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pittacus/perturbation-analyzer
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Authors: pittacus@gmail.com (Fei Li) This project is for PerturbationAnalyzer. INTRODUCTION PerturbationAnalyzer is an open-source plugin for Cytoscape to quantitatively analyze the dynamic characteristics of protein-protein interaction network. This tool automatically evaluates the propagation effects of single perturbation or combinatorial perturba-tions of protein concentrations by comparing two different equilib-rium states which governed by the law of mass action (LMA). With Cytoscape visualization environment, the results are represented visually in an intuitive and customizable way to help identify the key proteins which is mostly perturbed or has largest propagation scope. The results can be saved or exported into standard format for further analysis. DEPENDENCY Cytoscape program directory should be placed into the root directory of project. The Ant script build.xml containds all the build details.
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