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Minimap2-2.6 (r623)

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@lh3 lh3 released this 12 Dec 16:15
· 559 commits to master since this release

This release adds several features and fixes two minor bugs:

  • Optionally build an index without sequences. This helps to reduce the
    peak memory for read overlapping and is automatically applied when
    base-level alignment is not requested.

  • Approximately estimate per-base sequence divergence (i.e. 1-identity)
    without performing base-level alignment, using a MashMap-like method. The
    estimate is written to a new dv:f tag.

  • Reduced the number of tiny terminal exons in RNA-seq alignment. The current
    setting is conservative. Increase --end-seed-pen to drop more such exons.

  • Reduced the peak memory when aligning long query sequences.

  • Fixed a bug that is caused by HPC minimizers longer than 256bp. This should
    have no effect in practice, but it is recommended to rebuild HPC indices if
    possible.

  • Fixed a bug when identifying identical hits (#71). This should only affect
    artifactual reference consisting of near identical sequences.

For genomic sequences, minimap2 should give nearly identical alignments to
v2.5, except the new dv:f tag.

(2.6: 12 December 2017, r623)