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ckennedy-nmdp edited this page Sep 5, 2014 · 2 revisions

With high-throughput technologies, such as NGS, there is a burden of measurability; for example, unlike (non-clonal) Sanger sequencing, where phase and other ambiguities are accepted in routine practice, the quantitative nature of NGS has raised the amount of accessible information per unit cost and consequently raised the burden of proof that the resulting information is accurate. Moving from low- to high-throughput technologies has shifted efforts from data acquisition toward data verification and quality assessment.

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