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Protein Synthesis and Muscle Building

joshdanko edited this page Jan 9, 2018 · 6 revisions

Muscle Protein Breakdown (MPD)

The breakdown of cell proteins to be used for energy or other processes. When you are in a state of fasting MPD is at it's greatest.

  • Insulin reduces MPD
  • Protein reduces MPD by increasing Insulin
  • Small Insulin increase greatly reduces MPD
  • Training boosts MPD

Muscle Protein Synthesis (MPS)

Building of new muscle proteins. Think of a muscle as a wall. Each brick is a protein. Muscle protein synthesis is the addition of new bricks to the wall (from Muscle Protein Synthesis). Training can

  • Slowed down by MPD
  • Training boosts MPS
  • Distributing protein throughout the day increases MPS (not 1 giant meal)
  • Consuming protein 30-60min before training slows MPD

Important Notes

  • If (MPS - MPD) > 0 then you will build muscle
  • Training increases both MPD and MPS
  • Small Increase in Insulin drastically decreases MPD
  • Protein Increase results in:
    • Increased Insulin resulting in decreased MPD
    • Increased MPS
  • Distributing protein throughout day provides most optimal MPS
  • Resting longer between sets shown to improve MPS

Action Plan

Action Reason
Train many muscle groups at least 2x a week Full body training provides higher MPS than lower-body workout alone.
2min minimum rest between sets Longer rests between sets increases overall MPS.
20-40g protein per meal 20g is optimal amount. Above 20g still positively affects MPS, but the benefit starts to fall of quickly.
Protein for breakfast Distributing protein throughout the day improves MPS.
Protein after workout Distributing protein throughout the day improves MPS.
(Possibly highest synergy with protein intake is post workout, not proven though)
Protein before bed Distributing protein throughout the day improves MPS.

Links for Referenced Info above