false)
+	- All diseases are alterations of normal Histology
+	- omnis cellula e cellula
+		- every cell stems from another cell
+		- modification of cell theory in [[01-06-1858]]
+- Sir Isaac Newton
+	- If I have seen further it is by standing on the shoulders of Giants.
+	- `Corpus omne perseverare in statu suo quiescendi vel movendi uniformiter in directum, nisi quatenus a viribus impressis cogitur statum illum mutare.`
+		- Every body perseveres in its state of rest, or of uniform motion in a right line, unless it is compelled to change that state by forces impressed thereon.
+	- `Mutationem motus proportionalem esse vi motrici impressae, et fieri secundum  lineam rectam qua vis illa imprimitur`
+		- The alteration of motion is ever proportional to the unbalanced force impressed; and is made in the direction of the right line in which that force is impressed.
+	- `Actioni contrariam semper et æqualem esse reactionem: sive corporum duorum actiones in se mutuo semper esse æquales et in partes contrarias dirigi.`
+		- To every action there is always opposed an equal reaction; or the mutual actions of two bodies upon each other are always equal, and directed to contrary parts.
+- Thomas Sowell
+	- American Economist
+	- `There are no solutions; there are only trade-offs`
+- Walther Hesse
+- William Oslar
+- Zacharias Janssen
+- Émile Zola
+	- French novelist
+	- `We are like books. Most people only see our cover, the minority read only the introduction, many people believe the critics. Few will know our content.`

pages/Infectious Disease.md

@@ -0,0 +1,2 @@
+- [[Varicella]]
+-

pages/Mathematics.md

@@ -0,0 +1,2 @@
+- [[Rate Change]]
+- [[Euler's Formula]]

pages/Medicine.md

@@ -5,4 +5,4 @@
 - Clinical Presentations
 	- [[Edema]]
 	- [[Clubbing]]
-	-
+- [[Infectious Disease]]

pages/Rate Change.md

@@ -0,0 +1,11 @@
+- $x$ is the amount of substance
+- $$R \propto x$$
+- $$R = k \cdot x$$
+- $$\frac {dx} {dt} = k \cdot x$$
+- $$\frac {1} {x} dx = k \cdot dt$$
+- in time t, that is from time 0 to time t, the concentration changes from $x_0$ to $x$
+- $$\int_{x_0}^{x} \frac {1} {x} dx = \int_0^t k \cdot dt$$
+- $$\ln(x)-\ln(x_0) = k \cdot t$$
+- $$\ln(\frac {x} {x_0} ) = k \cdot t$$
+- $$\frac {x} {x_0} = e^{k \cdot t}$$
+- $$x = x_0 \cdot e^{k \cdot t}$$

pages/SLE.md

@@ -23,7 +23,7 @@ ICD-11_Code::
 - ## Clinical Features
 	- ### Signs and Symptoms
 		- #### Symptoms
-			- [[Seizures]] and [[Fever]] } in **children**
+			- LATER [[Seizures]] and [[Fever]] } in **children**
 			- [[Raynaud's Phenomenon]] and [[Pleuritis]] } **twice** as common in **adults**
 		- #### Signs
 			- [[Malar Rash]]
@@ -37,7 +37,7 @@ ICD-11_Code::
 	- ### Diagnostic Criteria
 - ## Diagnosis
 	- ### Clinical Diagnosis
-		- Classical Triad of [[Fever]], [[Join Pain]], [[Rash]] in a woman of child bearing age
+		- LATER Classical Triad of [[Fever]], [[Join Pain]], [[Rash]] in a woman of child bearing age
 		- **Constitutional** (eg, fatigue, fever, arthralgia, weight changes)
 		- **Musculoskeletal** (eg, arthralgia, arthropathy, myalgia, frank arthritis, avascular necrosis)
 		- **Dermatologic** (eg, malar rash, photosensitivity, discoid lupus)

pages/Sings & Symptoms.md

@@ -0,0 +1,36 @@
+- LATER [[Fever]]
+  :LOGBOOK:
+  CLOCK: [2024-10-08 Tue 23:59:33]--[2024-10-08 Tue 23:59:34] =>  00:00:01
+  CLOCK: [2024-10-08 Tue 23:59:36]--[2024-10-08 Tue 23:59:37] =>  00:00:01
+  CLOCK: [2024-10-08 Tue 23:59:38]--[2024-10-08 Tue 23:59:52] =>  00:00:14
+  :END:
+- NOW [[Fatigue]]
+  :LOGBOOK:
+  CLOCK: [2024-10-09 Wed 00:00:01]
+  :END:
+- LATER [[Weight Loss]]
+- LATER [[Night Sweats]]
+- LATER [[Nausea]]
+- LATER [[Vomiting]]
+- LATER [[Diarrhoea]]
+- LATER [[Headache]]
+- LATER [[Paresthesia]]
+- LATER [[Arthralgia]]
+- LATER [[Polyuria]]
+- LATER [[Polydipsia]]
+- LATER [[Rash]]
+- LATER [[Pruritis]]
+- LATER [[Pallor]]
+- LATER [[Bruising]]
+- LATER [[Murphy's Sign]]
+- LATER [[Kernig's Sign]]
+- LATER [[Brudzinki's Sign]]
+- LATER [[Trousseau's Sign]]
+- LATER [[Chvostek's Sign]]
+- LATER [[Rovsing's Sign]]
+- LATER [[Grey Tuerner's Sign]]
+- LATER [[Cullen's Sign]]
+- LATER [[Homan's Sign]]
+- LATER [[Babinski's Sign]]
+- LATER [[Battle's Sign]]
+- LATER [[Romberg's Sign]]

pages/Typhoid Fever.md

@@ -34,7 +34,7 @@ alias:: Enteric Fever
 	- ### Signs and Symptoms
 		- #### Symptoms
 			- Classical Symptoms
-				- [[Fever]]
+				- LATER [[Fever]]
 				- [[Malaise]]
 				- [[Diffuse Abdominal Pain]]
 				- [[Constipation]]

pages/Urdu Poetry.md

@@ -12,5 +12,4 @@
 	- **Main kismat ka maara kyun hoon**
 	  **Tujhe itna chahta kyun hoon**
 	  **Yeh sawaal har pal tumhare labon se jawab chahta hai**
-	  **dil hi dil me jo khat likhe maine wo aab hay kahan gaye **
-	-
+	  **dil hi dil me jo khat likhe maine wo aab hay kahan gaye **

pages/Varicella.md

@@ -0,0 +1,75 @@
+alias:: Chicken Pox
+ICD-11_Code::
+
+- ## Etiology
+  background-color:: blue
+	- ### Causative Agent
+		- Causative Agent : Varicella-Zoster Virus
+		- Mode of Transmission
+			- Respiratory Droplet
+			- Direct Contact
+			- Transplacental
+	- ### Risk Factors
+- ## Epidemiology
+  background-color:: blue
+	- ### Incidence
+		- almost all susceptible children before adolescence
+	- ### Prevalence
+		- ### Demographics
+			- pre-adolescent children
+	- Infection confers lifelong immunity, exception: there have been reinfections in healthy children
+	- ### Geographic Distribution
+- ## Pathophysiology
+  background-color:: blue
+	- ### Mechanism of Disease
+	- ### Affected Systems/Organs
+- ## Clinical Features
+  background-color:: blue
+	- ### Signs and Symptoms
+		- #### Symptoms
+		- #### Signs
+	- ### Stages or Classification
+	- ### Diagnostic Criteria
+- ## Diagnosis
+  background-color:: blue
+	- ### Clinical Diagnosis
+	- ### Laboratory Tests
+	- ### Imaging Studies
+	- ### Differential Diagnosis
+- ## Management and Treatment
+  background-color:: blue
+	- ### Medical Treatment
+	- ### Surgical Options
+	- ### Lifestyle and Dietary Recommendations
+- ## Prognosis
+  background-color:: blue
+	- ### Expected Course
+		- #### With Treatment
+		- #### Without Treatment
+	- ### Survival Rates
+		- #### With Treatment
+		- #### Without Treatment
+	- ### Quality of Life Considerations
+- ## Complications
+  background-color:: blue
+	- ### Possible Complications
+	- ### Long-term Effects
+- ## Prevention
+  background-color:: blue
+	- ### Health Education
+	- ### Community Approach
+	- ### Screening Programs
+	- ### Lifestyle Modifications
+- ## Patient Education and Support
+  background-color:: blue
+	- ### Educational Resources
+	- ### Support Groups
+	- ### Counseling Options
+- ## Recent Research and Developments
+  background-color:: blue
+	- ### Ongoing Clinical Trials
+	- ### Recent Advances
+- ## Key Literature
+  background-color:: blue
+- ## Guidelines and Protocols
+  background-color:: blue