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Operational Example 1 (NGS Class II)
mpresteg edited this page Sep 26, 2014
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<?xml version="1.0" encoding="UTF-8"?>
<!--
Histoimmunogenetics Markup Language (HML)
Copyright (c) 2014 National Marrow Donor Program (NMDP)
This specification is free software; you can redistribute it and/or modify it
under the terms of the GNU Lesser General Public License as published
by the Free Software Foundation; either version 3 of the License, or (at
your option) any later version.
This specification is distributed in the hope that it will be useful, but WITHOUT
ANY WARRANTY; with out even the implied warranty of MERCHANTABILITY or
FITNESS FOR A PARTICULAR PURPOSE. See the GNU Lesser General Public
License for more details.
You should have received a copy of the GNU Lesser General Public License
along with this specification; if not, write to the Free Software Foundation,
Inc., 59 Temple Place, Suite 330, Boston, MA 02111-1307 USA.
> http://www.gnu.org/licenses/lgpl.html
-->
<!-- NOTE: This is a brief example of a DRAFT version of HML in action. It is not intended to be an accurate genotyping result. -->
<hml xmlns="http://schemas.nmdp.org/spec/hml/0.9.5"
xmlns:hml="http://schemas.nmdp.org/spec/hml/0.9.5"
xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance"
xsi:schemaLocation="http://schemas.nmdp.org/spec/hml/0.9.5 http://schemas.nmdp.org/spec/hml/0.9.5/hml-0.9.5.xsd"
reporting-center="789"
project-name="LAB"
version="0.9.5">
<sample id="120000089" center-code="123">
<typing gene-family="HLA"><!-- nomenclature="IMGT/HLA Database 3.14.0" -->
<sbt-ngs locus="HLA-DRB1" test-id="GTR000000000.0" test-id-source="NCBI-GTR">
<consensus-sequence>
<targeted-region
assembly="GRCh38"
contig="6"
start="32584377"
end="32584109"
strand="-1"
id="ENSE00001731226"
description="HLA-DRB1 exon 2"/>
<sequence alphabet="DNA">
TTTCTTGGAGCAGGTTAAACATGAGTGTCATTTCTTCAACGGGACGGAGCGGGTGCGGTTCCTGGACA
GATACTTCTATCACCAAGAGGAGTACGTGCGCTTCGACAGCGACGTGGGGGAGTACCGGGCGGTGACG
GAGCTGGGGCGGCCTAGCGCCGAGTACTGGAACAGCCAGAAGGACCTCCTGGAGCAGAGGCGGGCCGA
GGTGGACACCTACTGCAGACACAACTACGGGGTTGTGGAGAGCTTCACA
</sequence>
<sequence alphabet="DNA">
TTTCTTGGAGCAGGTTAAACATGAGTGTCATTTCTTCAACGGGACGGAGCGGGTGCGGTTCCTGGACA
GATACTTCTATCACCAAGAGGAGTACGTGCGCTTCGACAGCGACGTGGGGGAGTACCGGGCGGTGACG
GAGCTGGGGCGGCCTGATGCCGAGTACTGGAACAGCCAGAAGGACCTCCTGGAGCAGAGGCGGGCCGA
GGTGGACACCTACTGCAGACACAACTACGGGGTTGGTGAGAGCTTCACA
</sequence>
</consensus-sequence>
</sbt-ngs>
<interpretation date="2014-01-01" allele-db="IMGT/HLA" allele-version="3.14.0">
<!--
EITHER a single glstring element with a URI -OR- a single glstring
element containing inline data are expected here.
-->
<!-- glstring using inline data: -->
<glstring>
HLA-DRB1*04:11:01+HLA-DRB1*04:07:01/HLA-DRB1*04:92
</glstring>
<!-- glstring using a URI reference: -->
<glstring uri="http://gl.immunogenomics.org/imgt-hla/3.14.0/genotype-list/e" />
</interpretation>
</typing>
</sample>
</hml>
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