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add dosage of labetalol
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kamranmuazzam committed Oct 24, 2024
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131 changes: 131 additions & 0 deletions logseq/bak/pages/Eclampsia/2024-10-24T17_27_37.089Z.Desktop.md
Original file line number Diff line number Diff line change
@@ -0,0 +1,131 @@
definition:: [[Pre-Eclampsia]] when complicated with grand mal seizures (generalized tonic-clonic convulsions) and/or coma is called eclampsia #obspc
source:: ((671a2fe1-638a-434d-895f-ddf00e3932c9)) [[Dutta Obs]]
ICD-11_Code::

- ## Etiology
background-color:: blue
- ### Causative Agents
- ### Risk Factors
- ## Epidemiology
background-color:: blue
- ### Incidence
- ### Prevalence
- ### Demographics
- ### Geographic Distribution
- ## Pathophysiology
background-color:: blue
- ### Mechanism of Disease
- ### Affected Systems/Organs
- ## Clinical Features
background-color:: blue
- ### Signs and Symptoms
- #### Symptoms
- #### Signs
- ### Stages or Classification #obspc
collapsed:: true
- # Premonitory Stage
duration:: 30 seconds
- The patient becomes unconscious.
- There is twitching of the muscles of the face, tongue and limbs
- Eyeballs roll or are turned to one side become fixed.
- # Tonic Stage
duration:: 30 seconds
- The whole body goes into a tonic spasm the trunk-opisthotonus, limbs and hands clenched.
- Respiration ceases and the tongue protrudes between the teetch
- Cyanosis appears
- Eyeballs become fixed
- # Clonic Stage
duration:: 1-4 minutes
- All the voluntary muscles undergo alterate contraction and relaxation.
- The twitchings start in the face then involve one side of the extremities and ultimately the whole body is involved in the convulsion.
- Biting of the tongue occurs.
- Breathing is stertorous and blood stained frothy secretions fill the mouth; cyanosis gradually disappears.
- # Stage of Coma
- Following the fit, the patient passes on to the stage of coma.
- It may last for a brief period or in others deep coma persists till another convulsion.
- On occasion, the patient appears to be in a confused state following the fit and fails to remember the heppenings.
- Rarely, the coma occurs without prior convulsion
- ### Diagnostic Criteria
- ## Diagnosis
background-color:: blue
- ### Clinical Diagnosis
- ### Laboratory Tests
- ### Imaging Studies
- ### Differential Diagnosis
collapsed:: true
- Epilepsy
- Encephalitis
- Meningitis
- Puerperal cerebral thrombosis
- Hypertensive encephalopathy
- Cerebral malaria in topics
- PRES
- Intracranial tumors
- ## Management and Treatment
background-color:: blue
collapsed:: true
- ### Emergency Management
- Call for extra help, multiple personel are required to simultaneously manage different aspects
- Put the patient in bed and prevent falling to prevent injury
- Put the patient in left lateral recumbent position
- Tongue blade/mouth gag is placed between the teeth
- prevent aspiration
- vomitus and oral secretions removed by frequent suctioning
- Oxygenation is maintained through a face mask(8-10 L/minute) , Intubate if required
- Monitor Saturation with Pulse Oximetry : Arterial Blood Gas analysis is needed when $\ce{O2}$ saturation falls below 92%
- Fluid correction if required, $\ce{NaHCO3}$ if pH<7.1
- Perform cannulation at both hands to maintain two channels
- $\ce{MgSO4}$ in one channel
- Loading Dose : 4-6 g IV slow over 15-20 minute
- Maintenance Dose : 1-2 g/h IV infusion
- [[Labetalol]] in another channel
- Urinary Catheterization
- Diuretics if pulmonary edema
- Fluid Balance, if urine output <30 ml/hour
- Antibiotics to prevent secondary infection
- Monitor
- Fetal Status : Heart Rate
- Magnesium Toxicity
- Respiratory Rate : >12 breath/min
- Knee Jerk (Deep Tendon Reflex)
- Oligouria (normal : >30 ml/hour)
- Delivery (Obstetric Management of Eclampsia)
- ((671634c1-4afb-4d67-b1d2-e6166497fa8d))
- ### Surgical Options
- ### Lifestyle and Dietary Recommendations
- ## Prognosis
background-color:: blue
- ### Expected Course
- #### With Treatment
- follow up for hypertension & proteinuria by 6 weeks time in postnatal clinic
- if continued then further investiagation and consulation with a physician
- #### Without Treatment
- ### Survival Rates
- #### With Treatment
- #### Without Treatment
- ### Quality of Life Considerations
- ## Complications
background-color:: blue
- ### Possible Complications
- ### Long-term Effects
- ## Prevention
background-color:: blue
- ### Prediction and Preventions
- generally, it's preventable in [[Pre-Eclampsia]] but some cases(20-40%) occur without pre-eclamptic state
- ### Health Education
- ### Community Approach
- ### Screening Programs
- ### Lifestyle Modifications
- ## Patient Education and Support
background-color:: blue
- ### Educational Resources
- ### Support Groups
- ### Counseling Options
- ## Recent Research and Developments
background-color:: blue
- ### Ongoing Clinical Trials
- ### Recent Advances
- ## Key Literature
background-color:: blue
- ## Guidelines and Protocols
background-color:: blue
204 changes: 102 additions & 102 deletions pages/Eclampsia.md
Original file line number Diff line number Diff line change
@@ -1,131 +1,131 @@
definition:: [[Pre-Eclampsia]] when complicated with grand mal seizures (generalized tonic-clonic convulsions) and/or coma is called eclampsia #obspc
source:: ((671a2fe1-638a-434d-895f-ddf00e3932c9)) [[Dutta Obs]]
source:: ((671a2fe1-638a-434d-895f-ddf00e3932c9)) [[Dutta Obs]]
ICD-11_Code::

- ## Etiology
background-color:: blue
- ### Causative Agents
- ### Risk Factors
- ### Causative Agents
- ### Risk Factors
- ## Epidemiology
background-color:: blue
- ### Incidence
- ### Prevalence
- ### Demographics
- ### Geographic Distribution
- ### Incidence
- ### Prevalence
- ### Demographics
- ### Geographic Distribution
- ## Pathophysiology
background-color:: blue
- ### Mechanism of Disease
- ### Affected Systems/Organs
- ### Mechanism of Disease
- ### Affected Systems/Organs
- ## Clinical Features
background-color:: blue
- ### Signs and Symptoms
- #### Symptoms
- #### Signs
- ### Stages or Classification #obspc
collapsed:: true
- # Premonitory Stage
duration:: 30 seconds
- The patient becomes unconscious.
- There is twitching of the muscles of the face, tongue and limbs
- Eyeballs roll or are turned to one side become fixed.
- # Tonic Stage
duration:: 30 seconds
- The whole body goes into a tonic spasm the trunk-opisthotonus, limbs and hands clenched.
- Respiration ceases and the tongue protrudes between the teetch
- Cyanosis appears
- Eyeballs become fixed
- # Clonic Stage
duration:: 1-4 minutes
- All the voluntary muscles undergo alterate contraction and relaxation.
- The twitchings start in the face then involve one side of the extremities and ultimately the whole body is involved in the convulsion.
- Biting of the tongue occurs.
- Breathing is stertorous and blood stained frothy secretions fill the mouth; cyanosis gradually disappears.
- # Stage of Coma
- Following the fit, the patient passes on to the stage of coma.
- It may last for a brief period or in others deep coma persists till another convulsion.
- On occasion, the patient appears to be in a confused state following the fit and fails to remember the heppenings.
- Rarely, the coma occurs without prior convulsion
- ### Diagnostic Criteria
- ### Signs and Symptoms
- #### Symptoms
- #### Signs
- ### Stages or Classification #obspc
collapsed:: true
- # Premonitory Stage
duration:: 30 seconds
- The patient becomes unconscious.
- There is twitching of the muscles of the face, tongue and limbs
- Eyeballs roll or are turned to one side become fixed.
- # Tonic Stage
duration:: 30 seconds
- The whole body goes into a tonic spasm the trunk-opisthotonus, limbs and hands clenched.
- Respiration ceases and the tongue protrudes between the teetch
- Cyanosis appears
- Eyeballs become fixed
- # Clonic Stage
duration:: 1-4 minutes
- All the voluntary muscles undergo alterate contraction and relaxation.
- The twitchings start in the face then involve one side of the extremities and ultimately the whole body is involved in the convulsion.
- Biting of the tongue occurs.
- Breathing is stertorous and blood stained frothy secretions fill the mouth; cyanosis gradually disappears.
- # Stage of Coma
- Following the fit, the patient passes on to the stage of coma.
- It may last for a brief period or in others deep coma persists till another convulsion.
- On occasion, the patient appears to be in a confused state following the fit and fails to remember the heppenings.
- Rarely, the coma occurs without prior convulsion
- ### Diagnostic Criteria
- ## Diagnosis
background-color:: blue
- ### Clinical Diagnosis
- ### Laboratory Tests
- ### Imaging Studies
- ### Differential Diagnosis
collapsed:: true
- Epilepsy
- Encephalitis
- Meningitis
- Puerperal cerebral thrombosis
- Hypertensive encephalopathy
- Cerebral malaria in topics
- PRES
- Intracranial tumors
- ### Clinical Diagnosis
- ### Laboratory Tests
- ### Imaging Studies
- ### Differential Diagnosis
collapsed:: true
- Epilepsy
- Encephalitis
- Meningitis
- Puerperal cerebral thrombosis
- Hypertensive encephalopathy
- Cerebral malaria in topics
- PRES
- Intracranial tumors
- ## Management and Treatment
background-color:: blue
collapsed:: true
- ### Emergency Management
- Call for extra help, multiple personel are required to simultaneously manage different aspects
- Put the patient in bed and prevent falling to prevent injury
- Put the patient in left lateral recumbent position
- Tongue blade/mouth gag is placed between the teeth
- prevent aspiration
- vomitus and oral secretions removed by frequent suctioning
- Oxygenation is maintained through a face mask(8-10 L/minute) , Intubate if required
- Monitor Saturation with Pulse Oximetry : Arterial Blood Gas analysis is needed when $\ce{O2}$ saturation falls below 92%
- Fluid correction if required, $\ce{NaHCO3}$ if pH<7.1
- Perform cannulation at both hands to maintain two channels
- $\ce{MgSO4}$ in one channel
- Loading Dose : 4-6 g IV slow over 15-20 minute
- Maintenance Dose : 1-2 g/h IV infusion
- [[Labetalol]] in another channel
- Urinary Catheterization
- Diuretics if pulmonary edema
- Fluid Balance, if urine output <30 ml/hour
- Antibiotics to prevent secondary infection
- Monitor
- Fetal Status : Heart Rate
- Magnesium Toxicity
- Respiratory Rate : >12 breath/min
- Knee Jerk (Deep Tendon Reflex)
- Oligouria (normal : >30 ml/hour)
- Delivery (Obstetric Management of Eclampsia)
- ((671634c1-4afb-4d67-b1d2-e6166497fa8d))
- ### Surgical Options
- ### Lifestyle and Dietary Recommendations
- ### Emergency Management
- Call for extra help, multiple personel are required to simultaneously manage different aspects
- Put the patient in bed and prevent falling to prevent injury
- Put the patient in left lateral recumbent position
- Tongue blade/mouth gag is placed between the teeth
- prevent aspiration
- vomitus and oral secretions removed by frequent suctioning
- Oxygenation is maintained through a face mask(8-10 L/minute) , Intubate if required
- Monitor Saturation with Pulse Oximetry : Arterial Blood Gas analysis is needed when $\ce{O2}$ saturation falls below 92%
- Fluid correction if required, $\ce{NaHCO3}$ if pH<7.1
- Perform cannulation at both hands to maintain two channels
- $\ce{MgSO4}$ in one channel
- Loading Dose : 4-6 g IV slow over 15-20 minute
- Maintenance Dose : 1-2 g/h IV infusion
- [[Labetalol]] in another channel (add dosage and all)
- Urinary Catheterization
- Diuretics if pulmonary edema
- Fluid Balance, if urine output <30 ml/hour
- Antibiotics to prevent secondary infection
- Monitor
- Fetal Status : Heart Rate
- Magnesium Toxicity
- Respiratory Rate : >12 breath/min
- Knee Jerk (Deep Tendon Reflex)
- Oligouria (normal : >30 ml/hour)
- Delivery (Obstetric Management of Eclampsia)
- ((671634c1-4afb-4d67-b1d2-e6166497fa8d))
- ### Surgical Options
- ### Lifestyle and Dietary Recommendations
- ## Prognosis
background-color:: blue
- ### Expected Course
- #### With Treatment
- follow up for hypertension & proteinuria by 6 weeks time in postnatal clinic
- if continued then further investiagation and consulation with a physician
- #### Without Treatment
- ### Survival Rates
- #### With Treatment
- #### Without Treatment
- ### Quality of Life Considerations
- ### Expected Course
- #### With Treatment
- follow up for hypertension & proteinuria by 6 weeks time in postnatal clinic
- if continued then further investiagation and consulation with a physician
- #### Without Treatment
- ### Survival Rates
- #### With Treatment
- #### Without Treatment
- ### Quality of Life Considerations
- ## Complications
background-color:: blue
- ### Possible Complications
- ### Long-term Effects
- ### Possible Complications
- ### Long-term Effects
- ## Prevention
background-color:: blue
- ### Prediction and Preventions
- generally, it's preventable in [[Pre-Eclampsia]] but some cases(20-40%) occur without pre-eclamptic state
- ### Health Education
- ### Community Approach
- ### Screening Programs
- ### Lifestyle Modifications
- ### Prediction and Preventions
- generally, it's preventable in [[Pre-Eclampsia]] but some cases(20-40%) occur without pre-eclamptic state
- ### Health Education
- ### Community Approach
- ### Screening Programs
- ### Lifestyle Modifications
- ## Patient Education and Support
background-color:: blue
- ### Educational Resources
- ### Support Groups
- ### Counseling Options
- ### Educational Resources
- ### Support Groups
- ### Counseling Options
- ## Recent Research and Developments
background-color:: blue
- ### Ongoing Clinical Trials
- ### Recent Advances
- ### Ongoing Clinical Trials
- ### Recent Advances
- ## Key Literature
background-color:: blue
- ## Guidelines and Protocols
background-color:: blue
background-color:: blue

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